PDB: 66724 件ウェブページステータス検索Chemie searchBIRD

---

6JSG	Crystal Structure of BACE1 in complex with N-{3-[(4S)-2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-5-chloropyridine-2-carboxamide 分子名称: Beta-secretase 1, GLYCEROL, IODIDE ION, ... 著者 Fujimoto, K, Matsuoka, E, Asada, N, Tadano, G, Yamamoto, T, Nakahara, K, Fuchino, K, Ito, H, Kanegawa, N, Moechars, D, Gijsen, H.J.M, Kusakabe, K.I. 登録日 2019-04-08 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-Based Design of Selective beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2. J.Med.Chem., 62, 2019
6JEC	Structure of a triple-helix region of human collagen type II 分子名称: human collagen type II 著者 Yang, X, Zhu, Y, Ye, S, Zhang, R. 登録日 2019-02-05 公開日 2020-02-05 実験手法 X-RAY DIFFRACTION (2.049 Å) 主引用文献 Structure of a triple-helix region of human collagen type II. To Be Published
6JKL	Structure of a triple-helix region of human collagen type II 分子名称: A triple-helix region of human collagen type II 著者 Yang, X, Zhu, Y, Ye, S, Zhang, R. 登録日 2019-03-01 公開日 2020-03-04 実験手法 X-RAY DIFFRACTION (2.148 Å) 主引用文献 Structure of a triple-helix region of human collagen type II. To Be Published
3Q0Q	Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREa 分子名称: 5'-R(UP*GP*UP*AP*AP*AP*UP*A)-3', Pumilio homolog 2 著者 Lu, G, Hall, T.M.T. 登録日 2010-12-15 公開日 2011-03-16 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure, 19, 2011
3Q0P	Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with hunchback NRE 分子名称: 5'-R(UP*GP*UP*AP*UP*AP*UP*A)-3', CHLORIDE ION, Pumilio homolog 1 著者 Lu, G, Hall, T.M.T. 登録日 2010-12-15 公開日 2011-03-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure, 19, 2011
4KQ3	Crystal structure of Anti-IL-17A antibody CNTO3186 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CNTO3186 heavy chain, ... 著者 Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. 登録日 2013-05-14 公開日 2014-03-26 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural evidence for a constrained conformation of short CDR-L3 in antibodies. Proteins, 82, 2014
3OAK	Crystal structure of a Spn1 (Iws1)-Spt6 complex 分子名称: Transcription elongation factor SPT6, Transcription factor IWS1 著者 McDonald, S.M, Close, D, Hill, C.P. 登録日 2010-08-05 公開日 2010-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure and biological importance of the spn1-spt6 interaction, and its regulatory role in nucleosome binding. Mol.Cell, 40, 2010
3LUD	Crystal structure of MID domain from hAGO2 in complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Protein argonaute-2 著者 Frank, F, Sonenberg, N, Nagar, B. 登録日 2010-02-17 公開日 2010-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.095 Å) 主引用文献 Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature, 465, 2010
6LUP	Crystal structure of shark MHC CLASS I for 2.3 angstrom 分子名称: Beta-2-microglobulin, MHC class I protein, PHE-ALA-ASN-PHE-PHE-ILE-ARG-GLY-LEU 著者 Wu, Y, Xia, C. 登録日 2020-01-30 公開日 2021-04-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 The Structure of a Peptide-Loaded Shark MHC Class I Molecule Reveals Features of the Binding between beta 2 -Microglobulin and H Chain Conserved in Evolution. J Immunol., 2021
6LUO	Structure of nurse shark beta-2-microglobulin 分子名称: Beta-2-microglobulin 著者 Xia, C, Wu, Y. 登録日 2020-01-30 公開日 2021-04-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 The Structure of a Peptide-Loaded Shark MHC Class I Molecule Reveals Features of the Binding between beta 2 -Microglobulin and H Chain Conserved in Evolution. J Immunol., 2021
3LK9	DNA polymerase beta with a gapped DNA substrate and dTMP(CF2)P(CF2)P 分子名称: 5'-O-[(R)-{[(R)-[difluoro(phosphono)methyl](hydroxy)phosphoryl](difluoro)methyl}(hydroxy)phosphoryl]thymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Zibinsky, M, Surya Prakash, G.K, Upton, T.G, Kashemirov, B.A, McKenna, C.E, Oertell, K, Goodman, M.F, Batra, V.K, Pedersen, L.C, Beard, W.A, Wilson, S.H. 登録日 2010-01-27 公開日 2011-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Proc.Natl.Acad.Sci.USA, 107, 2010
3PSK	Crystal Structure of the Spt6 Tandem SH2 Domain from Saccharomyces cerevisiae, Form Native Spt6 (1247-1451) 分子名称: SULFATE ION, Transcription elongation factor SPT6 著者 Close, D, Hill, C.P. 登録日 2010-12-01 公開日 2011-03-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J.Mol.Biol., 408, 2011
