PDB: 7386 件ウェブページステータス検索Chemie searchBIRD

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7TQL	CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B. 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D. 登録日 2022-01-26 公開日 2022-04-27 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature, 607, 2022
4W29	70S ribosome translocation intermediate containing elongation factor EFG/GDP/fusidic acid, mRNA, and tRNAs trapped in the AP/AP pe/E chimeric hybrid state. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F. 登録日 2014-07-02 公開日 2014-10-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation. Science, 345, 2014
6OKK	Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Wong, W, Scheres, S.H.W. 登録日 2019-04-13 公開日 2019-05-22 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
2ZJR	Refined native structure of the large ribosomal subunit (50S) from Deinococcus radiodurans 分子名称: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. 登録日 2008-03-08 公開日 2008-06-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol.Cell, 30, 2008
6OF1	Crystal structure of the Thermus thermophilus 70S ribosome in complex with dirithromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.80A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Khabibullina, N.F, Tereshchenkov, A.G, Komarova, E.S, Syroegin, E.A, Shiriaev, D.I, Paleskava, A, Kartsev, V.G, Bogdanov, A.A, Konevega, A.L, Dontsova, O.A, Sergiev, P.V, Osterman, I.A, Polikanov, Y.S. 登録日 2019-03-28 公開日 2019-04-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides. Antimicrob.Agents Chemother., 63, 2019
8CRX	Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound 分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Lomakin, I.B, Devarkar, S.C, Bunick, C.G. 登録日 2022-05-12 公開日 2023-03-22 最終更新日 2023-04-19 実験手法 ELECTRON MICROSCOPY (2.78 Å) 主引用文献 Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
7ZJX	Rabbit 80S ribosome programmed with SECIS and SBP2 分子名称: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... 著者 Hilal, T, Simonovic, M, Spahn, C.M.T. 登録日 2022-04-12 公開日 2022-09-07 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
7ZJW	Rabbit 80S ribosome as it decodes the Sec-UGA codon 分子名称: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... 著者 Hilal, T, Simonovic, M, Spahn, C.M.T. 登録日 2022-04-12 公開日 2022-10-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science, 376, 2022
6CAS	Serial Femtosecond X-ray Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with N1MS 分子名称: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 DeMirci, H. 登録日 2018-01-31 公開日 2018-07-25 最終更新日 2018-10-24 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature. Nucleic Acids Res., 46, 2018
6CAR	Serial Femtosecond X-ray Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin 分子名称: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... 著者 DeMirci, H. 登録日 2018-01-31 公開日 2018-07-25 最終更新日 2018-10-24 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature. Nucleic Acids Res., 46, 2018
3A1Y	The structure of archaeal ribosomal stalk P1/P0 complex 分子名称: 50S ribosomal protein P1 (L12P), Acidic ribosomal protein P0 著者 Naganuma, T, Yao, M, Nomura, N, Yu, J, Uchiumi, T, Tanaka, I. 登録日 2009-04-25 公開日 2009-11-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural basis for translation factor recruitment to the eukaryotic/archaeal ribosomes J.Biol.Chem., 285, 2010
1QZC	Coordinates of S12, SH44, LH69 and SRL separately fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S12 著者 Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. 登録日 2003-09-16 公開日 2003-11-04 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
8CVO	Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, head domain only in the local refined map 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ... 著者 Lomakin, I.B, Devarkar, S.C, Bunick, C.G. 登録日 2022-05-18 公開日 2023-03-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
8CWO	Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, body domain only in the local refined map 分子名称: 16S ribosomal RNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Lomakin, I.B, Devarkar, S.C, Bunick, C.G. 登録日 2022-05-19 公開日 2023-03-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
3I56	Co-crystal structure of Triacetyloleandomcyin Bound to the Large Ribosomal Subunit 分子名称: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... 著者 Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B. 登録日 2009-07-03 公開日 2010-03-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui. Antimicrob.Agents Chemother., 53, 2009
1R2X	Coordinates of L11 with 58nts of 23S rRNA fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome 分子名称: 50S ribosomal protein L11, 58nts of 23S rRNA 著者 Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. 登録日 2003-09-30 公開日 2003-11-04 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
1R2W	Coordinates of L11 with 58nts of 23S rRNA fitted into the cryo-EM map of the 70S ribosome 分子名称: 50S ribosomal protein L11, 58nts of 23S rRNA 著者 Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. 登録日 2003-09-30 公開日 2003-11-04 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
4BU2	60S ribosomal protein L27A histidine hydroxylase (MINA53) in complex with Ni(II) and 2-oxoglutarate (2OG) 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, ... 著者 Chowdhury, R, Clifton, I.J, McDonough, M.A, Ng, S.S, Pilka, E, Oppermann, U, Schofield, C.J. 登録日 2013-06-19 公開日 2014-05-14 最終更新日 2019-02-06 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014
7QQ3	Cryo-EM structure of the E.coli 50S ribosomal subunit in complex with the antibiotic Myxovalargin A. 分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Koller, T.O, Beckert, B, Wilson, D.N. 登録日 2022-01-06 公開日 2023-01-18 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (2.1 Å) 主引用文献 The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. J.Am.Chem.Soc., 145, 2023
1KC8	Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit 分子名称: 23S RRNA, 5S RRNA, BLASTICIDIN S, ... 著者 Hansen, J.L, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. 登録日 2001-11-07 公開日 2003-07-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
3J79	Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. 登録日 2014-06-02 公開日 2014-07-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
1GYZ	Bacterial ribosomal protein L20 from Aquifex aeolicus 分子名称: 50S RIBOSOMAL PROTEIN L20 著者 Raibaud, S, Lebars, I, Bontems, F, Dardel, F. 登録日 2002-05-02 公開日 2002-05-10 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Structure of Bacterial Ribosomal Protein L20: Implications for Ribosome Assembly and Translational Control J.Mol.Biol., 323, 2002
6QDW	Cryo-EM structure of the 50S ribosomal subunit at 2.83 Angstroms with modeled GBC SecM peptide 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Schulte, L, Reitz, J, Hodirnau, V.V, Kudlinzki, D, Mao, J, Glaubitz, C, Frangakis, A, Schwalbe, H. 登録日 2019-01-03 公開日 2020-01-15 最終更新日 2020-12-02 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 Cysteine oxidation and disulfide formation in the ribosomal exit tunnel. Nat Commun, 11, 2020
5NP6	70S structure prior to bypassing 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Agirrezabala, X, Samatova, E, Klimova, M, Zamora, M, Gil-Carton, D, Rodnina, M, Valle, M. 登録日 2017-04-13 公開日 2017-06-14 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ribosome rearrangements at the onset of translational bypassing. Sci Adv, 3, 2017
1K73	Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit 分子名称: 23S RRNA, 5S RRNA, ANISOMYCIN, ... 著者 Hansen, J, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. 登録日 2001-10-18 公開日 2003-07-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit J.Mol.Biol., 330, 2003

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