2O2E
 
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3IW0
 | | Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125, C2221 crystal form | | 分子名称: | Cytochrome P450 CYP125, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | McLean, K.J, Levy, C, Munro, A.W, Leys, D. | | 登録日 | 2009-09-02 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.
J.Biol.Chem., 284, 2009
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3IW1
 | | Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with androstenedione | | 分子名称: | 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | McLean, K.J, Levy, C, Munro, A.W, Leys, D. | | 登録日 | 2009-09-02 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.
J.Biol.Chem., 284, 2009
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1ZYU
 | | Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimate and amppcp at 2.85 angstrom resolution | | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Shikimate kinase | | 著者 | Gan, J.H, Gu, Y.J, Li, Y, Yan, H.G, Ji, X. | | 登録日 | 2005-06-11 | | 公開日 | 2006-07-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue
Biochemistry, 45, 2006
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2Q3C
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3C8Z
 | | The 1.6 A Crystal Structure of MshC: The Rate Limiting Enzyme in the Mycothiol Biosynthetic Pathway | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, Cysteinyl-tRNA synthetase, ... | | 著者 | Tremblay, L.W, Fan, F, Vetting, M.W, Blanchard, J.S. | | 登録日 | 2008-02-14 | | 公開日 | 2008-12-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The 1.6 A crystal structure of Mycobacterium smegmatis MshC: the penultimate enzyme in the mycothiol biosynthetic pathway.
Biochemistry, 47, 2008
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2Q3B
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2G1J
 | | Crystal structure of Mycobacterium tuberculosis Shikimate Kinase at 2.0 angstrom resolution | | 分子名称: | SULFATE ION, Shikimate kinase | | 著者 | Gan, J, Gu, Y, Li, Y, Yan, H, Ji, X. | | 登録日 | 2006-02-14 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue.
Biochemistry, 45, 2006
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2AQ8
 | | Crystal structure of wild-type of Enoyl-ACP(CoA) reductase from Mycobacterium tuberculosis in complex with NADH. | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-Acyl-carrier-protein reductase, LYSINE | | 著者 | Oliveira, J.S, Pereira, J.H, Rodrigues, N.C, Canduri, F, Basso, L.A, de Azevedo Jr, W.F, Santos, D.S. | | 登録日 | 2005-08-17 | | 公開日 | 2006-05-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis.
J.Mol.Biol., 359, 2006
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2AQK
 | | Crystal structure of Isoniazid-resistant S94A Enoyl-ACP(CoA) reductase mutant enzyme from Mycobacterium tuberculosis in complex with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH] | | 著者 | Oliveira, J.S, Pereira, J.H, Rodrigues, N.C, Canduri, F, de Souza, O.N, Basso, L.A, de Azevedo Jr, W.F, Santos, D.S. | | 登録日 | 2005-08-18 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis.
J.Mol.Biol., 359, 2006
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1ME5
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4JN6
 | | Crystal Structure of the Aldolase-Dehydrogenase Complex from Mycobacterium tuberculosis HRv37 | | 分子名称: | 4-hydroxy-2-oxovalerate aldolase, Acetaldehyde dehydrogenase, MANGANESE (II) ION, ... | | 著者 | Carere, J, McKenna, S.E, Kimber, M.S, Seah, S.Y.K. | | 登録日 | 2013-03-14 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Characterization of an Aldolase-Dehydrogenase Complex from the Cholesterol Degradation Pathway of Mycobacterium tuberculosis.
Biochemistry, 52, 2013
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1XDU
 | | Crystal structure of Aclacinomycin-10-hydroxylase (RdmB) in complex with Sinefungin (SFG) | | 分子名称: | ACETATE ION, Protein RdmB, SINEFUNGIN | | 著者 | Jansson, A, Koskiniemi, H, Erola, A, Wang, J, Mantsala, P, Schneider, G, Niemi, J. | | 登録日 | 2004-09-08 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Aclacinomycin 10-Hydroxylase Is a Novel Substrate-assisted Hydroxylase Requiring S-Adenosyl-L-methionine as Cofactor
J.Biol.Chem., 280, 2005
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2AQI
 | | Crystal structure of Isoniazid-resistant I47T Enoyl-ACP(CoA) reductase mutant enzyme from Mycobacterium tuberculosis in complex with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH] | | 著者 | Oliveira, J.S, Pereira, J.H, Rodrigues, N.C, Canduri, F, de Souza, O.N, Basso, L.A, de Azevedo Jr, W.F, Santos, D.S. | | 登録日 | 2005-08-18 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis.
J.Mol.Biol., 359, 2006
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2QXX
 | | Bifunctional dCTP deaminase: dUTPase from Mycobacterium tuberculosis in complex with dTTP | | 分子名称: | Deoxycytidine triphosphate deaminase, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | | 著者 | Christophersen, S, Harris, P, Willemoes, M. | | 登録日 | 2007-08-13 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis.
