PDB: 2824 件ウェブページステータス検索Chemie searchBIRD

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1E2J	The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography 分子名称: SULFATE ION, THYMIDINE, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2000-11-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41, 2000
1E2H	The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography 分子名称: SULFATE ION, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2000-11-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41, 2000
4LV1	AmpC beta-lactamase in complex with [1-(3-chlorophenyl)-1H-pyrazol-4-yl] boronic acid 分子名称: Beta-lactamase, PHOSPHATE ION, [1-(3-chlorophenyl)-1H-pyrazol-4-yl]boronic acid 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
8AMZ	Spinach 19S proteasome 分子名称: 26S proteasome non-ATPase regulatory subunit 1 homolog, 26S proteasome non-ATPase regulatory subunit 2 homolog, 26S proteasome regulatory subunit 7, ... 著者 Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D. 登録日 2022-08-04 公開日 2022-08-24 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of the plant 26S proteasome Plant Communications, 3, 2022
4LV3	AmpC beta-lactamase in complex with (3,5-di-tert-butylphenyl) boronic acid 分子名称: (3,5-di-tert-butylphenyl)boronic acid, Beta-lactamase, PHOSPHATE ION 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
7PVO	Adenylosuccinate Synthetase from H. pylori in complex with IMP 分子名称: Adenylosuccinate synthetase, INOSINIC ACID, SULFATE ION 著者 Narczyk, M, Bzowska, A, Maksymiuk, W. 登録日 2021-10-05 公開日 2022-11-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site. Int.J.Biol.Macromol., 226, 2023
8AX5	Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029881 分子名称: (1~{R},10~{R},20~{E})-12-methyl-10-[(7-methyl-2~{H}-indazol-5-yl)methyl]-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3,5,7(30),20,22,24,28-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ... 著者 Southall, S.M, Watson, S.P. 登録日 2022-08-30 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode. Acs Med.Chem.Lett., 13, 2022
8AX6	Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029882 分子名称: (1~{S},10~{R},20~{E})-12-methyl-10-[(7-methyl-2~{H}-indazol-5-yl)methyl]-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3(30),4,6,20,22,24,28-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ... 著者 Southall, S.M, Watson, S.P. 登録日 2022-08-30 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode. Acs Med.Chem.Lett., 13, 2022
8AX7	Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0031448 分子名称: (1~{S},10~{R},20~{E})-10-[(1,7-dimethylindazol-5-yl)methyl]-12-methyl-15,18-dioxa-9,12,24,26-tetrazapentacyclo[20.5.2.1^{1,4}.1^{3,7}.0^{25,28}]hentriaconta-3(30),4,6,20,22,24,28-heptaene-8,11,27-trione, ACETATE ION, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, ... 著者 Southall, S.M, Watson, S.P. 登録日 2022-08-30 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode. Acs Med.Chem.Lett., 13, 2022
4M8T	RSK2 T493M C-Terminal Kinase Domain in complex with 3-(3-(1H-pyrazol-4-yl)phenyl)-2-cyanoacrylamide 分子名称: (2E)-2-cyano-3-[3-(1H-pyrazol-4-yl)phenyl]prop-2-enamide, Ribosomal protein S6 kinase alpha-3, SODIUM ION 著者 Miller, R.M, Taunton, J. 登録日 2013-08-13 公開日 2014-10-22 最終更新日 2014-11-26 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
7QVE	Spinach 20S proteasome 分子名称: Proteasome subunit alpha type, Proteasome subunit alpha type-3, Proteasome subunit beta, ... 著者 Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D. 登録日 2022-01-21 公開日 2022-05-25 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of the plant 26S proteasome. Plant Commun., 3, 2022
8ARL	Plasmodium vivax PVP01_0000100 TRAg domain 分子名称: Tryptophan-rich antigen 著者 Kundu, P, Deane, J.E, Rayner, J.C. 登録日 2022-08-17 公開日 2023-07-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The structure of a Plasmodium vivax Tryptophan Rich Antigen domain suggests a lipid binding function for a pan-Plasmodium multi-gene family. Nat Commun, 14, 2023
8ARD	Myosin VI proximal tail domain, dimeric 分子名称: Unconventional myosin-VI 著者 Kikuti, C.M, Sirkia, H, Houdusse, A. 登録日 2022-08-16 公開日 2023-08-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.219 Å) 主引用文献 How myosin VI traps its off-state, is activated and dimerizes. Nat Commun, 14, 2023
4LV0	AmpC beta-lactamase in complex with m-aminophenyl boronic acid 分子名称: Beta-lactamase, M-AMINOPHENYLBORONIC ACID, PHOSPHATE ION 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.652 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
4MB8	Evolutionary history and metabolic insights of ancient mammalian uricases 分子名称: ACETATE ION, Uricase 著者 Ortlund, E.O, Murphy, M.N. 登録日 2013-08-19 公開日 2014-02-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4009 Å) 主引用文献 Evolutionary history and metabolic insights of ancient mammalian uricases. Proc.Natl.Acad.Sci.USA, 111, 2014
4LV2	AmpC beta-lactamase in complex with [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl] boronic acid 分子名称: Beta-lactamase, PHOSPHATE ION, [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl]boronic acid 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
8BJA	Structure of the human UBR5 Dimer. 分子名称: E3 ubiquitin-protein ligase UBR5, ZINC ION 著者 Hodakova, Z, Grishkovskaya, I, Haselbach, D. 登録日 2022-11-03 公開日 2023-07-12 最終更新日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5. Embo J., 42, 2023
7RDA	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.138 分子名称: Circumsporozoite protein, antibody m43.138 heavy chain, antibody m43.138 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-09 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RD9	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.159 分子名称: Circumsporozoite protein, antibody m43.159 heavy chain, antibody m43.159 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-09 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RD3	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.126 分子名称: Circumsporozoite protein, antibody m42.126 heavy chain, antibody m42.126 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-09 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RAJ	Structure of PfCSP peptide 21 with antibody iGL-CIS43.D3 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN-ALA-ASN, ZINC ION, ... 著者 Tripathi, P, Kwong, P.D. 登録日 2021-07-01 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RCS	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.160 分子名称: Circumsporozoite protein, antibody m43.160 heavy chain, antibody m43.160 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-08 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RD4	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.149 分子名称: Circumsporozoite protein, antibody m43.149 heavy chain, antibody m43.149 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-09 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RQQ	Structure of chimeric antibody F10heavy_L9light with PfCSP peptide NANPNVDP 分子名称: 1,2-ETHANEDIOL, F10 Heavy Chain, L9 Kappa Chain, ... 著者 Hurlburt, N.K, Pancera, M. 登録日 2021-08-06 公開日 2022-03-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. Cell Rep, 38, 2022
7RQP	Structure of PfCSP NPNV binding antibody L9 分子名称: L9 Heavy Chain, L9 Kappa Chain 著者 Hurlburt, N.K, Pancera, M. 登録日 2021-08-06 公開日 2022-03-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. Cell Rep, 38, 2022

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