PDB: 7816 件ウェブページステータス検索Chemie searchBIRD

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3DWJ	Heme-proximal W188H mutant of inducible nitric oxide synthase 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, AMMONIUM ION, Nitric oxide synthase, ... 著者 Tejero, J, Biswas, A, Wang, Z.-Q, Haque, M.M, Hemann, C, Zweier, J.L, Page, R.C, Misra, S, Stuehr, D.J. 登録日 2008-07-22 公開日 2008-09-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Stabilization and Characterization of a Heme-Oxy Reaction Intermediate in Inducible Nitric-oxide Synthase J.Biol.Chem., 283, 2008
3GOU	Crystal structure of dog (Canis familiaris) hemoglobin 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Sundaresan, S.S, Ramesh, P, Thenmozhi, M, Ponnuswamy, M.N. 登録日 2009-03-20 公開日 2009-04-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of dog (Canis familiaris) hemoglobin To be Published
3GSQ	Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5S peptide variant 分子名称: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5S (NLVPSVATV), ... 著者 Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. 登録日 2009-03-27 公開日 2009-08-04 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
3GTG	Backtracked RNA polymerase II complex with 12mer RNA 分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.78 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
3GQR	Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.4 angstrom resolution 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta-A/B, PROTOPORPHYRIN IX CONTAINING FE 著者 Balasubramanian, M, Sathya Moorthy, P, Neelagandan, K, Ponnuswamy, M.N. 登録日 2009-03-24 公開日 2010-03-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.4 angstrom resolution To be Published
3GS7	Human transthyretin (TTR) complexed with (E)-3-(2-methoxybenzylideneaminooxy)propanoic acid (inhibitor 13) 分子名称: 3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid, Transthyretin 著者 Mohamedmohaideen, N.N, Palaninathan, S.K, Orlandini, E, Sacchettini, J.C. 登録日 2009-03-26 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis. Plos One, 4, 2009
3GV4	Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG 分子名称: CALCIUM ION, Histone deacetylase 6, ZINC ION, ... 著者 Dong, A, Ravichandran, M, Loppnau, P, Li, Y, MacKenzie, F, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Dhe-Paganon, S, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) 登録日 2009-03-30 公開日 2009-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG To be Published
3GZ0	Apo-human carbonic anhydrase II revisited: Implications of the loss of a metal in protein structure, stability and solvent network 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Avvaru, B.S, McKenna, R. 登録日 2009-04-06 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Apo-Human Carbonic Anhydrase II Revisited: Implications of the Loss of a Metal in Protein Structure, Stability, and Solvent Network . Biochemistry, 48, 2009
3H44	Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha 分子名称: 1,4-DIETHYLENE DIOXIDE, C-C motif chemokine 3, Insulin-degrading enzyme, ... 著者 Ren, M, Guo, Q, Tang, W.J. 登録日 2009-04-17 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Macrophage Inflammatory Protein-1 Is A Novel High Affinity Substrate For Human Insulin Degrading Enzyme To be Published
3HAJ	Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice) 分子名称: CALCIUM ION, human PACSIN2 F-BAR 著者 Wang, Q, Navarro, M.V.A.S, Peng, G, Rajashankar, K.R, Sondermann, H. 登録日 2009-05-01 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin. Proc.Natl.Acad.Sci.USA, 106, 2009
3HCA	Crystal Structure of E185Q hPNMT in Complex With Octopamine and AdoHcy 分子名称: 1,2-ETHANEDIOL, 4-(2R-AMINO-1-HYDROXYETHYL)PHENOL, Phenylethanolamine N-methyltransferase, ... 著者 Drinkwater, N, Martin, J.L. 登録日 2009-05-06 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. Biochem.J., 422, 2009
3H6A	Structure of the Calx-beta domain of integrin beta4 crystallized in the presence of calcium 分子名称: Integrin beta-4 著者 Alonso-Garcia, N, Ingles-Prieto, A, de Pereda, J.M. 登録日 2009-04-23 公開日 2009-06-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.608 Å) 主引用文献 Structure of the Calx-beta domain of the integrin beta4 subunit: insights into function and cation-independent stability Acta Crystallogr.,Sect.D, 65, 2009
