5IA5
 
 | | Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with golvatinib (E7050) | | 分子名称: | 1,2-ETHANEDIOL, Ephrin type-A receptor 2, golvatinib | | 著者 | Kudlinzki, D, Linhard, V.L, Gande, S.L, Sreeramulu, S, Saxena, K, Heinzlmeir, S, Medard, G, Kuester, B, Schwalbe, H. | | 登録日 | 2016-02-21 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.776 Å) | | 主引用文献 | Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.
ACS Chem. Biol., 11, 2016
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4GLF
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4PNF
 | | Glutathione S-Transferase from Drosophila melanogaster - isozyme E6 | | 分子名称: | GLUTATHIONE, RE21095p | | 著者 | Scian, M, Le Trong, I, Mannervik, B, Atkins, W.M, Stenkamp, R.E. | | 登録日 | 2014-05-23 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Comparison of epsilon- and delta-class glutathione S-transferases: the crystal structures of the glutathione S-transferases DmGSTE6 and DmGSTE7 from Drosophila melanogaster.
Acta Crystallogr.,Sect.D, 71, 2015
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5AAQ
 | | TBK1 recruitment to cytosol-invading Salmonella induces anti- bacterial autophagy | | 分子名称: | CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2, ZINC ION | | 著者 | Thurston, T.L, Allen, M.D, Ravenhill, B, Karpiyevitch, M, Bloor, S, Kaul, A, Matthews, S, Komander, D, Holden, D, Bycroft, M, Randow, F. | | 登録日 | 2015-07-28 | | 公開日 | 2016-07-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Recruitment of Tbk1 to Cytosol-Invading Salmonella Induces Wipi2-Dependent Antibacterial Autophagy.
Embo J., 35, 2016
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3DEV
 | | Crystal structure of SH1221 protein from Staphylococcus haemolyticus, Northeast Structural Genomics Consortium Target ShR87 | | 分子名称: | MAGNESIUM ION, SH1221, SULFATE ION | | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-06-10 | | 公開日 | 2008-08-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of SH1221 protein from Staphylococcus haemolyticus, Northeast Structural Genomics Consortium Target ShR87
To be Published
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4WAI
 | | Structural characterization of the late competence protein ComFB from Bacillus subtilis. | | 分子名称: | ComF operon protein 2, ZINC ION | | 著者 | Sysoeva, T.A, Bane, L.B, Xiao, D, Gaudet, R, Burton, B.M. | | 登録日 | 2014-08-29 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.427 Å) | | 主引用文献 | Structural characterization of the late competence protein ComFB from Bacillus subtilis.
Biosci.Rep., 35, 2015
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3MMJ
 | | Structure of the PTP-like phytase from Selenomonas ruminantium in complex with myo-inositol hexakisphosphate | | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | | 登録日 | 2010-04-20 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Substrate binding in protein-tyrosine phosphatase-like inositol polyphosphatases.
J.Biol.Chem., 287, 2012
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3MPR
 | | Crystal Structure of endonuclease/exonuclease/phosphatase family protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR318A | | 分子名称: | ACETIC ACID, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kuzin, A, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-04-27 | | 公開日 | 2010-05-26 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target BtR318A
To be Published
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3DHI
 | | Crystal Structure of Reduced Toluene 4-Monoxygenase Hydroxylase Complexed with Effector Protein | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, FE (III) ION, ... | | 著者 | Bailey, L.J, Mccoy, J.G, Phillips Jr, G.N, Fox, B.G. | | 登録日 | 2008-06-17 | | 公開日 | 2008-12-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Structural consequences of effector protein complex formation in a diiron hydroxylase.
Proc.Natl.Acad.Sci.USA, 105, 2008
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5ILP
 | | H64Q sperm whale myoglobin with a Fe-tolyl moiety | | 分子名称: | GLYCEROL, Myoglobin, SULFATE ION, ... | | 著者 | Wang, B, Thomas, L.M, Richter-Addo, G.B. | | 登録日 | 2016-03-04 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Organometallic myoglobins: Formation of Fe-carbon bonds and distal pocket effects on aryl ligand conformations.
J. Inorg. Biochem., 164, 2016
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5A22
 | | Structure of the L protein of vesicular stomatitis virus from electron cryomicroscopy | | 分子名称: | VESICULAR STOMATITIS VIRUS L POLYMERASE, ZINC ION | | 著者 | Liang, B, Li, Z, Jenni, S, Rameh, A.A, Morin, B.M, Grant, T, Grigorieff, N, Harrison, S.C, Whelan, S.P.J. | | 登録日 | 2015-05-06 | | 公開日 | 2015-08-19 | | 最終更新日 | 2019-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Cell(Cambridge,Mass.), 162, 2015
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4GVJ
 | | Tyk2 (JH1) in complex with adenosine di-phosphate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Non-receptor tyrosine-protein kinase TYK2 | | 著者 | Liang, J, Abbema, A.V, Bao, L, Barrett, K, Beresini, M, Berezhkovskiy, L, Blair, W, Chang, C, Driscoll, J, Eigenbrot, C, Ghilardi, N, Gibbons, P, Halladay, J, Johnson, A, Kohli, P.B, Lai, Y, Liimatta, M, Mantik, P, Menghrajani, K, Murray, J, Sambrone, A, Shao, Y, Shia, S, Shin, Y, Smith, J, Sohn, S, Stanley, M, Tsui, V, Ultsch, M, Wu, L, Zhang, B, Magnuson, S. | | 登録日 | 2012-08-30 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Lead identification of novel and selective TYK2 inhibitors.
