PDB: 66724 件ウェブページステータス検索Chemie searchBIRD

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8YEJ	Cryo-EM structure of the channelrhodopsin GtCCR2 focused on the monomer 分子名称: GtCCR2, RETINAL 著者 Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. 登録日 2024-02-22 公開日 2024-09-04 最終更新日 2024-09-18 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4. Mol.Cell, 2024
4PC8	Structure-based protein engineering efforts on the scaffold of a monomeric triosephosphate isomerase yielding a sugar isomerase 分子名称: GLYCOLIC ACID, Ma21-TIM 著者 Krause, M, Neubauer, P, Wierenga, R.K. 登録日 2014-04-14 公開日 2015-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for L-arabinose isomerase activity. Acta Crystallogr.,Sect.F, 72, 2016
4P0Y	Structure of the double stranded DNA binding type IV secretion protein TraN from Enterococcus 分子名称: AM32 著者 Goessweiner-mohr, N, Fercher, C, Keller, W. 登録日 2014-02-23 公開日 2014-07-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of the double-stranded DNA-binding type IV secretion protein TraN from Enterococcus. Acta Crystallogr.,Sect.D, 70, 2014
4P1D	Structure of the complex of a bimolecular human telomeric DNA with Coptisine 分子名称: 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, POTASSIUM ION, telomeric DNA 著者 Ferraroni, M, Bazzicalupi, C, Gratteri, P. 登録日 2014-02-26 公開日 2015-03-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of the complex of a bimolecular human telomeric DNA with Coptisine to be published
8ZLD	Crystal structure of PfHO from Plasmodium falciparum at 2.78 A 分子名称: Heme oxygenase, SULFATE ION 著者 Caaveiro, J.M.M, Senoo, A. 登録日 2024-05-18 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis Elife, 2024
4PHP	Structure of human DNA polymerase beta complexed with T in the template base paired with incoming non-hydrolyzable GTP and MANGANESE 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2014-05-06 公開日 2015-05-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The spontaneous base substitution mechanisms of human DNA polymerase beta To Be Published
4P5A	Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMP 分子名称: 5-BROMO-URIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase ThyX 著者 Li, Y, Chen, W, Li, J, Xia, Z, Deng, Z, Zhou, J. 登録日 2014-03-15 公開日 2015-12-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi with 5-Br UMP To Be Published
4PL5	Crystal structure of murine IRE1 in complex with OICR573 inhibitor 分子名称: 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, 3-methoxy-5-methyl-4'-(morpholin-4-yl)biphenyl-4-ol, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Sanches, M, Duffy, N, Talukdar, M, Thevakumaran, N, Chiovitti, D, Al-awar, R, Patterson, J.B, Sicheri, F. 登録日 2014-05-16 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors. Nat Commun, 5, 2014
8ZES	Crystal structure of the Wuhan SARS-CoV-2 RBD (333-541) complexed with P2C5 nanobody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody P2C5, ... 著者 Sluchanko, N.N, Varfolomeeva, L.A, Shcheblyakov, D.V, Logunov, D.Y, Gintsburg, A.L, Popov, V.O, Boyko, K.M. 登録日 2024-05-06 公開日 2024-09-04 最終更新日 2024-09-18 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Structural Basis for Evasion of New SARS-CoV-2 Variants from the Potent Virus-Neutralizing Nanobody Targeting the S-Protein Receptor-Binding Domain. Biochemistry Mosc., 89, 2024
4P7M	Crystal structure of Plasmodium falciparum MIF in complex with 3-[(2-methyl-6-phenylpyridin-4-yl)oxy]phenol 分子名称: 3-[(2-methyl-6-phenylpyridin-4-yl)oxy]phenol, Macrophage migration inhibitory factor-like protein 著者 Pantouris, G, Lolis, E. 登録日 2014-03-27 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Crystallographic and Receptor Binding Characterization of Plasmodium falciparum Macrophage Migration Inhibitory Factor Complexed to Two Potent Inhibitors. J.Med.Chem., 57, 2014
4P7Y	L-methionine gamma-lyase from Citrobacter freundii with Y58F substitution 分子名称: DI(HYDROXYETHYL)ETHER, METHIONINE GAMMA-LYASE, PENTAETHYLENE GLYCOL 著者 Revtovich, S.V, Nikulin, A.D, Anufrieva, N.V, Morozova, E.A, Demidkina, T.V. 登録日 2014-03-28 公開日 2014-11-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with Y58F substitution To Be Published
4PLS	Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure. 分子名称: ACETATE ION, Arm00010, CALCIUM ION 著者 Reichen, C, Madhurantakam, C, Plueckthun, A, Mittl, P.R. 登録日 2014-05-19 公開日 2014-12-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure. Protein Sci., 23, 2014
4P8N	Crystal structure of M. tuberculosis DprE1 in complex with the non-covalent inhibitor QN118 分子名称: 3-[(3-fluoro-4-methoxybenzyl)amino]-6-(trifluoromethyl)quinoxaline-2-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ... 著者 Neres, J, Pojer, F, Cole, S.T. 登録日 2014-03-31 公開日 2014-12-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. Acs Chem.Biol., 10, 2015
