PDB: 7816 件ウェブページステータス検索Chemie searchBIRD

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3CAL	Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 分子名称: Fibronectin, peptide from Fibronectin-binding protein A 著者 Bingham, R.J. 登録日 2008-02-20 公開日 2008-08-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains Proc.Natl.Acad.Sci.Usa, 105, 2008
3CD0	Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors 分子名称: (3R,5R)-7-{2-[(4-fluorobenzyl)carbamoyl]-4-(4-fluorophenyl)-1-(1-methylethyl)-1H-imidazol-5-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase 著者 Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. 登録日 2008-02-26 公開日 2008-06-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
3CD7	Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors 分子名称: (3R,5R)-7-[5-(ANILINOCARBONYL)-3,4-BIS(4-FLUOROPHENYL)-1-ISOPROPYL-1H-PYRROL-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase 著者 Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. 登録日 2008-02-26 公開日 2008-06-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
3CDB	Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors 分子名称: (3R,5R)-7-{3-[(4-carbamoylphenyl)sulfamoyl]-4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-pyrrol-1-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase 著者 Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. 登録日 2008-02-26 公開日 2008-06-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
3CAD	Crystal structure of Natural Killer Cell Receptor, Ly49G 分子名称: Lectin-related NK cell receptor LY49G1 著者 Cho, S. 登録日 2008-02-19 公開日 2008-04-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell Receptors. J.Biol.Chem., 283, 2008
2JK7	XIAP BIR3 bound to a Smac Mimetic 分子名称: (3S,6S,7Z,10AS)-N-(DIPHENYLMETHYL)-6-{[(2S)-2-(METHYLIDENEAMINO)BUTANOYL]AMINO}-5-OXO-1,2,3,5,6,9,10,10A-OCTAHYDROPYRROLO[1,2-A]AZOCINE-3-CARBOXAMIDE, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, ZINC ION 著者 Saito, N.G, Meagher, J.L, Stuckey, J.A. 登録日 2008-08-21 公開日 2008-11-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (Xiap). J.Med.Chem., 51, 2008
3CBK	chagasin-cathepsin B 分子名称: Cathepsin B, Chagasin 著者 Redzynia, I, Bujacz, G.D, Abrahamson, M, Ljunggren, A, Jaskolski, M, Mort, J.S. 登録日 2008-02-22 公開日 2008-05-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. J.Biol.Chem., 283, 2008
2K2F	Solution structure of Ca2+-S100A1-RyRP12 分子名称: CALCIUM ION, Protein S100-A1, Ryanodine receptor 1 peptide 著者 Wright, N.T, Varney, K.M, Weber, D.J. 登録日 2008-04-01 公開日 2008-07-29 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor. J.Biol.Chem., 283, 2008
2JT0	Solution structure of F104W cardiac troponin C 分子名称: Troponin C, slow skeletal and cardiac muscles 著者 Wang, X, Mercier, P, Letourneau, P.-J, Sykes, B.D. 登録日 2007-07-17 公開日 2008-05-27 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies. Protein Sci., 14, 2005
3CDA	Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors 分子名称: (3R,5R)-7-{3-(4-fluorophenyl)-1-(1-methylethyl)-4-phenyl-5-[(4-sulfamoylphenyl)carbamoyl]-1H-pyrrol-2-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase 著者 Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. 登録日 2008-02-26 公開日 2008-06-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
3CDS	Crystal structure of the complex between PPAR-gamma and the agonist LT248 (clofibric acid analogue) 分子名称: (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Pochetti, G, Montanari, R, Mazza, F. 登録日 2008-02-27 公開日 2008-12-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structure of the Peroxisome Proliferator-Activated Receptor gamma (PPARgamma) Ligand Binding Domain Complexed with a Novel Partial Agonist: A New Region of the Hydrophobic Pocket Could Be Exploited for Drug Design J.Med.Chem., 51, 2008
3DGZ	Crystal Structure of Mouse Mitochondrial Thioredoxin Reductase, C-terminal 3-residue truncation 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase 2, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE 著者 Eckenroth, B.E, Hondal, R.J, Everse, S.J. 登録日 2008-06-16 公開日 2009-06-16 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Mouse Mitochondrial Thioredoxin Reductase, C-terminal 3-residue truncation To be Published
