PDB: 245663 件ウェブページステータス検索Chemie searchBIRD

---

4DFS	Structure of the catalytic domain of an endo-1,3-beta-glucanase (laminarinase) from Thermotoga petrophila RKU-1 分子名称: CALCIUM ION, Glycoside hydrolase, family 16, ... 著者 Meza, A.N, Ruller, R, Prade, R.A, Squina, F.M, Santos, C.R, Murakami, M.T. 登録日 2012-01-24 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.754 Å) 主引用文献 Structural studies of an endo-1,3-beta-glucanase from Thermotoga petrophila RKU-1 To be Published
1VET	Crystal Structure of p14/MP1 at 1.9 A resolution 分子名称: Late endosomal/lysosomal Mp1 interacting protein, Mitogen-activated protein kinase kinase 1 interacting protein 1 著者 Kurzbauer, R, Teis, D, Maurer-Stroh, S, Eisenhaber, F, Hekman, M, Bourenkov, G.P, Bartunik, H.D, Huber, L.A, Clausen, T. 登録日 2004-04-05 公開日 2004-08-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the p14/MP1 scaffolding complex: How a twin couple attaches mitogen- activated protein kinase signaling to late endosomes Proc.Natl.Acad.Sci.USA, 101, 2004
1VMA	Crystal structure of Cell division protein ftsY (TM0570) from Thermotoga maritima at 1.60 A resolution 分子名称: CITRIC ACID, MAGNESIUM ION, cell division protein FtsY 著者 Joint Center for Structural Genomics (JCSG) 登録日 2004-09-15 公開日 2004-09-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of Cell division protein ftsY (TM0570) from Thermotoga maritima at 1.60 A resolution To be published
3M6G	Crystal structure of actin in complex with lobophorolide 分子名称: (1S,3S,4S,5S,7R,8S,9R,12E,14E,16R,17R,19R)-16-hydroxy-9-{(1S,2S,3S)-2-hydroxy-5-[(2S,4R,6S)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl]-1,3-dimethylpentyl}-3,5,7,17-tetramethoxy-8,14-dimethyl-11H-spiro[10,23-dioxabicyclo[17.3.1]tricosa-12,14,20-triene-4,2'-oxiran]-11-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Allingham, J.S. 登録日 2010-03-15 公開日 2010-09-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Two molecules of lobophorolide cooperate to stabilize an actin dimer using both their "ring" and "tail" region. Chem.Biol., 17, 2010
180L	PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME 分子名称: LYSOZYME 著者 Kuroki, R, Weaver, L, Zhang, X.-J, Matthews, B.W. 登録日 1995-03-24 公開日 1996-04-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme. J.Mol.Biol., 250, 1995
3NSW	Crystal Structure of Ancylostoma ceylanicum Excretory-Secretory Protein 2 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Excretory-secretory protein 2 著者 Kucera, K, Modis, Y. 登録日 2010-07-02 公開日 2011-05-18 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Ancylostoma ceylanicum Excretory-Secretory Protein 2 Adopts a Netrin-Like Fold and Defines a Novel Family of Nematode Proteins. J.Mol.Biol., 408, 2011
6B7F	Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with (R)-3,3-dimethyl-4-(5-vinyl-1H-imidazol-1-yl)isochroman-1-one 分子名称: (4R)-4-(5-ethenyl-1H-imidazol-1-yl)-3,3-dimethyl-3,4-dihydro-1H-2-benzopyran-1-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, ... 著者 Proudfoot, A.W, Bussiere, D, Lingel, A. 登録日 2017-10-03 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.562 Å) 主引用文献 High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
1GOK	Thermostable xylanase I from Thermoascus aurantiacus- Crystal form II 分子名称: ENDO-1,4-BETA-XYLANASE 著者 Lo Leggio, L, Pickersgill, R.W. 登録日 2001-10-22 公開日 2001-10-25 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Substrate Specificity and Subsite Mobility in T. Aurantiacus Xylanase 10A FEBS Lett., 509, 2001
1RL4	Plasmodium falciparum peptide deformylase complex with inhibitor 分子名称: (2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID, 2-{N'-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE, COBALT (II) ION, ... 著者 Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G.J. 登録日 2003-11-24 公開日 2003-12-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 An improved crystal form of Plasmodium falciparum peptide deformylase. Protein Sci., 13, 2004
4AOK	Conformational dynamics of aspartate alpha-decarboxylase active site revealed by protein-ligand complexes: 1-methyl-L-aspartate complex 分子名称: ASPARTATE 1-DECARBOXYLASE ALPHA CHAIN, ASPARTATE 1-DECARBOXYLASE BETA CHAIN 著者 Yorke, B.A, Monteiro, D.C.F, Pearson, A.R, Webb, M.E. 登録日 2012-03-28 公開日 2012-10-31 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conformational Dynamics of Aspartate Alpha Decarboxylase Active Site Revealed by Protein-Ligand Complexes To be Published
4HBA	Structural and Catalytic Characterization of a Thermal and Acid Stable Variant of Human Carbonic Anhydrase II Containing an Engineered Disulfide Bond 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 Boone, C.D, Habibzadegan, A, McKenna, R. 登録日 2012-09-27 公開日 2013-07-31 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 Structural and catalytic characterization of a thermally stable and acid-stable variant of human carbonic anhydrase II containing an engineered disulfide bond. Acta Crystallogr.,Sect.D, 69, 2013
7DB8	Crystal structure of Mycobacterium tuberculosis phenylalanyl-tRNA synthetase in complex with compound PF-3845 分子名称: N-pyridin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methyl]piperidine-1-carboxamide, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit, ... 著者 Xu, M, Zhang, X, Xu, L, Chen, S. 登録日 2020-10-19 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis . J.Biol.Chem., 2021