3H6K	Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an Ortho-chlro-sulfonyl-piperazine Inhibitor 分子名称: 3-chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)benzamide, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Bard, J, Svenson, K. 登録日 2009-04-23 公開日 2009-12-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.187 Å) 主引用文献 Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J.Med.Chem., 52, 2009
3H7W	Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains with the artificial ligand THS017 分子名称: 2-nitro-N-(thiophen-3-ylmethyl)-4-(trifluoromethyl)aniline, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 著者 Key, J.M, Scheuermann, T.H, Anderson, P.C, Daggett, V, Gardner, K.H. 登録日 2009-04-28 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B J.Am.Chem.Soc., 131, 2009
3H82	Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains with the artificial ligand THS020 分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(furan-2-ylmethyl)-2-nitro-4-(trifluoromethyl)aniline 著者 Key, J.M, Scheuermann, T.H, Anderson, P.C, Daggett, V, Gardner, K.H. 登録日 2009-04-28 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B J.Am.Chem.Soc., 131, 2009
3EU0	Crystal structure of the S-nitrosylated Cys215 of PTP1B 分子名称: Tyrosine-protein phosphatase non-receptor type 1 著者 Chu, H.M, Wang, A.H.J, Chen, Y.Y, Pan, K.T, Wang, D.L, Khoo, K.H, Meng, T.C. 登録日 2008-10-09 公開日 2008-11-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Cysteine S-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation J.Biol.Chem., 283, 2008
3E50	Crystal structure of human insulin degrading enzyme in complex with transforming growth factor-alpha 分子名称: Insulin-degrading enzyme, Protransforming growth factor alpha, ZINC ION 著者 Guo, Q, Manolopoulou, M, Tang, W.-J. 登録日 2008-08-12 公開日 2009-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme. J.Mol.Biol., 395, 2010
3EB1	Crystal structure PTP1B complex with small molecule inhibitor LZP-25 分子名称: 4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid, Tyrosine-protein phosphatase non-receptor type 1 著者 Liu, S, Zheng, L.-F, Wu, L, Yu, X, Xue, T, Gunawan, A.M, Long, Y.-Q, Zhang, Z.-Y. 登録日 2008-08-26 公開日 2009-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors. J.Am.Chem.Soc., 130, 2008
3EAH	Structure of inhibited human eNOS oxygenase domain 分子名称: (3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... 著者 Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D. 登録日 2008-08-25 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
3EFI	Carbonic anhydrase activators: Kinetic and X-ray crystallographic study for the interaction of d- and l-tryptophan with the mammalian isoforms I-XIV 分子名称: Carbonic anhydrase 2, MERCURIBENZOIC ACID, TRYPTOPHAN, ... 著者 Temperini, C, Innocenti, A, Scozzafava, A, Supuran, C.T. 登録日 2008-09-09 公開日 2008-09-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV Bioorg.Med.Chem., 16, 2008
3EQT	Crystal structure of human LGP2 C-terminal domain in complex with dsRNA 分子名称: 5'-R(*GP*CP*GP*CP*GP*CP*GP*C)-3', ATP-dependent RNA helicase DHX58, ZINC ION 著者 Li, P, Li, X. 登録日 2008-10-01 公開日 2009-03-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA J.Biol.Chem., 284, 2009
3ET0	Structure of PPARgamma with 3-(5-Methoxy-1H-indol-3-yl)-propionic acid 分子名称: 3-(5-methoxy-1H-indol-3-yl)propanoic acid, Peroxisome proliferator-activated receptor gamma, alpha-D-glucopyranose 著者 Zhang, K.Y.J, Wang, W. 登録日 2008-10-06 公開日 2009-02-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Proc.Natl.Acad.Sci.USA, 106, 2009
3EOA	Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I 分子名称: Efalizumab Fab fragment, heavy chain, light chain, ... 著者 Li, S, Ding, J. 登録日 2008-09-26 公開日 2009-04-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc.Natl.Acad.Sci.USA, 106, 2009
3ET1	Structure of PPARalpha with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid 分子名称: 3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid, Peroxisome proliferator-activated receptor alpha, Steroid receptor coactivator 1 著者 Zhang, K.Y.J, Wang, W. 登録日 2008-10-06 公開日 2009-02-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent Proc.Natl.Acad.Sci.USA, 106, 2009
3E3B	Crystal structure of catalytic subunit of human protein kinase CK2alpha prime with a potent indazole-derivative inhibitor 分子名称: Casein kinase II subunit alpha', [1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid 著者 Kinoshita, T, Nakaniwa, T, Tada, T. 登録日 2008-08-07 公開日 2009-03-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of human protein kinase CK2alpha2 with a potent indazole-derivative inhibitor Acta Crystallogr.,Sect.F, 65, 2009

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