J.Mol.Biol., 376, 2008
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1NFQ
 | | Rv2002 gene product from Mycobacterium tuberculosis | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Androsterone, Putative oxidoreductase Rv2002 | | 著者 | Yang, J.K, Park, M.S, Waldo, G.S, Suh, S.W, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2002-12-15 | | 公開日 | 2002-12-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis
Proc.Natl.Acad.Sci.USA, 100, 2003
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1NH7
 | | ATP PHOSPHORIBOSYLTRANSFERASE (ATP-PRTASE) FROM MYCOBACTERIUM TUBERCULOSIS | | 分子名称: | ATP Phosphoribosyltransferase, MAGNESIUM ION, SULFATE ION | | 著者 | Cho, Y, Sharma, V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2002-12-18 | | 公開日 | 2003-02-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of ATP Phosphoribosyltransferase from Mycobacterium Tuberculosis
J.Biol.Chem., 278, 2003
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1N8I
 | | Biochemical and Structural Studies of Malate Synthase from Mycobacterium tuberculosis | | 分子名称: | GLYOXYLIC ACID, MAGNESIUM ION, Probable malate synthase G | | 著者 | Smith, C.V, Huang, C.C, Miczak, A, Russell, D.G, Sacchettini, J.C, Honer zu Bentrup, K, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2002-11-20 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis
J.Biol.Chem., 278, 2003
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1N8W
 | | Biochemical and Structural Studies of Malate Synthase from Mycobacterium tuberculosis | | 分子名称: | COENZYME A, D-MALATE, GLYOXYLIC ACID, ... | | 著者 | Smith, C.V, Huang, C.C, Miczak, A, Russell, D.G, Sacchettini, J.C, Honer zu Bentrup, K, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2002-11-21 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis
J.Biol.Chem., 278, 2003
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1SR9
 | | Crystal Structure of LeuA from Mycobacterium tuberculosis | | 分子名称: | 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, CHLORIDE ION, ... | | 著者 | Koon, N, Squire, C.J, Baker, E.N. | | 登録日 | 2004-03-22 | | 公開日 | 2004-05-18 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis
Proc.Natl.Acad.Sci.USA, 101, 2004
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5EDT
 | | Crystal structure of Mycobacterium tuberculosis CYP121 in complex with LIG9 | | 分子名称: | 2-azanyl-5-chloranyl-benzamide, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Kavanagh, M.E, Coyne, A.G, McLean, K.J, James, G.G, Levy, C, Marino, L.B, Carvalho, L.P.D, Chan, D.S.H, Hudson, S.A, Surade, S, Munro, A.W, Abell, C. | | 登録日 | 2015-10-22 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors.
J.Med.Chem., 59, 2016
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3ERE
 | | Crystal structure of the arginine repressor protein from Mycobacterium tuberculosis in complex with the DNA operator | | 分子名称: | 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DAP*DAP*DCP*DGP*DAP*DTP*DGP*DCP*DAP*DA)-3', 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DCP*DGP*DTP*DTP*DAP*DTP*DGP*DCP*DAP*DA)-3', Arginine repressor, ... | | 著者 | Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2008-10-01 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis.
J.Mol.Biol., 384, 2008
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1YL6
 | | crystal structure of Mycobacterium tuberculosis dihydrodipicolinate reductase (Rv2773c) (crystal form B) | | 分子名称: | Dihydrodipicolinate reductase, MAGNESIUM ION | | 著者 | Janowski, R, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2005-01-19 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The structure of dihydrodipicolinate reductase (DapB) from Mycobacterium tuberculosis in three crystal forms.
Acta Crystallogr.,Sect.D, 66, 2010
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1YL5
 | | Crystal structure of Mycobacterium tuberculosis dihydrodipicolinate reductase (RV2773C) (crystal form A) | | 分子名称: | Dihydrodipicolinate reductase, MAGNESIUM ION | | 著者 | Janowski, R, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2005-01-19 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The structure of dihydrodipicolinate reductase (DapB) from Mycobacterium tuberculosis in three crystal forms.
Acta Crystallogr.,Sect.D, 66, 2010
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5GVX
 | | Structural insight into dephosphorylation by Trehalose 6-phosphate Phosphatase (OtsB2) from Mycobacterium Tuberculosis | | 分子名称: | MAGNESIUM ION, Trehalose-phosphate phosphatase | | 著者 | Shan, S, Min, H, Liu, T, Jiang, D, Rao, Z. | | 登録日 | 2016-09-07 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | | 主引用文献 | Structural insight into dephosphorylation by trehalose 6-phosphate phosphatase (OtsB2) from Mycobacterium tuberculosis.
FASEB J., 30, 2016
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