PDB: 85 件ウェブページステータス検索Chemie searchBIRD

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6X9I	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*G)-R(P*(PYO))-D(P*GP*GP*CP*CP*TP*C)-3'), ... 著者 Pathuri, S, Horton, J.R, Cheng, X. 登録日 2020-06-02 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
6X9K	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3685032A 分子名称: (2R)-2-{[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]sulfanyl}-2-phenylacetamide, 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), ... 著者 Pathuri, S, Horton, J.R, Cheng, X. 登録日 2020-06-02 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
6X9J	Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3830052 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*G)-R(P*(PYO))-D(P*GP*GP*CP*CP*TP*C)-3'), ... 著者 Pathuri, S, Horton, J.R, Cheng, X. 登録日 2020-06-02 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
7TJF	S. cerevisiae ORC bound to 84 bp ARS1 DNA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA, 84 bp ARS1, ... 著者 Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. 登録日 2022-01-16 公開日 2023-01-18 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
7TJK	S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with docked Orc6 N-terminal domain 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... 著者 Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. 登録日 2022-01-16 公開日 2022-10-05 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
7TJJ	S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with docked Orc6 N-terminal domain 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... 著者 Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. 登録日 2022-01-16 公開日 2022-10-05 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
7VDV	The overall structure of human chromatin remodeling PBAF-nucleosome complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ... 著者 Chen, Z.C, Chen, K.J, Yuan, J.J. 登録日 2021-09-07 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of human chromatin-remodelling PBAF complex bound to a nucleosome. Nature, 605, 2022
7UBU	Crystal structure of ZMET2 in complex with hemimethylated CAG DNA and a histone H3Kc9me2 peptide 分子名称: 5MC SSDNA, C49 SSDNA, DNA (cytosine-5)-methyltransferase 1, ... 著者 Fang, J, Song, J. 登録日 2022-03-15 公開日 2022-06-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Mechanistic basis for maintenance of CHG DNA methylation in plants. Nat Commun, 13, 2022
7TJI	S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with flexible Orc6 N-terminal domain 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... 著者 Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. 登録日 2022-01-16 公開日 2022-10-05 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
7TJH	S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... 著者 Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. 登録日 2022-01-16 公開日 2022-10-05 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022

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