PDB: 245663 件ウェブページステータス検索Chemie searchBIRD

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2ZMA	Crystal Structure of 6-Aminohexanoate-dimer Hydrolase S112A/G181D/H266N/D370Y Mutant with Substrate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-AMINOHEXANOIC ACID, 6-aminohexanoate-dimer hydrolase, ... 著者 Ohki, T, Shibata, N, Higuchi, Y, Takeo, M, Negoro, S. 登録日 2008-04-14 公開日 2009-04-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a beta-lactamase fold Febs J., 276, 2009
2OA2	Crystal structure of BH2720 (10175341) from Bacillus halodurans at 1.41 A resolution 分子名称: BH2720 protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-12-14 公開日 2007-01-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Crystal structure of BH2720 (10175341) from Bacillus halodurans at 1.41 A resolution To be published
2ZO5	Structure of the Thioalkalivibrio nitratireducens cytochrome c nitrite reductase in a complex with azide 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AZIDE ION, ... 著者 Polyakov, K.M, Boyko, K.M, Slutsky, A, Tikhonova, T.V, Antipov, A.N, Zvyagilskaya, R.A, Popov, A.N, Lamzin, V.S, Bourenkov, G.P, Popov, V.O. 登録日 2008-05-05 公開日 2009-05-05 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High-resolution structural analysis of a novel octaheme cytochrome c nitrite reductase from the haloalkaliphilic bacterium Thioalkalivibrio nitratireducens J.Mol.Biol., 389, 2009
4AWJ	pVHL:EloB:EloC complex, in complex with capped Hydroxyproline 分子名称: (4R)-1-acetyl-4-hydroxy-N-methyl-L-prolinamide, ACETATE ION, ACETIC ACID, ... 著者 Van Molle, I, Thomann, A, Buckley, D.L, So, E.C, Lang, S, Crews, C.M, Ciulli, A. 登録日 2012-06-04 公開日 2012-11-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface. Chem.Biol., 19, 2012
3RK6	Crystal structure of the middle domain of human Paip1 分子名称: Polyadenylate-binding protein-interacting protein 1 著者 Lei, J, Mesters, J.R, Hilgenfeld, R. 登録日 2011-04-17 公開日 2011-05-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the middle domain of human poly(A)-binding protein-interacting protein 1. Biochem.Biophys.Res.Commun., 408, 2011
2OJJ	Crystal structure of ERK2 in complex with (S)-N-(1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl)-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide 分子名称: (S)-N-(1-(3-CHLORO-4-FLUOROPHENYL)-2-HYDROXYETHYL)-4-(4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE, Mitogen-activated protein kinase 1, SULFATE ION 著者 Xie, X, Jacobs, M.D. 登録日 2007-01-12 公開日 2007-02-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors. J.Med.Chem., 50, 2007
2ASC	Scorpion toxin LQH-alpha-IT 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ... 著者 Kahn, R, Karbat, I, Gurevitz, M, Frolow, F. 登録日 2005-08-23 公開日 2006-09-05 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant To be Published
2JF4	Family 37 trehalase from Escherichia coli in complex with validoxylamine 分子名称: (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL, PERIPLASMIC TREHALASE 著者 Gibson, R.P, Gloster, T.M, Roberts, S, Warren, R.A.J, Storch De Gracia, I, Garcia, A, Chiara, J.L, Davies, G.J. 登録日 2007-01-25 公開日 2007-02-13 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors. Angew.Chem.Int.Ed.Engl., 46, 2007
3ZZK	Structure of an engineered aspartate aminotransferase 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, GLYCEROL, ... 著者 Fernandez, F.J, deVries, D, Pena-Soler, E, Coll, M, Christen, P, Gehring, H, Vega, M.C. 登録日 2011-09-01 公開日 2011-12-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold. Biocim.Biophys.Acta, 1824, 2011
3RN8	Crystal Structure of iGluR2 Ligand Binding Domain and Symmetrical Carboxyl Containing Potentiator 分子名称: 3,3'-benzene-1,4-diylbis(4-cyano-5-ethylthiophene-2-carboxylic acid), ACETATE ION, GLUTAMIC ACID, ... 著者 Timm, D.E. 登録日 2011-04-22 公開日 2011-05-25 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol.Pharmacol., 80, 2011
5E76	Crystal structure of Bacova_02651 with xylogluco-oligosaccharide 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... 著者 Koropatkin, N.M. 登録日 2015-10-11 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Dissection of Xyloglucan Recognition in a Prominent Human Gut Symbiont. Mbio, 7, 2016
5DLW	Crystal structure of Autotaxin (ENPP2) with tauroursodeoxycholic acid (TUDCA) and lysophosphatidic acid (LPA) 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 2-{[(3alpha,5beta,7alpha,8alpha,14beta,17alpha)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid, CALCIUM ION, ... 著者 Keune, W.J, Heidebrecht, T, Joosten, R.P, Perrakis, A. 登録日 2015-09-07 公開日 2016-04-13 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. Nat Commun, 7, 2016
2QQI	Crystal Structure of the b1b2 Domains from Human Neuropilin-1 分子名称: GLYCEROL, Neuropilin-1 著者 Appleton, B.A, Desmarais, W, Wiesmann, C. 登録日 2007-07-26 公開日 2007-11-20 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding Embo J., 26, 2007
