PDB: 7816 件ウェブページステータス検索Chemie searchBIRD

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2Z5Y	Crystal Structure of Human Monoamine Oxidase A (G110A) with Harmine 分子名称: 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, Amine oxidase [flavin-containing] A, DECYL(DIMETHYL)PHOSPHINE OXIDE, ... 著者 Son, S.Y, Ma, J, Yoshimura, M, Tsukihara, T. 登録日 2007-07-20 公開日 2008-04-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structure of human monoamine oxidase A at 2.2-A resolution: The control of opening the entry for substrates/inhibitors Proc.Natl.Acad.Sci.Usa, 105, 2008
2JCR	The hyaluronan binding domain of murine CD44 in a Type B complex with an HA 8-mer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD44 ANTIGEN, GLYCEROL 著者 Banerji, S, Wright, A.J, Noble, M.E.M, Mahoney, D.J, Campbell, I.D, Day, A.J, Jackson, D.G. 登録日 2007-01-03 公開日 2007-01-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of the Cd44-Hyaluronan Complex Provide Insight Into a Fundamental Carbohydrate-Protein Interaction. Nat.Struct.Mol.Biol., 14, 2008
2JHL	Structure of globular heads of M-ficolin complexed with sialic acid 分子名称: CALCIUM ION, FICOLIN-1, N-acetyl-beta-neuraminic acid 著者 Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. 登録日 2007-02-22 公開日 2007-10-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
2ZF0	Exploring Thrombin S1 Pocket 分子名称: D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide, Hirudin variant-1, SODIUM ION, ... 著者 Baum, B, Heine, A, Klebe, G. 登録日 2007-12-18 公開日 2008-11-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Exploring Thrombin S1 pocket To be Published
2ZGC	Crystal Structure of Active Human Granzyme M 分子名称: Granzyme M, SULFATE ION 著者 Wu, L.F, Wang, L, Hua, G.Q, Liu, K, Zhai, Y.J, Sun, F, Fan, Z.S. 登録日 2008-01-21 公開日 2009-01-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M J.Immunol., 183, 2009
2ZHD	Exploring trypsin S3 pocket 分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ... 著者 Brandt, T, Baum, B, Heine, A, Klebe, G. 登録日 2008-02-04 公開日 2009-02-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties J.Mol.Biol., 405, 2011
2ZFS	Exploring trypsin S3 pocket 分子名称: CALCIUM ION, Cationic trypsin, DIMETHYL SULFOXIDE, ... 著者 Brandt, T, Baum, B, Heine, A, Klebe, G. 登録日 2008-01-10 公開日 2009-01-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties J.Mol.Biol., 405, 2011
2JUL	NMR Structure of DREAM 分子名称: CALCIUM ION, Calsenilin 著者 Ames, J. 登録日 2007-08-30 公開日 2008-04-22 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR structure of DREAM: Implications for Ca(2+)-dependent DNA binding and protein dimerization. Biochemistry, 47, 2008
2JY7	NMR structure of the ubiquitin associated (UBA) domain of p62 (SQSTM1). RDC refined 分子名称: Ubiquitin-binding protein p62 著者 Long, J.E, Layfield, R, Searle, M.S. 登録日 2007-12-07 公開日 2007-12-18 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Ubiquitin Recognition by the Ubiquitin-associated Domain of p62 Involves a Novel Conformational Switch J.Biol.Chem., 283, 2008
2K07	Solution NMR structure of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1). Northeast Structural Genomics Consortium target HR41 分子名称: Ufm1-conjugating enzyme 1 著者 Liu, G, Eletsky, A, Atreya, H.S, Aramini, J.M, Xiao, R, Acton, T, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) 登録日 2008-01-25 公開日 2008-02-19 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway. J.STRUCT.FUNCT.GENOM., 10, 2009
2JW5	Polymerase Lambda BRCT domain 分子名称: DNA polymerase lambda 著者 Mueller, G.A, Moon, A.F, DeRose, E.F, Pedersen, L.C, London, R.E. 登録日 2007-10-05 公開日 2007-10-23 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Polymerase Lambda BRCT domain To be Published
2ZIL	Crystal Structure of Human Lysozyme from Urine 分子名称: Lysozyme C, SODIUM ION 著者 Tamada, T, Kuroki, R, Koshiba, T. 登録日 2008-02-18 公開日 2009-01-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Preparation and characterization of methyonyl-lysine attached human lysozyme expressed in Escherichia coli and its effective conversion to the authentic-like protein To be Published
