PDB: 7816 件ウェブページステータス検索Chemie searchBIRD

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2ZW3	Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution 分子名称: Gap junction beta-2 protein 著者 Maeda, S, Nakagawa, S, Suga, M, Yamashita, E, Oshima, A, Fujiyoshi, Y, Tsukihara, T. 登録日 2008-12-01 公開日 2009-04-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure of the connexin 26 gap junction channel at 3.5 A resolution Nature, 458, 2009
2ZG1	Crystal Structure of Two N-terminal Domains of Siglec-5 in Complex with 6'-Sialyllactose 分子名称: N-acetyl-alpha-neuraminic acid, Sialic acid-binding Ig-like lectin 5 著者 Zhuravleva, M.A, Sun, P.D. 登録日 2008-01-17 公開日 2008-02-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural implications of Siglec-5-mediated sialoglycan recognition J.Mol.Biol., 375, 2008
2IVS	Crystal structure of non-phosphorylated RET tyrosine kinase domain 分子名称: 2',3'- cyclic AMP, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET 著者 Knowles, P.P, Murray-Rust, J, McDonald, N.Q. 登録日 2006-06-16 公開日 2006-08-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and Chemical Inhibition of the Ret Tyrosine Kinase Domain. J.Biol.Chem., 281, 2006
2Z7G	Crystal structure of adenosine deaminase ligated with EHNA 分子名称: (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol, Adenosine deaminase, ZINC ION 著者 Kinoshita, T. 登録日 2007-08-20 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Conformational change of adenosine deaminase during ligand-exchange in a crystal Biochem.Biophys.Res.Commun., 373, 2008
2ZGV	Crystal Structure of human phosphoglycerate kinase bound to D-ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Phosphoglycerate kinase 1 著者 Arold, S.T, Gondeau, C, Lionne, C, Chaloin, L. 登録日 2008-01-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase Nucleic Acids Res., 36, 2008
2J10	p53 tetramerization domain mutant T329F Q331K 分子名称: CELLULAR TUMOR ANTIGEN P53 著者 Carbajo, R.J, Mora, P, Sanchez del Pino, M.M, Perez-Paya, E, Pineda-Lucena, A. 登録日 2006-08-08 公開日 2007-08-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach. Proteins, 71, 2008
2ZHR	Crystal structure of BACE1 in complex with OM99-2 at pH 5.0 分子名称: Beta-secretase 1, inhibitor OM99-2 著者 Shimizu, H, Nukina, N. 登録日 2008-02-08 公開日 2008-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production Mol.Cell.Biol., 28, 2008
2J5W	Ceruloplasmin revisited: structural and functional roles of various metal cation binding sites 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CERULOPLASMIN, ... 著者 Bento, I, Peixoto, C, Zaitsev, V.N, Lindley, P.F. 登録日 2006-09-19 公開日 2007-02-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ceruloplasmin Revisited: Structural and Functional Roles of Various Metal Cation-Binding Sites. Acta Crystallogr.,Sect.D, 63, 2007
2VWV	ephB4 kinase domain inhibitor complex 分子名称: EPHRIN TYPE-B RECEPTOR 4, N'-(3-CHLORO-4-METHOXY-PHENYL)-N-(3,4,5-TRIMETHOXYPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE 著者 Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Kettle, J.G, Leach, A.G. 登録日 2008-06-27 公開日 2008-07-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Inhibitors of the Tyrosine Kinase Ephb4. Part 1: Structure-Based Design and Optimization of a Series of 2,4-Bis-Anilinopyrimidines Bioorg.Med.Chem.Lett., 18, 2008
2J1W	Human p53 core domain mutant M133L-V143A-V203A-N239Y-N268D 分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C, Fersht, A.R. 登録日 2006-08-15 公開日 2006-09-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs. Proc.Natl.Acad.Sci.USA, 103, 2006
2J0Y	L-ficolin complexed to b-1,3-D-glucan 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... 著者 Garlatti, V, Gaboriaud, C. 登録日 2006-08-08 公開日 2007-01-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
2W8N	The crystal structure of the oxidized form of human SSADH 分子名称: SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL, SULFATE ION 著者 Kim, Y.-G, Kim, K.-J. 登録日 2009-01-19 公開日 2009-06-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Redox-Switch Modulation of Human Ssadh by Dynamic Catalytic Loop. Embo J., 28, 2009
3FZZ	Structure of GrC 分子名称: Granzyme C, SULFATE ION 著者 Buckle, A.M, Kaiserman, D, Whisstock, J.C. 登録日 2009-01-27 公開日 2009-03-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of granzyme C reveals an unusual mechanism of protease autoinhibition Proc.Natl.Acad.Sci.USA, 106, 2009
