4WNS
| Crystal structure of Transthyretin complexed with pterostilbene | 分子名称: | DIMETHYL SULFOXIDE, Pterostilbene, SULFATE ION, ... | 著者 | Zanotti, G, Cianci, M, Folli, C, Berni, R. | 登録日 | 2014-10-14 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Structural evidence for asymmetric ligand binding to transthyretin. Acta Crystallogr.,Sect.D, 71, 2015
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7Z3J
| Structure of crystallisable rat Phospholipase C gamma 1 in complex with inositol 1,4,5-trisphosphate | 分子名称: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | 著者 | Pinotsis, N, Bunney, T.D, Katan, M. | 登録日 | 2022-03-02 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Characterization of the membrane interactions of phospholipase C gamma reveals key features of the active enzyme. Sci Adv, 8, 2022
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4WNJ
| Crystal structure of Transthyretin-quercetin complex | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DIMETHYL SULFOXIDE, Transthyretin | 著者 | Zanotti, G, Cianci, M, Berni, R, Folli, C. | 登録日 | 2014-10-13 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.398 Å) | 主引用文献 | Structural evidence for asymmetric ligand binding to transthyretin. Acta Crystallogr.,Sect.D, 71, 2015
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4YX7
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4I87
| Crystal structure of TTR variant I84S in complex with CHF5074 at acidic pH | 分子名称: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | 著者 | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | 登録日 | 2012-12-03 | 公開日 | 2013-06-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors. Febs Lett., 587, 2013
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4I85
| Crystal structure of transthyretin in complex with CHF5074 at neutral pH | 分子名称: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | 著者 | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | 登録日 | 2012-12-03 | 公開日 | 2013-06-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors. Febs Lett., 587, 2013
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5IFN
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8SH4
| Crystal structure of the tRNA (m1G37) methyltransferase apoenzyme from Anaplasma phagocytophilum | 分子名称: | GLYCEROL, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Jannotta, C, Edele, D, Levanti, D, Carson, M, Prucha, G, Caesar, J, Picchiello, C, Collins, K, Garland, E, Handley-Pendleton, J, Hernandez, V, Leffler, S, Williams, D, Stojanoff, V, Perez, A, Halloran, J, Bolen, R. | 登録日 | 2023-04-13 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the m1G37 tRNA methyltransferase apoenzyme from Anaplasma phagocytophilum To Be Published
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7ADM
| Structure of the mycoplasma MIB protein | 分子名称: | Putative immunoglobulin-blocking virulence protein | 著者 | Nottelet, P, Bataille, L, Gourgues, G, Anger, R, Lartigue, C, Sirand-Pugnet, P, Marza, E, Fronzes, R, Arfi, Y. | 登録日 | 2020-09-15 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The mycoplasma surface proteins MIB and MIP promote the dissociation of the antibody-antigen interaction. Sci Adv, 7, 2021
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7ADJ
| Structure of the mycoplasma MIB protein | 分子名称: | Putative immunoglobulin-blocking virulence protein | 著者 | Nottelet, P, Bataille, L, Gourgues, G, Anger, R, Lartigue, C, Sirand-Pugnet, P, Marza, E, Fronzes, R, Arfi, Y. | 登録日 | 2020-09-15 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The mycoplasma surface proteins MIB and MIP promote the dissociation of the antibody-antigen interaction. Sci Adv, 7, 2021
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7ADK
| Structure of the mycoplasma MIB and MIP proteins | 分子名称: | Lipoprotein, Putative immunoglobulin-blocking virulence protein | 著者 | Nottelet, P, Bataille, L, Gourgues, G, Anger, R, Lartigue, C, Sirand-Pugnet, P, Marza, E, Fronzes, R, Arfi, Y. | 登録日 | 2020-09-15 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The mycoplasma surface proteins MIB and MIP promote the dissociation of the antibody-antigen interaction. Sci Adv, 7, 2021
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6P7M
| Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (1:2 complex) | 分子名称: | Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ... | 著者 | Knott, G.J, Liu, J.J, Doudna, J.A. | 登録日 | 2019-06-06 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a. Elife, 8, 2019
