PDB: 245663 件ウェブページステータス検索Chemie searchBIRD

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2Q5W	The X-ray Crystal Structure of Molybdopterin Synthase from Staphylococcus aureus 分子名称: GLYCEROL, Molybdopterin converting factor, subunit 1, ... 著者 Daniels, J.N, Schindelin, H. 登録日 2007-06-03 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency. Biochemistry, 47, 2008
3MJ5	Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation 分子名称: N-(1,3-benzodioxol-5-ylmethyl)-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Replicase polyprotein 1a, ZINC ION 著者 Mesecar, A.D, Ratia, K.M, Pegan, S.D. 登録日 2010-04-12 公開日 2010-06-30 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation J.Med.Chem., 53, 2010
2FL7	S. cerevisiae Sir3 BAH domain 分子名称: Regulatory protein SIR3 著者 Keck, J.L, Hou, Z, Daner, J.R, Fox, C.A. 登録日 2006-01-05 公開日 2006-05-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of the Sir3 protein bromo adjacent homology (BAH) domain from S. cerevisiae at 1.95 A resolution. Protein Sci., 15, 2006
1GKJ	Histidine Ammonia-Lyase (HAL) Mutant Y280F from Pseudomonas putida 分子名称: GLYCEROL, HISTIDINE AMMONIA-LYASE, SULFATE ION 著者 Baedeker, M, Schulz, G.E. 登録日 2001-08-15 公開日 2002-04-05 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of Two Histidine Ammonia-Lyase Modifications and Implications for the Catalytic Mechanism Eur.J.Biochem., 269, 2002
3AJ7	Crystal Structure of isomaltase from Saccharomyces cerevisiae 分子名称: CALCIUM ION, Oligo-1,6-glucosidase 著者 Yamamoto, K, Miyake, H, Kusunoki, M, Osaki, S. 登録日 2010-05-26 公開日 2010-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structures of isomaltase from Saccharomyces cerevisiae and in complex with its competitive inhibitor maltose Febs J., 277, 2010
4OPO	Crystal structure of P domain from norovirus strain Saga4 in complex with HBGA type Leb (tetraglycan) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, VP1, ... 著者 Singh, B.K, Hansman, G.S. 登録日 2014-02-06 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Human noroviruses' fondness for histo-blood group antigens. J.Virol., 89, 2015
2F2L	Crystal structure of tracheal cytotoxin (TCT) bound to the ectodomain complex of peptidoglycan recognition proteins LCa (PGRP-LCa) and LCx (PGRP-LCx) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetylamino-2-deoxy-alpha-L-idopyranose, CITRIC ACID, ... 著者 Chang, C.I, Deisenhofer, J. 登録日 2005-11-17 公開日 2006-04-04 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of tracheal cytotoxin in complex with a heterodimeric pattern-recognition receptor. Science, 311, 2006
2R1N	OpdA from Agrobacterium radiobacter with bound slow substrate diethyl 4-methoxyphenyl phosphate (20h)- 1.7 A 分子名称: COBALT (II) ION, DIETHYL 4-METHOXYPHENYL PHOSPHATE, FE (II) ION, ... 著者 Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. 登録日 2007-08-23 公開日 2008-02-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase J.Mol.Biol., 375, 2008
5PAQ	Crystal Structure of Factor VIIa in complex with 2-[(1-aminoisoquinolin-6-yl)amino]-2-(3-ethoxy-4-propan-2-yloxyphenyl)-1-(2-phenylpyrrolidin-1-yl)ethanone 分子名称: 2-[(1-aminoisoquinolin-6-yl)amino]-2-(3-ethoxy-4-propan-2-yloxyphenyl)-1-(2-phenylpyrrolidin-1-yl)ethanone, CALCIUM ION, CHLORIDE ION, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
2JEW	Crystal structure of ((2S)-5-amino-2-((1-n-propyl-1H-imidazol-4-yl) methyl)pentanoic acid) UK396,082 a TAFIa inhibitor, Bound to Activated Porcine Pancreatic carboxypeptidaseB 分子名称: (2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]PENTANOIC ACID, CARBOXYPEPTIDASE B, ZINC ION 著者 Brown, D.G, Moore, R.S. 登録日 2007-01-24 公開日 2007-11-20 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. J. Med. Chem., 50, 2007
4BAL	Thaumatin from Thaumatococcus daniellii structure in complex with the europium tris-hydroxymethyltriazoledipicolinate complex at 1.30 A resolution. 分子名称: 4-(4-(hydroxymethyl)-1h-1,2,3-triazol-1-yl)pyridine-2,6-dicarboxylic acid, EUROPIUM (III) ION, THAUMATIN-1 著者 Talon, R, Kahn, R, Gautier, A, Nauton, L, Girard, E. 登録日 2012-09-14 公開日 2012-11-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.298 Å) 主引用文献 Clicked Europium Dipicolinate Complexes for Protein X-Ray Structure Determination. Chem.Commun.(Camb.), 48, 2012
2F29	Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor 分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 著者 Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. 登録日 2005-11-15 公開日 2006-11-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.921 Å) 主引用文献 Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor To be Published
3I6M	3D Structure of Torpedo californica acetylcholinesterase complexed with N-piperidinopropyl-galanthamine 分子名称: (4aS,6R,8aS)-3-methoxy-11-(3-piperidin-1-ylpropyl)-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Lamba, D, Bartolucci, C. 登録日 2009-07-07 公開日 2010-01-12 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Probing Torpedo californica acetylcholinesterase catalytic gorge with two novel bis-functional galanthamine derivatives. J.Med.Chem., 53, 2010