2W3O	Crystal structure of the human PNKP FHA domain in complex with an XRCC1-derived phosphopeptide 分子名称: BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, CALCIUM ION, DNA REPAIR PROTEIN XRCC1 著者 Oliver, A.W, Ali, A.A.E, Pearl, L.H. 登録日 2008-11-13 公開日 2009-02-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Specific Recognition of a Multiply Phosphorylated Motif in the DNA Repair Scaffold Xrcc1 by the Fha Domain of Human Pnk. Nucleic Acids Res., 37, 2009
2W4J	X-ray structure of a DAP-Kinase 2-277 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, DEATH-ASSOCIATED PROTEIN KINASE 1, ... 著者 De Diego, I, Kuper, J, Lehmann, F, Wilmanns, M. 登録日 2008-11-27 公開日 2009-12-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 X-Ray Structure of a Dap-Kinase Calmodulin Complex To be Published
2WC0	crystal structure of human insulin degrading enzyme in complex with iodinated insulin 分子名称: 1,4-DIETHYLENE DIOXIDE, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Manolopoulou, M, Guo, Q, Malito, E, Schilling, A.B, Tang, W.J. 登録日 2009-03-06 公開日 2009-03-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme. J.Biol.Chem., 284, 2009
2KSR	NMR structures of TM domain of the n-Acetylcholine receptor b2 subunit 分子名称: Neuronal acetylcholine receptor subunit beta-2 著者 Bondarenko, V, Tillman, T, Xu, Y, Tang, P. 登録日 2010-01-12 公開日 2010-06-16 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the transmembrane domain of the n-acetylcholine receptor beta2 subunit. Biochim.Biophys.Acta, 1798, 2010
2WGX	HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-Y236F-N239Y-T253I-N268D 分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C, Khoo, K.H, Fersht, A.R. 登録日 2009-04-27 公開日 2009-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Stabilising the DNA-Binding Domain of P53 by Rational Design of its Hydrophobic Core. Protein Eng.Des.Sel., 22, 2009
2KUM	Solution structure of the human chemokine CCL27 分子名称: C-C motif chemokine 27 著者 Kirkpatrick, J.P, Jansma, A, Hsu, A, Handel, T.M, Nietlispach, D. 登録日 2010-02-22 公開日 2010-03-02 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 NMR analysis of the structure, dynamics, and unique oligomerization properties of the chemokine CCL27. J.Biol.Chem., 285, 2010
3B38	Structure of A104V DJ-1 分子名称: 1,2-ETHANEDIOL, Protein DJ-1 著者 Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. 登録日 2007-10-19 公開日 2008-01-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1. Biochemistry, 47, 2008
2W4R	Crystal structure of the regulatory domain of human LGP2 分子名称: MERCURY (II) ION, PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, SULFATE ION 著者 Pippig, D.A, Hellmuth, J.C, Cui, S, Kirchhofer, A, Lammens, K, Lammens, A, Schmidt, A, Rothenfusser, S, Hopfner, K.P. 登録日 2008-12-01 公開日 2009-02-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA. Nucleic Acids Res., 37, 2009
3B3W	Crystal structure of the S228A mutant of the aminopeptidase from Vibrio proteolyticus in complex with leucine 分子名称: Bacterial leucyl aminopeptidase, LEUCINE, SODIUM ION, ... 著者 Ataie, N.J, Hoang, Q.Q, Zahniser, M.P.D, Milne, A, Petsko, G.A, Ringe, D. 登録日 2007-10-22 公開日 2007-11-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus. Biochemistry, 47, 2008
3B4F	Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies 分子名称: 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Guzel, o, Temperini, c, Innocenti, a, Scozzafava, A, Salman, a, Supuran, c.t. 登録日 2007-10-24 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 18, 2008
2VOK	Murine TRIM21 分子名称: 52 KDA RO PROTEIN 著者 Keeble, A.H, Khan, Z, Forster, A, James, L.C. 登録日 2008-02-19 公開日 2008-04-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Trim21 is an Igg Receptor that is Structurally, Thermodynamically, and Kinetically Conserved. Proc.Natl.Acad.Sci.USA, 105, 2008
2KR6	Solution structure of presenilin-1 CTF subunit 分子名称: Presenilin-1 著者 Doetsch, V. 登録日 2009-12-04 公開日 2010-04-28 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Solution structure of presenilin-1 CTF subunit To be Published

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