1V0L	Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-isofagomine at pH 5.8 分子名称: ENDO-1,4-BETA-XYLANASE A, PIPERIDINE-3,4-DIOL, beta-D-xylopyranose 著者 Gloster, T.M, Williams, S.J, Roberts, S, Tarling, C.A, Wicki, J, Withers, S.G, Davies, G.J. 登録日 2004-03-31 公開日 2004-08-16 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Atomic Resolution Analyses of the Binding of Xylobiose-Derived Deoxynojirimycin and Isofagomine to Xylanase Xyn10A Chem.Commun.(Camb.), 16, 2004
1V2A	Glutathione S-transferase 1-6 from Anopheles dirus species B 分子名称: GLUTATHIONE SULFONIC ACID, glutathione transferase gst1-6 著者 Oakley, A.J. 登録日 2003-10-10 公開日 2003-10-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Identification, characterization and structure of a new Delta class glutathione transferase isoenzyme. Biochem.J., 388, 2005
2QKK	Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*G)-3', ... 著者 Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W. 登録日 2007-07-11 公開日 2007-11-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription Mol.Cell, 28, 2007
3BKQ	Structure of the P368G mutant of PMM/PGM in complex with its substrate 分子名称: 1-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase/phosphoglucomutase, ZINC ION 著者 Mehra-Chaudhary, R, Beamer, L.J. 登録日 2007-12-07 公開日 2008-09-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Backbone flexibility, conformational change, and catalysis in a phosphohexomutase from Pseudomonas aeruginosa. Biochemistry, 47, 2008
3RB6	Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 3-methylcytosine (m3c) lesion 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Rechkoblit, O, Patel, D.J. 登録日 2011-03-28 公開日 2011-06-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure, 19, 2011
6ETY	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor JHU3371 分子名称: (2~{S})-2-[[(2~{R})-4-methyl-1-oxidanyl-1-oxidanylidene-pentan-2-yl]carbamoyloxy]pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barinka, C, Novakova, Z, Motlova, L. 登録日 2017-10-27 公開日 2018-11-07 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors. Bioorg.Med.Chem., 27, 2019
3ITB	Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in complex with a substrate fragment 分子名称: D-alanyl-D-alanine carboxypeptidase DacC, Peptidoglycan substrate (AMV)A(FGA)K(DAL)(DAL), SULFATE ION, ... 著者 Chen, Y, Zhang, W, Shi, Q, Hesek, D, Lee, M, Mobashery, S, Shoichet, B.K. 登録日 2009-08-27 公開日 2009-10-20 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of penicillin-binding protein 6 from Escherichia coli. J.Am.Chem.Soc., 131, 2009
2EUF	X-ray structure of human CDK6-Vcyclin in complex with the inhibitor PD0332991 分子名称: 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, ACETATE ION, CALCIUM ION, ... 著者 Schulze-Gahmen, U, Lu, H. 登録日 2005-10-28 公開日 2006-07-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Toward understanding the structural basis of cyclin-dependent kinase 6 specific inhibition. J.Med.Chem., 49, 2006
2EWY	Crystal structure of human BACE2 in complex with a hydroxyethylenamine transition-state inhibitor 分子名称: Beta-secretase 2, N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHYLBENZYL)AMINO]PROPYL}DIBENZO[B,F]OXEPINE-10-CARBOXAMIDE 著者 Ostermann, N. 登録日 2005-11-07 公開日 2006-11-07 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of human BACE2 in complex with a hydroxyethylamine transition state inhibitor J.Mol.Biol., 355, 2006
2Z54	The Influence of I47A Mutation on Reduced Susceptibility to the Protease Inhibitor Lopinavir 分子名称: BETA-MERCAPTOETHANOL, HIV-1 Protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE 著者 Brynda, J, Klara, S, Kozisek, M, Lepsik, M, Machala, L, Konvalinka, J. 登録日 2007-06-28 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir. Protein Sci., 17, 2008
3RJ3	Complement components factor H CCP19-20 (S1191L mutant) and C3D in complex 分子名称: Complement C3d fragment, Complement Factor H-related protein 1, GLYCEROL 著者 Morgan, H.P, Hannan, J.P. 登録日 2011-04-15 公開日 2012-03-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural and functional characterization of the product of disease-related factor h gene conversion. Biochemistry, 51, 2012
2C2B	Crystallographic structure of Arabidopsis thaliana Threonine synthase complexed with pyridoxal phosphate and S-adenosylmethionine 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYRIDOXAL-5'-PHOSPHATE, S-ADENOSYLMETHIONINE, ... 著者 Mas-Droux, C, Biou, V, Dumas, R. 登録日 2005-09-27 公開日 2005-11-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Allosteric Threonine Synthase: Reorganization of the Pyridoxal Phosphate Site Upon Asymmetric Activation Through S-Adenosylmethionine Binding to a Novel Site. J.Biol.Chem., 281, 2006

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