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5LQY
| Structure of F-ATPase from Pichia angusta, in state2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase OSCP subunit, ... | 著者 | Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E. | 登録日 | 2016-08-17 | 公開日 | 2016-11-16 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5LQX
| Structure of F-ATPase from Pichia angusta, state3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase AAP1 subunit, ... | 著者 | Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E. | 登録日 | 2016-08-17 | 公開日 | 2016-11-16 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6P7N
| Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (2:2 complex) | 分子名称: | Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ... | 著者 | Knott, G.J, Liu, J.J, Doudna, J.A. | 登録日 | 2019-06-06 | 公開日 | 2019-08-21 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a. Elife, 8, 2019
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5LQZ
| Structure of F-ATPase from Pichia angusta, state1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase OSCP subunit, ... | 著者 | Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E. | 登録日 | 2016-08-17 | 公開日 | 2016-11-16 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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7KG4
| Recombinant Beta-2-Glycoprotein I antibody recognition loop mutant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Klenotic, P.A, Yu, E.W. | 登録日 | 2020-10-15 | 公開日 | 2021-10-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Beta-2-Glycoprotein I and its role in APS To be published
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7QE3
| Se-M variant of B-trefoil lectin from Salpingoeca rosetta in complex with GalNAc | 分子名称: | (2S)-hexane-1,2,6-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose, ... | 著者 | Notova, S, Varrot, A. | 登録日 | 2021-12-01 | 公開日 | 2022-09-14 | 最終更新日 | 2022-09-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3. Commun Biol, 5, 2022
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7QE4
| B-trefoil lectin from Salpingoeca rosetta in complex with GalNAc | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, CHLORIDE ION, ... | 著者 | Notova, S, Varrot, A. | 登録日 | 2021-12-01 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3. Commun Biol, 5, 2022
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6I02
| Structure of human D-glucuronyl C5 epimerase in complex with product | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Debarnot, C, Monneau, Y.R, Roig-Zamboni, V, Le Narvor, C, Goulet, A, Fadel, F, Vives, R.R, Bonnaffe, D, Lortat-Jacob, H, Bourne, Y. | 登録日 | 2018-10-24 | 公開日 | 2019-04-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase. Proc.Natl.Acad.Sci.USA, 116, 2019
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6HZZ
| Structure of human D-glucuronyl C5 epimerase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Debarnot, C, Monneau, Y.R, Roig-Zamboni, V, Le Narvor, C, Goulet, A, Fadel, F, Vives, R.R, Bonnaffe, D, Lortat-Jacob, H, Bourne, Y. | 登録日 | 2018-10-24 | 公開日 | 2019-04-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase. Proc.Natl.Acad.Sci.USA, 116, 2019
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5NL6
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7R55
| B-trefoil lectin from Salpingoeca rosetta in complex with Gb3 | 分子名称: | 1,2-ETHANEDIOL, Sarol-1, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Notova, S, Varrot, A. | 登録日 | 2022-02-10 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3. Commun Biol, 5, 2022
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4YX5
| SpaO(SPOA1,2) | 分子名称: | CHLORIDE ION, Surface presentation of antigens protein SpaO | 著者 | Notti, R.Q, Stebbins, C.E. | 登録日 | 2015-03-22 | 公開日 | 2015-06-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9001 Å) | 主引用文献 | A common assembly module in injectisome and flagellar type III secretion sorting platforms. Nat Commun, 6, 2015
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6I01
| Structure of human D-glucuronyl C5 epimerase in complex with substrate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Debarnot, C, Monneau, Y.R, Roig-Zamboni, V, Le Narvor, C, Goulet, A, Fadel, F, Vives, R.R, Bonnaffe, D, Lortat-Jacob, H, Bourne, Y. | 登録日 | 2018-10-24 | 公開日 | 2019-04-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase. Proc.Natl.Acad.Sci.USA, 116, 2019
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