7DEN	Crystal structure of P.aeruginosa LpxC in complex with inhibitor 分子名称: 4-[(1~{R},5~{S})-6-[2-[4-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]phenyl]ethynyl]-3-azabicyclo[3.1.0]hexan-3-yl]butanoic acid, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION 著者 Mima, M, Ushiyama, F, Takashima, H. 登録日 2020-11-04 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg.Med.Chem., 30, 2020
1A7D	CHLOROMET MYOHEMERYTHRIN FROM THEMISTE ZOSTERICOLA 分子名称: CHLORIDE ION, CHLORO DIIRON-OXO MOIETY, MYOHEMERYTHRIN 著者 Martins, L.J, Hill, C.P, Ellis Junior, W.R. 登録日 1998-03-12 公開日 1998-10-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of wild-type chloromet and L103N hydroxomet Themiste zostericola myohemerythrins at 1.8 A resolution. Biochemistry, 36, 1997
7DEL	Crystal structure of P.aeruginosa LpxC in complex with inhibitor 分子名称: 3-[4-[2-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]ethynyl]phenyl]propan-1-ol, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION 著者 Mima, M, Ushiyama, F, Tanaka-Yamamoto, N. 登録日 2020-11-04 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg.Med.Chem., 30, 2020
7DEM	Crystal structure of P.aeruginosa LpxC in complex with inhibitor 分子名称: 5-[4-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]phenyl]pent-4-yn-1-ol, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION 著者 Mima, M, Ushiyama, F, Matsuda, Y. 登録日 2020-11-04 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg.Med.Chem., 30, 2020
4AMZ	PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN WITH A COVALENTLY BOUND INHIBITOR IC-2 分子名称: (5R)-N-benzyl-5-({(2S)-2-[(1R)-1,2-dihydroxyethyl]pyrrolidin-1-yl}carbonyl)cyclopent-1-ene-1-carboxamide, GLYCEROL, PROLYL ENDOPEPTIDASE 著者 Kaszuba, K, Rog, T, Danne, R, Canning, P, Fulop, V, Juhasz, T, Szeltner, Z, St-Pierre, J.F, Garcia-Horsman, A, Mannisto, P.T, Karttunen, M, Hokkanen, J, Bunker, A. 登録日 2012-03-14 公開日 2012-05-16 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular Dynamics, Crystallography and Mutagenesis Studies on the Substrate Gating Mechanism of Prolyl Oligopeptidase. Biochimie, 94, 2012
4FJR	Mode of interaction of Merocyanine 540 with HEW Lysozyme 分子名称: 3-[(2E)-2-[(2Z)-4-(1,3-dibutyl-4,6-dioxo-2-thioxotetrahydropyrimidin-5(2H)-ylidene)but-2-en-1-ylidene]-1,3-benzoxazol-3(2H)-yl]propane-1-sulfonic acid, CHLORIDE ION, Lysozyme C 著者 Mitra, P, Banerjee, M, Basu, S, Biswas, S. 登録日 2012-06-12 公開日 2013-07-03 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Mode of interaction of Merocyanine 540 dye with lysozyme To be Published
3OBQ	Crystal Structure of the Tsg101 UEV domain in complex with a human HRS PSAP peptide 分子名称: Hepatocyte growth factor-regulated tyrosine kinase substrate, Tumor susceptibility gene 101 protein 著者 Im, Y.J, Hurley, J.H. 登録日 2010-08-09 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction. Structure, 18, 2010
1Z7S	The crystal structure of coxsackievirus A21 分子名称: CALCIUM ION, GUANOSINE-5'-MONOPHOSPHATE, Human COXSACKIEVIRUS A21, ... 著者 Xiao, C, Bator-Kelly, C.M, Rieder, E, Chipman, P.R, Craig, A, Kuhn, R.J, Wimmer, E, Rossmann, M.G. 登録日 2005-03-28 公開日 2005-08-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The crystal structure of coxsackievirus a21 and its interaction with icam-1. Structure, 13, 2005
2O3G	Structural Genomics, the crystal structure of a conserved putative domain from Neisseria meningitidis MC58 分子名称: 1,2-ETHANEDIOL, Putative protein 著者 Tan, K, Volkart, L, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2006-12-01 公開日 2007-01-02 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The crystal structure of a conserved putative domain from Neisseria meningitidis MC58 To be Published
7FUF	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one 分子名称: (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION 著者 Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. 登録日 2023-02-08 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.919 Å) 主引用文献 Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
1RGU	The crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate, octopamine, and tetranucleotide AGTG 分子名称: 4-(2S-AMINO-1-HYDROXYETHYL)PHENOL, 5'-D(*AP*GP*TP*G)-3', SPERMINE, ... 著者 Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G. 登録日 2003-11-13 公開日 2004-03-02 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes. J.Med.Chem., 47, 2004
3O23	Human unphosphorylated IGF1-R Kinase domain in complex with an hydantoin inhibitor 分子名称: (5S)-5-methyl-1-(quinolin-4-ylmethyl)-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione, Insulin-like growth factor 1 receptor 著者 Maignan, S, Guilloteau, J.P, Dupuy, A. 登録日 2010-07-22 公開日 2011-05-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: Advantages in comparison with competitive inhibitors Bioorg.Med.Chem.Lett., 21, 2011
7FUG	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one 分子名称: (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION 著者 Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. 登録日 2023-02-08 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.106 Å) 主引用文献 Crystal Structure of a human cyclic GMP-AMP synthase complex To be published

<2615261626172618261926202621262226232624262526262627262826292630>