6ZT2
| 17beta-hydroxysteroid dehydrogenase type 14 variant S205 in complex with 3-chloro-2,6-difluorophenol | 分子名称: | 17-beta-hydroxysteroid dehydrogenase 14, 3-chloranyl-2,6-bis(fluoranyl)phenol, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Badran, M.J, Heine, A, Klebe, G. | 登録日 | 2020-07-17 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | 17beta-hydroxysteroid dehydrogenase type 14 variant S205 in complex with 3-chloro-2,6-difluorophenol To Be Published
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7A1I
| Crystal structure of the BILBO2/FPC4 complex | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BILBO1_N domain-containing protein, ... | 著者 | Dong, G. | 登録日 | 2020-08-13 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar. Plos Pathog., 17, 2021
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6T3M
| Thrombin in Complex with a D-Phe-Pro-p-phenol derivative | 分子名称: | (2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[(4-hydroxyphenyl)methyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hirudin variant-2, ... | 著者 | Ngo, K, Collins, C, Heine, A, Klebe, G. | 登録日 | 2019-10-11 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Thrombin in Complex with a D-Phe-Pro-p-phenol derivative To Be Published
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7YGI
| Crystal structure of p53 DBD domain in complex with azurin | 分子名称: | Azurin, Cellular tumor antigen p53, PHOSPHATE ION, ... | 著者 | Jiang, W.X, Zuo, J.Q, Hu, J.J, Chen, X.Q, Ma, L.X, Liu, Z, Xing, Q. | 登録日 | 2022-07-11 | 公開日 | 2023-02-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination. Commun Biol, 6, 2023
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6T54
| Thrombin in Complex with a D-Phe-Pro-2-bromothiophene Derivative | 分子名称: | (2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[(5-bromanylthiophen-2-yl)methyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Ngo, K, Abazi, N, Heine, A, Klebe, G. | 登録日 | 2019-10-15 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Thrombin in Complex with a D-Phe-Pro-2-bromothiophene Derivative To Be Published
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6QGD
| Structure of human Mcl-1 in complex with thienopyrimidine inhibitor | 分子名称: | 2-[(6-ethyl-5-phenyl-thieno[2,3-d]pyrimidin-4-yl)amino]-3-oxidanyl-propanoic acid, Maltose-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, ... | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | 登録日 | 2019-01-11 | 公開日 | 2019-06-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1. Acs Omega, 4, 2019
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7XQ7
| The complex structure of WT-Mpro | 分子名称: | 3C-like proteinase nsp5, SODIUM ION | 著者 | Sahoo, P, Lenka, D.R, Kumar, A. | 登録日 | 2022-05-06 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Acs Pharmacol Transl Sci, 6, 2023
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6TG8
| Crystal structure of the Kelch domain in complex with 11 amino acid peptide (model of the ETGE loop) | 分子名称: | Kelch-like ECH-associated protein 1, SODIUM ION, VAL-ILE-ASN-PRO-GLU-THR-GLY-GLU-GLN-ILE-GLN | 著者 | Kekez, I, Matic, S, Tomic, S, Matkovic-Calogovic, D. | 登録日 | 2019-11-15 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Binding of dipeptidyl peptidase III to the oxidative stress cell sensor Kelch-like ECH-associated protein 1 is a two-step process. J.Biomol.Struct.Dyn., 39, 2021
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7WBO
| Crystal structure of Sarcoplasmic Calcium-Binding Protein from Scylla paramamosain | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... | 著者 | Chen, Y, Jin, T, Liu, G. | 登録日 | 2021-12-17 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure Analysis of Sarcoplasmic-Calcium-Binding Protein: An Allergen in Scylla paramamosain. J.Agric.Food Chem., 71, 2023
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7A36
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5TY0
| 2.22 Angstrom Crystal Structure of N-terminal Fragment (residues 1-419) of Elongation Factor G from Legionella pneumophila. | 分子名称: | Elongation factor G, SODIUM ION, beta-D-glucopyranose | 著者 | Minasov, G, Wawrzak, Z, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-11-17 | 公開日 | 2016-11-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | 2.22 Angstrom Crystal Structure of N-terminal Fragment (residues 1-419) of Elongation Factor G from Legionella pneumophila. To Be Published
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6T52
| Thrombin in Complex with a D-Phe-Pro-imidazole derivative | 分子名称: | (2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[2-(1~{H}-imidazol-4-yl)ethyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Ngo, K, Abazi, N, Heine, A, Klebe, G. | 登録日 | 2019-10-15 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Thrombin in Complex with a D-Phe-Pro-imidazole derivative To Be Published
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7A0A
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7A2K
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7A2L
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4RWY
| Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Acharya, P, Luongo, T.S, Kwong, P.D. | 登録日 | 2014-12-08 | 公開日 | 2015-07-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.128 Å) | 主引用文献 | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell(Cambridge,Mass.), 161, 2015
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7A2J
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7A33
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7AE7
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7A2N
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7A2M
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7AC4
| Structure of insulin collected by rotation serial crystallography on a COC membrane at a synchrotron source | 分子名称: | Insulin, R-1,2-PROPANEDIOL, SODIUM ION | 著者 | Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. | 登録日 | 2020-09-09 | 公開日 | 2021-09-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Versatile microporous polymer-based supports for serial macromolecular crystallography. Acta Crystallogr D Struct Biol, 77, 2021
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7AAW
| Thioredoxin Reductase from Bacillus cereus | 分子名称: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Shoor, M, Gudim, I, Hersleth, H.-P, Hammerstad, M. | 登録日 | 2020-09-04 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Thioredoxin reductase from Bacillus cereus exhibits distinct reduction and NADPH-binding properties. Febs Open Bio, 11, 2021
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7ADS
| Orf virus Apoptosis inhibitor ORFV125 | 分子名称: | 1,2-ETHANEDIOL, Apoptosis inhibitor, CHLORIDE ION, ... | 著者 | Suraweera, C.D, Hinds, M.G, Kvansakul, M. | 登録日 | 2020-09-16 | 公開日 | 2021-10-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.22032046 Å) | 主引用文献 | Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis. Biochem.J., 477, 2020
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7Z9P
| The novel DNA binding mechanism of ridinilazole, a precision Clostridiodes difficile antibiotic | 分子名称: | DNA (5'-D(P*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G*(RID))-3'), Ridinilazole, SODIUM ION, ... | 著者 | Mason, S, Leonard, P.M. | 登録日 | 2022-03-21 | 公開日 | 2023-03-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic. Antimicrob.Agents Chemother., 67, 2023
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