4U92
 
 | | Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad | | 分子名称: | BARIUM ION, DNA (5'-D(*CP*CP*AP*KP*GP*CP*GP*TP*GP*G)-3'), MAGNESIUM ION | | 著者 | Paukstelis, P.J, Zhang, D, Huang, T, Lukeman, P. | | 登録日 | 2014-08-05 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad.
Nucleic Acids Res., 42, 2014
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5HGJ
 | | Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Brown, K.L, Banerjee, S, Feigley, A, Abe, H, Blackwell, T, Zent, R, Pozzi, A, Hudson, B.H. | | 登録日 | 2016-01-08 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | Salt-bridge modulates differential calcium-mediated ligand binding to integrin alpha 1- and alpha 2-I domains.
Sci Rep, 8, 2018
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5WT4
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1QKO
 | | HIGH RESOLUTION X-RAY STRUCTURE OF AN EARLY INTERMEDIATE IN THE BACTERIORHODOPSIN PHOTOCYCLE | | 分子名称: | BACTERIORHODOPSIN, RETINAL | | 著者 | Edman, K, Nollert, P, Royant, A, Belrhali, H, Pebay-Peyroula, E, Hajdu, J, Neutze, R, Landau, E.M. | | 登録日 | 1999-07-30 | | 公開日 | 1999-10-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High Resolution X-Ray Structure of an Early Intermediate in the Bacteriorhodopsin Photocycle
Nature, 401, 1999
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5NJ8
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1GWR
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1CHW
 | | CHALCONE SYNTHASE FROM ALFALFA COMPLEXED WITH HEXANOYL-COA | | 分子名称: | HEXANOYL-COENZYME A, PROTEIN (CHALCONE SYNTHASE) | | 著者 | Ferrer, J.-L, Jez, J, Bowman, M.E, Dixon, R, Noel, J.P. | | 登録日 | 1999-03-30 | | 公開日 | 1999-08-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
Nat.Struct.Biol., 6, 1999
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1NSP
 | | MECHANISM OF PHOSPHATE TRANSFER BY NUCLEOSIDE DIPHOSPHATE KINASE: X-RAY STRUCTURES OF A PHOSPHO-HISTIDINE INTERMEDIATE OF THE ENZYMES FROM DROSOPHILA AND DICTYOSTELIUM | | 分子名称: | NUCLEOSIDE DIPHOSPHATE KINASE | | 著者 | Janin, J, Morera, S, Chiadmi, M, Lebras, G, Lascu, I. | | 登録日 | 1995-04-18 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mechanism of phosphate transfer by nucleoside diphosphate kinase: X-ray structures of the phosphohistidine intermediate of the enzymes from Drosophila and Dictyostelium.
Biochemistry, 34, 1995
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1H4G
 | | Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre | | 分子名称: | SULFATE ION, XYLANASE, beta-D-xylopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-xylopyranose | | 著者 | Sabini, E, Wilson, K.S, Danielsen, S, Schulein, M, Davies, G.J. | | 登録日 | 2001-05-11 | | 公開日 | 2002-05-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase.
Chem.Biol., 6, 1999
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1CML
 | | CHALCONE SYNTHASE FROM ALFALFA COMPLEXED WITH MALONYL-COA | | 分子名称: | MALONYL-COENZYME A, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), PROTEIN (CHALCONE SYNTHASE), ... | | 著者 | Ferrer, J.-L, Jez, J, Bowman, M.E, Dixon, R, Noel, J.P. | | 登録日 | 1999-03-30 | | 公開日 | 1999-08-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
Nat.Struct.Biol., 6, 1999
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1Q2R
 | | Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate | | 分子名称: | 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase, RNA (5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(N)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3'), ... | | 著者 | Xie, W, Liu, X, Huang, R.H. | | 登録日 | 2003-07-25 | | 公開日 | 2003-09-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nat.Struct.Biol., 10, 2003
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6FOF
 | | Crystal structure of a crystallized variant of h-Gal3: Gal-3[NTS/VII-IX] | | 分子名称: | Galectin-3,Galectin-3, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Romero, A, Flores-Ibarra, A, Medrano, F.J. | | 登録日 | 2018-02-07 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallization of a human galectin-3 variant with two ordered segments in the shortened N-terminal tail.
Sci Rep, 8, 2018
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1AVF
 | | ACTIVATION INTERMEDIATE 2 OF HUMAN GASTRICSIN FROM HUMAN STOMACH | | 分子名称: | GASTRICSIN, SODIUM ION | | 著者 | Khan, A.R, Cherney, M.M, Tarasova, N.I, James, M.N.G. | | 登録日 | 1997-09-16 | | 公開日 | 1998-02-25 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin.