4P93	Structure of Dienelactone Hydrolase at 1.85 A resolution crystallised in the C2 space group 分子名称: Carboxymethylenebutenolidase 著者 Porter, J.L, Carr, P.D, Collyer, C.A, Ollis, D.L. 登録日 2014-04-02 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystallization of dienelactone hydrolase in two space groups: structural changes caused by crystal packing. Acta Crystallogr.,Sect.F, 70, 2014
8Z8V	Crystal structure of human serum albumin in complex with ALB8(VHH) domain of ozoralizumab 分子名称: ALB8:VHH, Serum albumin 著者 Mima, M, Mishima-Tsumagari, C. 登録日 2024-04-22 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural design of the anti-TNF alpha therapeutic NANOBODY® compound, ozoralizumab, to support its potent and sustained clinical efficacy. Biochem.Biophys.Res.Commun., 734, 2024
4PMO	Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c, monoclinic crystal form I 分子名称: FORMIC ACID, GLYCEROL, SODIUM ION, ... 著者 Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. 登録日 2014-05-22 公開日 2014-10-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c. J.Struct.Biol., 188, 2014
4P9C	Crystal structure of dCMP deaminase from the cyanophage S-TIM5 in complex with dCMP and dUMP 分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Deoxycytidylate deaminase, ... 著者 Marx, A, Alian, A. 登録日 2014-04-03 公開日 2014-11-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The First Crystal Structure of a dTTP-bound Deoxycytidylate Deaminase Validates and Details the Allosteric-Inhibitor Binding Site. J.Biol.Chem., 290, 2015
6N2F	Meso-Diaminopimelate Decarboxylase from Arabidopsis thaliana (Isoform 2) 分子名称: Diaminopimelate decarboxylase 2, chloroplastic, LYSINE, ... 著者 Crowther, J.M, Dobson, R.C.J. 登録日 2018-11-12 公開日 2019-04-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Active site gating provides stereochemical control for meso-diaminopimelate decarboxylase To Be Published
4PAA	Crystal structure of the mature form of rat DMGDH complexed with tetrahydrofolate 分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, Dimethylglycine dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE 著者 Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C. 登録日 2014-04-07 公開日 2014-06-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate. Biochem.Biophys.Res.Commun., 449, 2014
8YEK	Cryo-EM structure of the channelrhodopsin GtCCR2 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GtCCR2, RETINAL 著者 Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. 登録日 2024-02-22 公開日 2024-09-04 最終更新日 2024-09-18 実験手法 ELECTRON MICROSCOPY (2.73 Å) 主引用文献 The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4. Mol.Cell, 2024
2YJW	Tricyclic series of Hsp90 inhibitors 分子名称: 4-(5-METHYL-4-PHENYLISOXAZOL-3-YL)BENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP 90-ALPHA 著者 Dupuy, A, Vallee, F. 登録日 2011-05-24 公開日 2011-10-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-C]Pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone. J.Med.Chem., 54, 2011
8XH2	Orthorhombic crystal structure of green fluorescent protein nowGFP at pH 6.0 分子名称: GLYCEROL, nowGFP 著者 Kim, C.U, Kim, J.K. 登録日 2023-12-16 公開日 2024-09-11 最終更新日 2024-09-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Comparison of two crystal polymorphs of NowGFP reveals a new conformational state trapped by crystal packing. Acta Crystallogr D Struct Biol, 80, 2024
8QJ5	Crystal structure of the Levansucrase beta from Pseudomonas syringae pv. actinidiae 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, GLYCEROL, ... 著者 Ferraroni, M, Peritore, L. 登録日 2023-09-12 公開日 2024-09-25 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Crystal structure of the Levansucrase beta from Pseudomonas syringae pv. actinidiae To Be Published
8ZER	Crystal structure of the complex of Wuhan SARS-CoV-2 RBD (319-541) with P2C5 nanobody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody P2C5, Spike protein S1, ... 著者 Sluchanko, N.N, Varfolomeeva, L.A, Shcheblyakov, D.V, Logunov, D.Y, Gintsburg, A.L, Popov, V.O, Boyko, K.M. 登録日 2024-05-06 公開日 2024-09-04 最終更新日 2024-09-18 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Basis for Evasion of New SARS-CoV-2 Variants from the Potent Virus-Neutralizing Nanobody Targeting the S-Protein Receptor-Binding Domain. Biochemistry Mosc., 89, 2024
4P3J	Apo inward-facing state of the glutamate transporter homologue GltPh in alkali-free conditions 分子名称: GltPh, MERCURY (II) ION 著者 Verdon, G, Boudker, O. 登録日 2014-03-08 公開日 2014-06-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Coupled ion binding and structural transitions along the transport cycle of glutamate transporters. Elife, 3, 2014

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