PDB: 7816 件ウェブページステータス検索Chemie searchBIRD

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3EI3	Structure of the hsDDB1-drDDB2 complex 分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2, TETRAETHYLENE GLYCOL 著者 Scrima, A, Thoma, N.H. 登録日 2008-09-15 公開日 2009-01-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
3H8N	Crystal Structure Analysis of KIR2DS4 分子名称: Killer cell immunoglobulin-like receptor 2DS4 著者 Graef, T, Bushnell, D.A, Parham, P. 登録日 2009-04-29 公開日 2009-10-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C. J.Exp.Med., 206, 2009
3H8M	SAM domain of human ephrin type-a receptor 7 (EPHA7) 分子名称: Ephrin type-A receptor 7 著者 Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2009-04-29 公開日 2009-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 SAM Domain of Human Ephrin Type-A Receptor 7 (Epha7) To be Published
3HCB	Crystal Structure of hPNMT in Complex With Noradrenochrome and AdoHcy 分子名称: (3S)-3-hydroxy-2,3-dihydro-1H-indole-5,6-dione, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L, Gee, C.L. 登録日 2009-05-06 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. Biochem.J., 422, 2009
3HC8	Investigation of Aminopyridiopyrazinones as PDE5 Inhibitors: Evaluation of Modifications to the Central Ring System. 分子名称: 6-(6-methoxypyridin-3-yl)-2-[(2-morpholin-4-ylethyl)amino]-4-(2-propoxyethyl)pyrido[2,3-b]pyrazin-3(4H)-one, MAGNESIUM ION, ZINC ION, ... 著者 Hughes, R.O, Stallings, W.C, Cubbage, J.W, Williams, J.M. 登録日 2009-05-05 公開日 2009-07-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system. Bioorg.Med.Chem.Lett., 19, 2009
3HFP	Crystal structure of teh complex between CA II and the activator MAI 分子名称: 1-[2-(1H-imidazol-4-yl)ethyl]-2,4,6-trimethylpyridinium, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Temperini, C, Supuran, C.T. 登録日 2009-05-12 公開日 2010-05-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 Crystal structure of teh complex between CA II and the activator MAI To be Published
3HIZ	Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Amzel, L.M, Vogelstein, B, Gabelli, S.B, Mandelker, D. 登録日 2009-05-20 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Proc.Natl.Acad.Sci.USA, 106, 2009
3HGZ	Crystal structure of human insulin-degrading enzyme in complex with amylin 分子名称: Insulin-degrading enzyme, Islet amyloid polypeptide, ZINC ION 著者 Guo, Q, Bian, Y, Tang, W.J. 登録日 2009-05-14 公開日 2009-12-08 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme. J.Mol.Biol., 395, 2010
3HDZ	Identification, Synthesis, and SAR of Amino Substituted Pyrido[3,2b]pryaziones as Potent and Selective PDE5 Inhibitors 分子名称: 5-amino-1-butyl-7-phenyl-1,6-naphthyridin-4(1H)-one, MAGNESIUM ION, ZINC ION, ... 著者 Cubbage, J.W, Brown, D.G, Jacobsen, E.J, Walker, J.K, Hughes, R.O. 登録日 2009-05-07 公開日 2009-07-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3HFV	Crystal structure of human mitochondrial phenylalanyl-tRNA synthetase complexed with m-tyrosine 分子名称: META-TYROSINE, Phenylalanyl-tRNA synthetase, mitochondrial 著者 Klipcan, L, Moor, N, Kessler, N, Safro, M.G. 登録日 2009-05-12 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine Proc.Natl.Acad.Sci.USA, 106, 2009
3HF4	Crystal structure of rat methemoglobin in R2 state 分子名称: Hemoglobin subunit alpha-1/2, Hemoglobin subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE 著者 Neelagandan, K, Sathya Moorthy, P, Balasubramanian, M, Ponnuswamy, M.N. 登録日 2009-05-11 公開日 2010-05-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Quaternary structural variability in rat hemoglobin To be Published
3HHM	Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin 分子名称: (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... 著者 Amzel, L.M, Vogelstein, B, Gabelli, S.B, Mandelker, D. 登録日 2009-05-15 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane. Proc.Natl.Acad.Sci.USA, 106, 2009
3HI6	Crystal structure of intermediate affinity I domain of integrin LFA-1 with the Fab fragment of its antibody AL-57 分子名称: Heavy chain of Fab fragment of AL-57 against alpha L I domain, Integrin alpha-L, MANGANESE (II) ION, ... 著者 Zhang, H, Wang, J. 登録日 2009-05-19 公開日 2009-09-22 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1. Proc.Natl.Acad.Sci.USA, 106, 2009
3HJM	Crystal structure of human Glutathione Transferase Pi Y108V mutant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... 著者 Parker, L.J. 登録日 2009-05-22 公開日 2009-09-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci., 18, 2009
3HFC	A trimeric form of the Kv7.1 A domain Tail, L602M/L606M mutant Semet 分子名称: Potassium voltage-gated channel subfamily KQT member 1 著者 Xu, Q, Minor, D.L. 登録日 2009-05-11 公開日 2009-09-01 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of a trimeric form of the K(V)7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif. Protein Sci., 18, 2009
3HFG	Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an Sulfonyl-piperazine Inhibitor 分子名称: (2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(1H-1,2,4-triazol-1-yl)phenyl]sulfonyl}piperazine, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Bard, J, Svenson, K. 登録日 2009-05-11 公開日 2009-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J.Med.Chem., 52, 2009

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