Nat.Struct.Biol., 4, 1997
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1CGZ
 | | CHALCONE SYNTHASE FROM ALFALFA COMPLEXED WITH RESVERATROL | | 分子名称: | PROTEIN (CHALCONE SYNTHASE), RESVERATROL | | 著者 | Ferrer, J.-L, Jez, J, Bowman, M.E, Dixon, R, Noel, J.P. | | 登録日 | 1999-03-26 | | 公開日 | 1999-08-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
Nat.Struct.Biol., 6, 1999
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1TZS
 | | Crystal Structure of an activation intermediate of Cathepsin E | | 分子名称: | 23-mer peptide from PelB-IgG kappa light chain fusion protein, Cathepsin E, activation peptide from Cathepsin E | | 著者 | Ostermann, N, Gerhartz, B, Worpenberg, S, Trappe, J, Eder, J. | | 登録日 | 2004-07-12 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of an activation intermediate of cathepsin e
J.Mol.Biol., 342, 2004
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6KLR
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6EE8
 | | Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter | | 分子名称: | DNA (60-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | | 登録日 | 2018-08-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | | 主引用文献 | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
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5V6Y
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2YLZ
 | | SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: Met446Gly MUTANT | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, PHENYLACETONE MONOOXYGENASE, SULFATE ION | | 著者 | Orru, R, Dudek, H.M, Martinoli, C, Torres Pazmino, D.E, Royant, A, Weik, M, Fraaije, M.W, Mattevi, A. | | 登録日 | 2011-06-06 | | 公開日 | 2011-06-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Snapshots of Enzymatic Baeyer-Villiger Catalysis: Oxygen Activation and Intermediate Stabilization.
J.Biol.Chem., 286, 2011
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2HQU
 | | Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | | 著者 | Barabas, O, Varga, B, Vertessy, B.G. | | 登録日 | 2006-07-19 | | 公開日 | 2007-07-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase.
Febs Lett., 581, 2007
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1XT3
 | | Structure Basis of Venom Citrate-Dependent Heparin Sulfate-Mediated Cell Surface Retention of Cobra Cardiotoxin A3 | | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CITRIC ACID, Cytotoxin 3 | | 著者 | Lee, S.-C, Guan, H.-H, Wang, C.-H, Huang, W.-N, Chen, C.-J, Wu, W.-G. | | 登録日 | 2004-10-21 | | 公開日 | 2004-12-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of citrate-dependent and heparan sulfate-mediated cell surface retention of cobra cardiotoxin A3
J.Biol.Chem., 280, 2005
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1JCL
 | | OBSERVATION OF COVALENT INTERMEDIATES IN AN ENZYME MECHANISM AT ATOMIC RESOLUTION | | 分子名称: | 1-HYDROXY-PENTANE-3,4-DIOL-5-PHOSPHATE, DEOXYRIBOSE-PHOSPHATE ALDOLASE | | 著者 | Heine, A, DeSantis, G, Luz, J.G, Mitchell, M, Wong, C.-H, Wilson, I.A. | | 登録日 | 2001-06-09 | | 公開日 | 2001-10-31 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Observation of covalent intermediates in an enzyme mechanism at atomic resolution.
Science, 294, 2001
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4JY9
 | | X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters | | 分子名称: | CHAPSO, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Nicolet, Y, Rohac, R, Martin, L, Fontecilla-Camps, J.C. | | 登録日 | 2013-03-29 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters.
Proc.Natl.Acad.Sci.USA, 110, 2013
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1RF4
 | | Structural Studies of Streptococcus pneumoniae EPSP Synthase, Tetrahedral intermediate Bound State | | 分子名称: | (3R,4S,5R)-5-{[(1R)-1-CARBOXY-2-FLUORO-1-(PHOSPHONOOXY)ETHYL]OXY}-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 5-enolpyruvylshikimate-3-phosphate synthase | | 著者 | Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C. | | 登録日 | 2003-11-07 | | 公開日 | 2004-02-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
Mol.Microbiol., 51, 2004
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1KPM
 | | First Structural Evidence of a Specific Inhibition of Phospholipase A2 by Vitamin E and its Implications in Inflammation: Crystal Structure of the Complex Formed between Phospholipase A2 and Vitamin E at 1.8 A Resolution. | | 分子名称: | ACETIC ACID, Phospholipase A2, VITAMIN E | | 著者 | Chandra, V, Jasti, J, Kaur, P, Betzel, C, Srinivasan, A, Singh, T.P. | | 登録日 | 2002-01-01 | | 公開日 | 2002-07-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | First Structural Evidence of a Specific Inhibition of Phospholipase A2 by alpha-Tocopherol (Vitamin E) and its
Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and
alpha-Tocopherol at 1.8 A Resolution
J.Mol.Biol., 320, 2002
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