Eur.J.Med.Chem., 67, 2013
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5A58
 | | The structure of GH101 D764N mutant from Streptococcus pneumoniae TIGR4 in complex with serinyl T-antigen | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CITRIC ACID, ... | | 著者 | Gregg, K.J, Suits, M.D.L, Deng, L, Vocadlo, D.J, Boraston, A.B. | | 登録日 | 2015-06-16 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights Into its Mechanism.
J.Biol.Chem., 290, 2015
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7SRR
 | | 5-HT2B receptor bound to LSD in complex with heterotrimeric mini-Gq protein obtained by cryo-electron microscopy (cryoEM) | | 分子名称: | (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 2B, G protein subunit q (Gi2-mini-Gq chimera), ... | | 著者 | Barros-Alvarez, X, Kim, K, Panova, O, Cao, C, Roth, B.L, Skiniotis, G. | | 登録日 | 2021-11-08 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Neuron, 110, 2022
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5O2T
 | | Human KRAS in complex with darpin K27 | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase KRas, MAGNESIUM ION, ... | | 著者 | Debreczeni, J.E, Guillard, S, Kolasinska-Zwierz, P, Breed, J, Zhang, J, Bery, N, Marwood, R, Tart, J, Stocki, P, Mistry, B, Phillips, C, Rabbitts, T, Jackson, R, Minter, R. | | 登録日 | 2017-05-22 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange.
Nat Commun, 8, 2017
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4U3O
 | | Octameric RNA duplex soaked in manganese(II)chloride | | 分子名称: | MANGANESE (II) ION, RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3') | | 著者 | Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O. | | 登録日 | 2014-07-22 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
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2RO3
 | | RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator Abh | | 分子名称: | Putative transition state regulator abh | | 著者 | Sullivan, D.M, Bobay, B.G, Douglas, K.J, Thompson, R.J, Rance, M, Strauch, M.A, Cavanagh, J. | | 登録日 | 2008-03-08 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
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2R5H
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4UZN
 | | The native structure of the family 46 carbohydrate-binding module (CBM46) of endo-beta-1,4-glucanase B (Cel5B) from Bacillus halodurans | | 分子名称: | ENDO-BETA-1,4-GLUCANASE (CELULASE B) | | 著者 | Venditto, I, Santos, H, Ferreira, L.M.A, Sakka, K, Fontes, C.M.G.A, Najmudin, S. | | 登録日 | 2014-09-05 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Family 46 Carbohydrate-Binding Modules Contribute to the Enzymatic Hydrolysis of Xyloglucan and Beta-1,3-1,4-Glucans Through Distinct Mechanisms.
J.Biol.Chem., 290, 2015
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1NLI
 | | Complex of [E160A-E189A] trichosanthin and adenine | | 分子名称: | ADENINE, Ribosome-inactivating protein alpha-trichosanthin | | 著者 | Shaw, P.C, Wong, K.B, Chan, D.S.B, Williams, R.L. | | 登録日 | 2003-01-07 | | 公開日 | 2003-01-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural basis for the interaction of [E160A-E189A]-trichosanthin with adenine.
Toxicon, 41, 2003
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4UU9
 | | Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody | | 分子名称: | COMPLEMENT C5, MEDI7814, SULFATE ION | | 著者 | Colley, C, Sridharan, S, Dobson, C, Popovic, B, Debreczeni, J.E, Hargreaves, D, Edwards, B, Brennan, J, England, L, Fung, S, An Eghobamien, L, Sivars, U, Woods, R, Flavell, L, Renshaw, G.J, Wickson, K, Wilkinson, T, Davies, R, Bonnell, J, Warrener, P, Howes, R, Vaughan, T. | | 登録日 | 2014-07-25 | | 公開日 | 2015-08-12 | | 最終更新日 | 2019-02-27 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
MAbs, 10, 2018
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2R5J
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2R8F
 | | Crystal structure of H225A NSP2 and ATP-gS complex | | 分子名称: | Non-structural RNA-binding protein 35, PHOSPHATE ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Kumar, M, Prasad, B.V.V. | | 登録日 | 2007-09-10 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
J.Virol., 81, 2007
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2RBM
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4W1V
 | | Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a thiazole inhibitor | | 分子名称: | 1,2-ETHANEDIOL, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, CHLORIDE ION, ... | | 著者 | Finzel, B.C, Dai, R. | | 登録日 | 2014-08-13 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis.
Chem.Biol., 22, 2015
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