2ZJI	Crystal structure of the human BACE1 catalytic domain in complex with N-[1-(2,6-dimethoxy-benzyl)-piperidin-4-yl]-4-mercapto-butyramide 分子名称: Beta-secretase 1, N-[1-(2,6-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide 著者 Randal, M, Lam, M.B, Romanowski, M.J. 登録日 2008-03-07 公開日 2009-01-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment-based discovery of novel BACE1 inhibitors using Tethering technology To be Published
2ZLW	Horse methemoglobin high salt, pH 7.0 (75% relative humidity) 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Kaushal, P.S, Sankaranarayanan, R, Vijayan, M. 登録日 2008-04-10 公開日 2008-06-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Water-mediated variability in the structure of relaxed-state haemoglobin Acta Crystallogr.,Sect.F, 64, 2008
2JYU	Human Granulin C, isomer 2 分子名称: Granulin-5 著者 Tolkatchev, D, Wang, P, Chen, Z, Xu, P, Ni, F. 登録日 2007-12-19 公開日 2008-04-22 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities. Protein Sci., 17, 2008
2ZNT	Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with a novel selective agonist, dysiherbaine 分子名称: (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid, BETA-MERCAPTOETHANOL, Glutamate receptor, ... 著者 Unno, M, Sasaki, M, Ikeda-Saito, M. 登録日 2008-05-01 公開日 2009-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors. J.Mol.Biol., 413, 2011
3GYL	Structure of Prostasin at 1.3 Angstroms resolution in complex with a Calcium Ion. 分子名称: CALCIUM ION, GLYCEROL, Prostasin 著者 Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. 登録日 2009-04-03 公開日 2009-04-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations. Protein Sci., 18, 2009
2ZQ1	Exploring trypsin S3 pocket 分子名称: (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... 著者 Brandt, T, Baum, B, Heine, A, Klebe, G. 登録日 2008-08-03 公開日 2009-08-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties J.Mol.Biol., 405, 2011
2K40	NMR structure of HESX-1 homeodomain double mutant R31L/E42L 分子名称: Homeobox expressed in ES cells 1 著者 Asensio, J, Torrado, M, Gonzalez, C, Bastida, A. 登録日 2008-05-26 公開日 2009-05-05 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The role of conserved salt-bridges on homeodomain stability To be Published
2ZPX	TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity; R1antTNF-T8 分子名称: Tumor necrosis factor 著者 Mukai, Y, Nakamura, T, Yamagata, Y, Tsutsumi, Y. 登録日 2008-07-29 公開日 2009-03-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists J.Biochem., 146, 2009
2K4A	FGF-1-C2A binary complex structure: a key component in the fibroblast growthfactor non-classical pathway 分子名称: Heparin-binding growth factor 1, Synaptotagmin-1 著者 Yu, C, Mohan, S.K. 登録日 2008-06-02 公開日 2009-06-09 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release To be Published
3GPW	Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand 分子名称: (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE, Proteasome component C1, Proteasome component C11, ... 著者 Groll, M, Macherla, V.R, Manam, R.R, Arthur, K.A.M, Potts, C.B. 登録日 2009-03-23 公開日 2009-09-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition J.Med.Chem., 52, 2009
3H42	Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody 分子名称: Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ... 著者 Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E. 登録日 2009-04-17 公開日 2009-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc.Natl.Acad.Sci.USA, 106, 2009
2K3G	NMR structure analysis of a BMP receptor 分子名称: Bone morphogenetic protein receptor type-1A 著者 Klages, J, Kotzsch, A, Mueller, T, Kessler, H. 登録日 2008-05-07 公開日 2008-12-16 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding. Biochemistry, 47, 2008
3HBU	PrtC methionine mutants: M226H DESY 分子名称: CALCIUM ION, CHLORIDE ION, Secreted protease C, ... 著者 Oberholzer, A.E, Bumann, M, Hege, T, Russo, S, Baumann, U. 登録日 2009-05-05 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site Biol.Chem., 390, 2009

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