5NYP
| |
6PEH
| |
5NYW
| Anbu (ancestral beta-subunit) from Yersinia bercovieri | 分子名称: | 1,2-ETHANEDIOL, AZIDE ION, CHLORIDE ION, ... | 著者 | Piasecka, A, Czapinska, H, Vielberg, M, Szczepanowski, R.H, Reed, S, Groll, M, Bochtler, M. | 登録日 | 2017-05-12 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers. J. Mol. Biol., 430, 2018
|
|
4ZZI
| SIRT1/Activator/Inhibitor Complex | 分子名称: | (3S)-1,3-dimethyl-N-[3-(1,3-oxazol-5-yl)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide, 4-(4-{2-[(methylsulfonyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide, NAD-dependent protein deacetylase sirtuin-1, ... | 著者 | Dai, H. | 登録日 | 2015-05-22 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7346 Å) | 主引用文献 | Crystallographic structure of a small molecule SIRT1 activator-enzyme complex. Nat Commun, 6, 2015
|
|
5OBD
| X-ray structure of the adduct formed upon reaction of ribonuclease A with the compound fac-[RuII(CO)3Cl2(N3-MIM), MIM=methyl-imidazole | 分子名称: | PHOSPHATE ION, Ribonuclease pancreatic, tris(oxidaniumylidynemethyl)-tris(oxidanyl)ruthenium | 著者 | Pontillo, N, Ferraro, G, Merlino, A. | 登録日 | 2017-06-26 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Ru-Based CO releasing molecules with azole ligands: interaction with proteins and the CO release mechanism disclosed by X-ray crystallography. Dalton Trans, 46, 2017
|
|
4UOY
| |
5O11
| |
5O19
| |
5O1E
| p53 cancer mutant Y220C im complex with compound MB577 | 分子名称: | 3-iodanyl-2-oxidanyl-5-prop-2-enoxy-4-pyrrol-1-yl-benzoic acid, Cellular tumor antigen p53, GLYCEROL, ... | 著者 | Joerger, A.C, Baud, M.G.J, Bauer, M.R, Fersht, A.R. | 登録日 | 2017-05-18 | 公開日 | 2018-05-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines. Eur J Med Chem, 152, 2018
|
|
5O1L
| Structure of Latex Clearing Protein LCP in the open state with bound imidazole | 分子名称: | (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, IMIDAZOLE, ... | 著者 | Ilcu, L, Roether, W, Birke, J, Brausemann, A, Einsle, O, Jendrossek, D. | 登録日 | 2017-05-18 | 公開日 | 2017-08-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Structural and Functional Analysis of Latex Clearing Protein (Lcp) Provides Insight into the Enzymatic Cleavage of Rubber. Sci Rep, 7, 2017
|
|
5A32
| Electron cryo-microscopy of Cowpea Mosaic Virus containing RNA-1 (CPMVb) | 分子名称: | RNA2 POLYPROTEIN | 著者 | Hesketh, E.L, Meshcheriakova, Y, Dent, K.C, Saxena, P, Thompson, R, Cockburn, J.J, Lomonossoff, G.P, Ranson, N.A. | 登録日 | 2015-05-27 | 公開日 | 2015-12-23 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Mechanisms of assembly and genome packaging in an RNA virus revealed by high-resolution cryo-EM. Nat Commun, 6, 2015
|
|
3LCU
| Crystal Structure of Antibiotic related Methyltransferase | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, Sisomicin-gentamicin resistance methylase Sgm | 著者 | Sivaraman, J, Husain, N. | 登録日 | 2010-01-11 | 公開日 | 2010-06-02 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases. Nucleic Acids Res., 2010
|
|
5A5D
| A complex of the synthetic siderophore analogue Fe(III)-5-LICAM with the CeuE periplasmic protein from Campylobacter jejuni | 分子名称: | ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, FE (III) ION, N,N'-pentane-1,5-diylbis(2,3-dihydroxybenzamide) | 著者 | Blagova, E, Hughes, A, Moroz, O.V, Raines, D.J, Wilde, E.J, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. | 登録日 | 2015-06-17 | 公開日 | 2016-06-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length. Sci Rep, 7, 2017
|
|
2BHU
| Crystal structure of Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, MALTOOLIGOSYLTREHALOSE TREHALOHYDROLASE, ... | 著者 | Timmins, J, Leiros, H.-K.S, Leonard, G, Leiros, I, McSweeney, S. | 登録日 | 2005-01-18 | 公開日 | 2005-03-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Crystal Structure of Maltooligosyltrehalose Trehalohydrolase from Deinococcus Radiodurans in Complex with Disaccharides J.Mol.Biol., 347, 2005