3DE7	Proteinase K by Classical hanging drop method after the fourth step of high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-06-08 公開日 2009-06-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009
2Z17	Crystal structure of PDZ domain from human Pleckstrin homology, Sec7 分子名称: Pleckstrin homology Sec7 and coiled-coil domains-binding protein 著者 Kishishita, S, Nishino, A, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-05-08 公開日 2008-05-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of PDZ domain from human Pleckstrin homology, Sec7 To be Published
3DNZ	Thermolysin by LB nanotemplate method before high X-Ray dose on ESRF ID14-2 beamline 分子名称: CALCIUM ION, LYSINE, Thermolysin, ... 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-07-03 公開日 2009-07-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Radiation damage in protein structural characterization by Synchrotron Radiation: State of the art and Nanotechnology-based perspective To be Published
3DE4	Proteinase K by Classical hanging drop method after the first step of high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-06-08 公開日 2009-06-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009
3A60	Crystal structure of unphosphorylated p70S6K1 (Form I) 分子名称: Ribosomal protein S6 kinase beta-1, STAUROSPORINE 著者 Sunami, T, Byrne, N, Diehl, R.E, Funabashi, K, Hall, D.L, Ikuta, M, Patel, S.B, Shipman, J.M, Smith, R.F, Takahashi, I, Zugay-Murphy, J, Iwasawa, Y, Lumb, K.J, Munshi, S.K, Sharma, S. 登録日 2009-08-17 公開日 2009-10-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation. J.Biol.Chem., 285, 2010
3A7X	Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking 45seconds) 分子名称: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ... 著者 Yamane, J, Yao, M, Tanaka, I. 登録日 2009-10-05 公開日 2010-09-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 In-Crystal Chemical Ligation for Drug Discovery To be Published
3A86	Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking 30 seconds) 分子名称: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ... 著者 Yamane, J, Yao, M, Tanaka, I. 登録日 2009-10-05 公開日 2010-09-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 In-Crystal Chemical Ligation for Drug Discovery To be Published
3A81	Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 8 hours) 分子名称: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... 著者 Yamane, J, Yao, M, Tanaka, I. 登録日 2009-10-05 公開日 2010-09-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 In-Crystal Chemical Ligation for Drug Discovery To be Published
3DUY	Crystal structure of human beta-secretase in complex with NVP-AFJ144 分子名称: (2R,4S,5S)-N-butyl-4-hydroxy-2,7-dimethyl-5-{[N-(4-methylpentanoyl)-L-methionyl]amino}octanamide, Beta-secretase 1 著者 Rondeau, J.-M. 登録日 2008-07-18 公開日 2009-02-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3DVS	Proteinase K by LB nanotmplate method after the second step of high dose on ESRF ID14-2 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-07-20 公開日 2009-07-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Radiation damage in protein structural characterization by Synchrotron Radiation: State of the art and Nanotechnology-based perspective To be Published
2L40	Mouse prion protein (121-231) containing the substitution Y169A 分子名称: Major prion protein 著者 Christen, B, Damberger, F.F, Perez, D.R, Hornemann, S, Wuthrich, K. 登録日 2010-09-28 公開日 2011-08-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Cellular prion protein conformation and function. Proc.Natl.Acad.Sci.USA, 108, 2011
3DWD	Crystal structure of the ArfGAP domain of human ARFGAP1 分子名称: ADP-ribosylation factor GTPase-activating protein 1, UNKNOWN ATOM OR ION, ZINC ION 著者 Nedyalkova, L, Tong, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2008-07-22 公開日 2008-08-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the ArfGAP domain of human ARFGAP1 To be Published
3DE3	Proteinase K by Classical hanging drop method before high X-Ray dose on ESRF ID23-1 beamline 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Nicolini, C. 登録日 2008-06-08 公開日 2009-06-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Radiation stability of proteinase K crystals grown by LB nanotemplate method J.Struct.Biol., 168, 2009

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