1CL2	CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOETHOXYVINYLGLYCINE 分子名称: (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, CYSTATHIONINE BETA-LYASE 著者 Clausen, T, Huber, R, Messerschmidt, A. 登録日 1997-09-04 公開日 1998-09-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study. Biochemistry, 36, 1997
1JGI	Crystal Structure of the Active Site Mutant Glu328Gln of Amylosucrase from Neisseria polysaccharea in Complex with the Natural Substrate Sucrose 分子名称: amylosucrase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose 著者 Mirza, O, Skov, L.K, Gajhede, M. 登録日 2001-06-25 公開日 2001-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of amylosucrase from Neisseria polysaccharea in complex with D-glucose and the active site mutant Glu328Gln in complex with the natural substrate sucrose. Biochemistry, 40, 2001
7EVQ	Crystal structure of C-terminal half of lactoferrin obtained by limited proteolysis using pepsin at 2.6 A resolution 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, ... 著者 Viswanathan, V, Singh, J, Sharma, P, Sharma, S, Singh, T.P. 登録日 2021-05-21 公開日 2021-06-09 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of C-terminal half of lactoferrin obtained by limited proteolysis using pepsin at 2.6 A resolution To Be Published
1CV2	Hydrolytic haloalkane dehalogenase linb from sphingomonas paucimobilis UT26 AT 1.6 A resolution 分子名称: HALOALKANE DEHALOGENASE 著者 Marek, J, Vevodova, J, Damborsky, J, Smatanova, I, Svensson, L.A, Newman, J, Nagata, Y, Takagi, M. 登録日 1999-08-22 公開日 2000-09-11 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26. Biochemistry, 39, 2000
2G5T	Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ag 分子名称: 3-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-4-CHLOROBENZOIC ACID, Dipeptidyl peptidase 4 著者 Longenecker, K.L, Fry, E.H, Lake, M.R, Solomon, L.R, Pei, Z, Li, X. 登録日 2006-02-23 公開日 2006-07-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors. J.Med.Chem., 49, 2006
2GA1	Crystal structure of a duf433 member protein (ava_0674) from anabaena variabilis atcc 29413 at 2.00 A resolution 分子名称: GLYCEROL, Protein of unknown function DUF433 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-03-07 公開日 2006-03-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of (YP_321193.1) from Anabaena variabilis ATCC 29413 at 2.00 A resolution To be published
2GEV	Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-II (LT) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Pantothenate kinase, ... 著者 Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M. 登録日 2006-03-20 公開日 2006-06-06 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK. Acta Crystallogr.,Sect.D, 62, 2006
2GF6	CRYSTAL STRUCTURE OF A PUTATIVE THIOESTERASE (SSO2295) FROM SULFOLOBUS SOLFATARICUS AT 1.91 A RESOLUTION 分子名称: CALCIUM ION, COENZYME A, Conserved hypothetical protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-03-21 公開日 2006-04-18 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Crystal structure of Conserved hypothetical protein (13815598) from Sulfolobus solfataricus at 1.91 A resolution To be published
7FAZ	Crystal structure of the SARS-CoV-2 main protease in complex with Y180 分子名称: (2~{R})-~{N}-dibenzofuran-3-yl-~{N}-[(1~{R})-2-[[(1~{S})-1-(4-fluorophenyl)ethyl]amino]-2-oxidanylidene-1-pyridin-3-yl-ethyl]-2-oxidanyl-propanamide, 3C-like proteinase, SODIUM ION 著者 Zeng, R, Quan, B.X, Liu, X.L, Lei, J. 登録日 2021-07-08 公開日 2021-07-21 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An orally available M pro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron. Nat Microbiol, 7, 2022
2C2M	Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors. 分子名称: AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-14-[4-(BENZYLOXY)-4-OXOBUTANOYL]-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14 -PENTAAZAHEXADECAN-16-OIC ACID, ... 著者 Ganesan, R, Jelakovic, S, Ekici, O.D, Li, Z.Z, James, K.E, Asgian, J.L, Campbell, A, Mikolajczyk, J, Salvesen, G.S, Gruetter, M.G, Powers, J.C. 登録日 2005-09-29 公開日 2006-09-20 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10. J.Med.Chem., 49, 2006
2C2K	Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors. 分子名称: AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-14-(4-ETHOXY-4-OXOBUTANOYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN -16-OIC ACID, ... 著者 Ganesan, R, Jelakovic, S, Ekici, O.D, Li, Z.Z, James, K.E, Asgian, J.L, Campbell, A.J, Mikolajczyk, J, Salvesen, G.S, Gruetter, M.G, Powers, J.C. 登録日 2005-09-29 公開日 2006-09-20 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10. J.Med.Chem., 49, 2006
3W09	Influenza virus neuraminidase subtype N9 (TERN) complexed with 2,3-dif guanidino-neu5ac2en inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-3-fluoro-D-glycero-D-galacto-non-2-enonic acid, ... 著者 Streltsov, V.A. 登録日 2012-10-25 公開日 2013-05-01 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activity Science, 340, 2013

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