PDB: 10704 件ウェブページステータス検索Chemie searchBIRD

---

8A5X	Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with MM1373 分子名称: 4-azanyl-7-[3-(hydroxymethyl)phenyl]quinazoline-6-carboxamide, Phosphatidylinositol 4-kinase type 2-beta,Endolysin 著者 Klima, M, Boura, E. 登録日 2022-06-16 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorg.Med.Chem.Lett., 76, 2022
3E6I	Human cytochrome P450 2E1 in complex with the inhibitor indazole 分子名称: 1H-indazole, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE 著者 Porubsky, P.R, Meneely, K.M, Scott, E.E. 登録日 2008-08-15 公開日 2008-09-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of human cytochrome P450 2E1: insights into the binding of inhibitors and both small molecular weight and fatty acid substrates. J.Biol.Chem., 283, 2008
3F49	Anion-triggered Engineered Subtilisin SUBT_BACAM 分子名称: SODIUM ION, Subtilisin BPN 著者 Gallagher, D.T, Bryan, P.N. 登録日 2008-10-31 公開日 2008-12-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Anion-triggered Engineered Subtilisin SUBT_BACAM To be Published
3GCL	Mode of ligand binding and assignment of subsites in mammalian peroxidases: crystal structure of lactoperoxidase complexes with acetyl salycylic acid, salicylhydroxamic acid and benzylhydroxamic acid 分子名称: 2-(ACETYLOXY)BENZOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Singh, A.K, Singh, N, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. 登録日 2009-02-22 公開日 2009-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Binding modes of aromatic ligands to mammalian heme peroxidases with associated functional implications: crystal structures of lactoperoxidase complexes with acetylsalicylic acid, salicylhydroxamic acid, and benzylhydroxamic acid J.Biol.Chem., 284, 2009
3DKE	Polar and non-polar cavities in phage T4 lysozyme 分子名称: 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AZIDE ION, ... 著者 Liu, L.J, Matthews, B.W. 登録日 2008-06-24 公開日 2008-11-25 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Use of experimental crystallographic phases to examine the hydration of polar and nonpolar cavities in T4 lysozyme Proc.Natl.Acad.Sci.USA, 105, 2008
3FO5	Human START domain of Acyl-coenzyme A thioesterase 11 (ACOT11) 分子名称: 3,3',3''-phosphanetriyltripropanoic acid, CHLORIDE ION, GLYCEROL, ... 著者 Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van-Den-Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Shueler, H, Structural Genomics Consortium (SGC) 登録日 2008-12-27 公開日 2009-02-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
3FU7	Melanocarpus albomyces laccase crystal soaked (4 sec) with 2,6-dimethoxyphenol 分子名称: 2,6-dimethoxycyclohexa-2,5-diene-1,4-dione, 2,6-dimethoxyphenol, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kallio, J.P, Hakulinen, N, Rouvinen, J. 登録日 2009-01-14 公開日 2009-09-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structure Function Studies of a Melanocarpus albomyces Laccase Suggest a Pathway for Oxidation of Phenolic Compounds. J.Mol.Biol., 392, 2009
3GFR	Structure of YhdA, D137L variant 分子名称: FLAVIN MONONUCLEOTIDE, FMN-dependent NADPH-azoreductase 著者 Staunig, N, Gruber, K. 登録日 2009-02-27 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase Febs J., 276, 2009
3FYG	CRYSTAL STRUCTURE OF TETRADECA-(3-FLUOROTYROSYL)-GLUTATHIONE S-TRANSFERASE 分子名称: (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, MU CLASS TETRADECA-(3-FLUOROTYROSYL)-GLUTATHIONE S-TRANSFERASE OF ISOENZYME 著者 Xiao, G, Parsons, J.F, Armstrong, R.N, Gilliland, G.L. 登録日 1997-08-07 公開日 1999-06-01 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformational changes in the crystal structure of rat glutathione transferase M1-1 with global substitution of 3-fluorotyrosine for tyrosine. J.Mol.Biol., 281, 1998
3FU8	Melanocarpus albomyces laccase crystal soaked (10 sec) with 2,6-dimethoxyphenol 分子名称: 2,6-dimethoxyphenol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kallio, J.P, Hakulinen, N, Rouvinen, J. 登録日 2009-01-14 公開日 2009-09-22 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Function Studies of a Melanocarpus albomyces Laccase Suggest a Pathway for Oxidation of Phenolic Compounds. J.Mol.Biol., 392, 2009
3GFQ	Structure of YhdA, K109L variant 分子名称: FLAVIN MONONUCLEOTIDE, FMN-dependent NADPH-azoreductase 著者 Staunig, N, Gruber, K. 登録日 2009-02-27 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.996 Å) 主引用文献 A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase Febs J., 276, 2009
3GFS	Structure of YhdA, K109D/D137K variant 分子名称: FLAVIN MONONUCLEOTIDE, FMN-dependent NADPH-azoreductase 著者 Staunig, N, Gruber, K. 登録日 2009-02-27 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase Febs J., 276, 2009