6MIN	Crystal structure of Taf14 YEATS domain G82A mutant in complex with histone H3K9cr 分子名称: Histone H3K9cr, Transcription initiation factor TFIID subunit 14 著者 Klein, B.J, Andrews, F.H, Kutateladze, T.G. 登録日 2018-09-19 公開日 2018-11-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun, 9, 2018
6MIU	Crystal structure of p62 ZZ domain in complex with Arg-Glu peptide 分子名称: Sequestosome-1, Arg-Glu peptide chimera, ZINC ION 著者 Ahn, J, Zhang, Y, Kutateladze, T.G. 登録日 2018-09-20 公開日 2018-10-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 ZZ-dependent regulation of p62/SQSTM1 in autophagy. Nat Commun, 9, 2018
6MJT	Azurin 122F/124W/126Re 分子名称: (1,10 PHENANTHROLINE)-(TRI-CARBON MONOXIDE) RHENIUM (I), Azurin, COPPER (II) ION 著者 Takematsu, K, Zalis, S, Gray, H.B, Vlcek, A, Winkler, J.R, Williamson, H, Kaiser, J.T, Heyda, J, Hollas, D. 登録日 2018-09-21 公開日 2019-02-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.893 Å) 主引用文献 Two Tryptophans Are Better Than One in Accelerating Electron Flow through a Protein. ACS Cent Sci, 5, 2019
6MJR	Azurin 122W/124F/126Re 分子名称: (1,10 PHENANTHROLINE)-(TRI-CARBON MONOXIDE) RHENIUM (I), Azurin, COPPER (II) ION 著者 Takematsu, K, Zalis, S, Gray, H.B, Vlcek, A, Winkler, J.R, Williamson, H, Kaiser, J.T, Heyda, J, Hollas, D. 登録日 2018-09-21 公開日 2019-02-20 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.012 Å) 主引用文献 Two Tryptophans Are Better Than One in Accelerating Electron Flow through a Protein. ACS Cent Sci, 5, 2019
3Q0R	Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREb 分子名称: 5'-R(UP*GP*UP*AP*GP*AP*UP*A)-3', Pumilio homolog 2 著者 Lu, G, Hall, T.M.T. 登録日 2010-12-15 公開日 2011-03-16 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure, 19, 2011
4KLE	DNA polymerase beta matched reactant complex with Mg2+, 10 s 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), ... 著者 Freudenthal, B.D, Beard, W.A, Shock, D.D, Wilson, S.H. 登録日 2013-05-07 公開日 2013-07-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Observing a DNA polymerase choose right from wrong. Cell(Cambridge,Mass.), 154, 2013
6IXZ	X-ray structure of sortase C from Clostridium perfringens SM101 分子名称: Sortase family protein 著者 Kamitori, S, Tamai, E. 登録日 2018-12-12 公開日 2019-08-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structures of major pilins in Clostridium perfringens demonstrate dynamic conformational change. Acta Crystallogr D Struct Biol, 75, 2019
6JIK	Aspergillus fumigatus Rho1 GsGTP 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho GTPase Rho1 著者 Bartual, S.G, Van Aalten, D.M.F. 登録日 2019-02-22 公開日 2020-09-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Aspergillus fumigatus Rho1 gSGTP complex To Be Published
6MIO	Crystal structure of Taf14 YEATS domain in complex with histone H3K9pr 分子名称: Histone H3K9pr, Transcription initiation factor TFIID subunit 14 著者 Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G. 登録日 2018-09-19 公開日 2018-11-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun, 9, 2018
6MKQ	Carbapenemase VCC-1 bound to avibactam 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase 著者 Mark, B.L, Vadlamani, G. 登録日 2018-09-26 公開日 2019-01-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular Basis for the Potent Inhibition of the Emerging Carbapenemase VCC-1 by Avibactam. Antimicrob. Agents Chemother., 63, 2019
6ML6	ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4 with a CpA 5mC Modification) 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*(5CM)P*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*CP*GP*AP*AP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*TP*TP*CP*GP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ... 著者 Horton, J.R, Cheng, X, Ren, R. 登録日 2018-09-26 公開日 2019-07-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
6MP0	Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with the TRP1-M9 peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, TRP1-M9 peptide, Beta-2-microglobulin,H-2 class I histocompatibility antigen, ... 著者 Clancy-Thompson, E, Devlin, C.A, Birnbaum, M.E, Dougan, S.K. 登録日 2018-10-05 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+T Cell-Effector Responses. Cancer Immunol Res, 6, 2018
3Q0O	Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with erk2 NRE 分子名称: 5'-R(UP*GP*UP*AP*CP*AP*UP*C)-3', Pumilio homolog 1 著者 Lu, G, Hall, T.M.T. 登録日 2010-12-15 公開日 2011-03-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.804 Å) 主引用文献 Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure, 19, 2011

<435436437438439440441442443444445446447448449450>