|
|
2BIA
| Radiation damage of the Schiff base in phosphoserine aminotransferase (structure G) | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Dubnovitsky, A.P, Ravelli, R.B.G, Popov, A.N, Papageorgiou, A.C. | 登録日 | 2005-01-20 | 公開日 | 2005-05-19 | 最終更新日 | 2019-05-22 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Strain Relief at the Active Site of Phosphoserine Aminotransferase Induced by Radiation Damage. Protein Sci., 14, 2005
|
|
5A5Q
| Crystal structure of human ATAD2 bromodomain in complex with 3-methyl- 8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one hydrochloride | 分子名称: | 1,2-ETHANEDIOL, 3-methyl-8-[(piperidin-4-yl)amino]-1,2-dihydro-1,7-naphthyridin-2-one, ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2, ... | 著者 | Chung, C, Bamborough, P, Demont, E. | 登録日 | 2015-06-20 | 公開日 | 2015-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Fragment-Based Discovery of Low-Micromolar Atad2 Bromodomain Inhibitors. J.Med.Chem., 58, 2015
|
|
5OCI
| Human Heat Shock Protein 90 bound to 6-Hydroxy-3-(3-methyl-benzyl)-1H-indazole-5-carboxylic acid methyl-(4-morpholin-4-yl-phenyl)-amide | 分子名称: | 6-Hydroxy-3-(3-methyl-benzyl)-1H-indazole-5-carboxylic acid methyl-(4-morpholin-4-yl-phenyl)-amide, Heat shock protein HSP 90-alpha | 著者 | Schuetz, D.A, Richter, L, Amaral, M, Grandits, M, Musil, D, Graedler, U, Frech, M, Ecker, G.F. | 登録日 | 2017-07-03 | 公開日 | 2018-05-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors. J. Med. Chem., 61, 2018
|
|
5OL1
| Crystal structure of an inactivated Ssp SICLOPPS intein with a CAFHPQ extein | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DNA polymerase III subunit alpha,DNA polymerase III subunit alpha, ... | 著者 | Kick, L.M, Schneider, S. | 登録日 | 2017-07-26 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | 主引用文献 | Mechanistic Insights into Cyclic Peptide Generation by DnaE Split-Inteins through Quantitative and Structural Investigation. Chembiochem, 18, 2017
|
|
5A9X
| Structure of GDP bound BipA | 分子名称: | GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE | 著者 | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G. | 登録日 | 2015-07-23 | 公開日 | 2015-08-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
5OL9
| Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain | 分子名称: | ACETATE ION, Transcription elongation factor, mitochondrial | 著者 | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | 登録日 | 2017-07-27 | 公開日 | 2017-10-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | 主引用文献 | Mechanism of Transcription Anti-termination in Human Mitochondria. Cell, 171, 2017
|
|
5OCO
| Discovery of small molecules binding to KRAS via high affinity antibody fragment competition method. | 分子名称: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, GTPase KRas, ... | 著者 | Cruz-Migoni, A, Ehebauer, M.T, Phillips, S.E.V, Quevedo, C.E, Rabbitts, T.H. | 登録日 | 2017-07-03 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment. Nat Commun, 9, 2018
|
|
4ZRR
| Crystal Structure of Monomeric Bacteriophytochrome mutant D207L Y263F at 1.5 A resolution Using a home source. | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome, ... | 著者 | Bhattacharya, S, Satyshur, K.A, Lehtivuori, H, Forest, K.T. | 登録日 | 2015-05-12 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor. Front Mol Biosci, 2, 2015
|
|
4U9H
| Ultra High Resolution Structure Of The Ni-R State Of [Nife]Hydrogenase From Desulufovibrio Vulgaris Miyazaki F | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE3-S4 CLUSTER, ... | 著者 | Ogata, H, Nishikawa, K, Lubitz, W. | 登録日 | 2014-08-06 | 公開日 | 2015-01-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | 主引用文献 | Hydrogens detected by subatomic resolution protein crystallography in a [NiFe] hydrogenase. Nature, 520, 2015
|
|
5OLC
| |
5WQ9
| |