3FF0	Crystal structure of a phenazine biosynthesis-related protein (phzb2) from pseudomonas aeruginosa at 1.90 A resolution 分子名称: GLYCEROL, Phenazine biosynthesis protein phzB 2, UNKNOWN LIGAND 著者 Joint Center for Structural Genomics (JCSG) 登録日 2008-12-01 公開日 2008-12-16 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of protein PhzB2 with cystatin-like fold and unknown function in phenazine biosynthesis (NP_250591.1) from PSEUDOMONAS AERUGINOSA at 1.90 A resolution To be published
3GUR	Crystal Structure of mu class glutathione S-transferase (GSTM2-2) in complex with glutathione and 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) 分子名称: 1,2-ETHANEDIOL, GLUTATHIONE, Glutathione S-transferase Mu 2, ... 著者 Federici, L, Lo Sterzo, C, Di Matteo, A, Scaloni, F, Federici, G, Caccuri, A.M. 登録日 2009-03-30 公開日 2009-10-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases Cancer Res., 69, 2009
3H4K	Crystal structure of the wild type Thioredoxin glutatione reductase from Schistosoma mansoni in complex with auranofin 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GOLD ION, ... 著者 Angelucci, F, Dimastrogiovanni, D, Miele, A.E, Boumis, G, Brunori, M, Bellelli, A. 登録日 2009-04-20 公開日 2009-08-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J.Biol.Chem., 284, 2009
3DKH	L559A mutant of Melanocarpus albomyces laccase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Hakulinen, N, Rouvinen, J. 登録日 2008-06-25 公開日 2009-07-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure Febs J., 276, 2009
3GPH	Human cytochrome P450 2E1 in complex with omega-imidazolyl-decanoic acid 分子名称: 10-(1H-imidazol-1-yl)decanoic acid, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE 著者 Porubsky, P.R, Battaile, K.P, Scott, E.E. 登録日 2009-03-23 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode. J.Biol.Chem., 285, 2010
3E4E	Human cytochrome P450 2E1 in complex with the inhibitor 4-methylpyrazole 分子名称: 4-methyl-1H-pyrazole, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE 著者 Meneely, K.M, Porubsky, P.R, Scott, E.E. 登録日 2008-08-11 公開日 2008-09-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of human cytochrome P450 2E1: insights into the binding of inhibitors and both small molecular weight and fatty acid substrates. J.Biol.Chem., 283, 2008
3GST	STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE 分子名称: (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, GLUTATHIONE S-TRANSFERASE, SULFATE ION 著者 Ji, X, Ammon, H.L, Armstrong, R.N, Gilliland, G.L. 登録日 1993-06-07 公開日 1993-10-31 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene. Biochemistry, 33, 1994
3GWR	Crystal structure of Putative calcium/calmodulin-dependent protein kinase type II association domain (YP_315894.1) from THIOBACILLUS DENITRIFICANS ATCC 25259 at 2.00 A resolution 分子名称: Putative calcium/calmodulin-dependent protein kinase type II association domain, TETRAETHYLENE GLYCOL, UNKNOWN LIGAND 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-04-01 公開日 2009-04-14 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure of Putative calcium/calmodulin-dependent protein kinase type II association domain (YP_315894.1) from THIOBACILLUS DENITRIFICANS ATCC 25259 at 2.00 A resolution To be published
3H6K	Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an Ortho-chlro-sulfonyl-piperazine Inhibitor 分子名称: 3-chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)benzamide, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Bard, J, Svenson, K. 登録日 2009-04-23 公開日 2009-12-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.187 Å) 主引用文献 Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J.Med.Chem., 52, 2009
3GTU	LIGAND-FREE HETERODIMERIC HUMAN GLUTATHIONE S-TRANSFERASE M2-3 (EC 2.5.1.18), MONOCLINIC CRYSTAL FORM 分子名称: GLUTATHIONE S-TRANSFERASE 著者 Patskovsky, Y.V, Patskovska, L.N, Listowsky, I. 登録日 1998-07-29 公開日 1999-07-29 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases. Biochemistry, 38, 1999
3HIG	Crystal structure of human diamine oxidase in complex with the inhibitor berenil 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive amine oxidase, BERENIL, ... 著者 McGrath, A.P, Guss, J.M. 登録日 2009-05-19 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure and inhibition of human diamine oxidase Biochemistry, 48, 2009
3HFG	Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an Sulfonyl-piperazine Inhibitor 分子名称: (2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(1H-1,2,4-triazol-1-yl)phenyl]sulfonyl}piperazine, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Bard, J, Svenson, K. 登録日 2009-05-11 公開日 2009-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J.Med.Chem., 52, 2009
5OQM	STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Urlaub, H, Cramer, P. 登録日 2017-08-13 公開日 2018-05-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017

<414415416417418419420421422423424425426427428429>