7FTU
 
 | | Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-N-[4-(4-chlorophenyl)sulfonylphenyl]-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide | | 分子名称: | (2Z)-N-[4-(4-chlorobenzene-1-sulfonyl)phenyl]-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... | | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. | | 登録日 | 2023-02-08 | | 公開日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
|
|
4KTB
 | | The crystal structure of posible asymmetric diadenosine tetraphosphate (Ap(4)A) hydrolases from Jonesia denitrificans DSM 20603 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Putative uncharacterized protein, ... | | 著者 | Tan, K, Kim, Y, Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2013-05-20 | | 公開日 | 2013-06-05 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.936 Å) | | 主引用文献 | The crystal structure of posible asymmetric diadenosine tetraphosphate (Ap(4)A) hydrolases from Jonesia denitrificans DSM 20603
To be Published
|
|
3O5X
 | | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor | | 分子名称: | 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J. | | 登録日 | 2010-07-28 | | 公開日 | 2010-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
J.Med.Chem., 53, 2010
|
|
1DVB
 | | RUBRERYTHRIN | | 分子名称: | FE (III) ION, RUBRERYTHRIN, ZINC ION | | 著者 | Sieker, L.C, Holmes, M, Le Trong, I, Turley, S, Liu, M.Y, Legall, J, Stenkamp, R.E. | | 登録日 | 2000-01-20 | | 公開日 | 2000-11-17 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The 1.9 A crystal structure of the "as isolated" rubrerythrin from Desulfovibrio vulgaris: some surprising results.
J.Biol.Inorg.Chem., 5, 2000
|
|
2QX2
 | | Structure of the C-terminal domain of sex pheromone staph-cAM373 precursor from Staphylococcus aureus | | 分子名称: | 1,2-ETHANEDIOL, Sex pheromone staph-cAM373 | | 著者 | Cuff, M.E, Mussar, K, Hatzos, C, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-08-10 | | 公開日 | 2007-09-11 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the C-terminal domain of sex pheromone staph-cAM373 precursor from Staphylococcus aureus.
TO BE PUBLISHED
|
|
4K55
 | |
1K6A
 | | Structural studies on the mobility in the active site of the Thermoascus aurantiacus xylanase I | | 分子名称: | xylanase I | | 著者 | Lo Leggio, L, Kalogiannis, S, Eckert, K, Teixeira, S.C.M, Bhat, M.K, Andrei, C, Pickersgill, R.W, Larsen, S. | | 登録日 | 2001-10-15 | | 公開日 | 2002-07-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Substrate specificity and subsite mobility in T. aurantiacus xylanase 10A.
FEBS LETT., 509, 2001
|
|
3BPJ
 | | Crystal structure of human translation initiation factor 3, subunit 1 alpha | | 分子名称: | Eukaryotic translation initiation factor 3 subunit J, UNKNOWN ATOM OR ION | | 著者 | Tempel, W, Nedyalkova, L, Hong, B, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2007-12-18 | | 公開日 | 2008-01-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of human translation initiation factor 3, subunit 1 alpha.
To be Published
|
|
1SR6
 | | Structure of nucleotide-free scallop myosin S1 | | 分子名称: | CALCIUM ION, MAGNESIUM ION, Myosin essential light chain, ... | | 著者 | Risal, D, Gourinath, S, Himmel, D.M, Szent-Gyorgyi, A.G, Cohen, C. | | 登録日 | 2004-03-22 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding.
Proc.Natl.Acad.Sci.Usa, 101, 2004
|
|
4KIQ
 | |
4GJ4
 | |
1DTS
 | | CRYSTAL STRUCTURE OF AN ATP DEPENDENT CARBOXYLASE, DETHIOBIOTIN SYNTHASE, AT 1.65 ANGSTROMS RESOLUTION | | 分子名称: | DETHIOBIOTIN SYNTHETASE | | 著者 | Huang, W, Lindqvist, Y, Schneider, G. | | 登録日 | 1995-03-28 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of an ATP-dependent carboxylase, dethiobiotin synthetase, at 1.65 A resolution.
Structure, 2, 1994
|
|
4KQD
 | |
4GNF
 | | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15 | | 分子名称: | Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION | | 著者 | Li, F, He, C, Wu, J, Shi, Y. | | 登録日 | 2012-08-17 | | 公開日 | 2013-01-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
|
|
4C6U
 | | Crystal structure of M. tuberculosis KasA in complex with TLM5 | | 分子名称: | (5R)-3-acetyl-4-hydroxy-5-methyl-5-[(1Z)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one, 1,2-ETHANEDIOL, 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, ... | | 著者 | Schiebel, J, Kapilashrami, K, Fekete, A, Bommineni, G.R, Schaefer, C.M, Mueller, M.J, Tonge, P.J, Kisker, C. | | 登録日 | 2013-09-19 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis for the Recognition of Mycolic Acid Precursors by Kasa, a Condensing Enzyme and Drug Target from Mycobacterium Tuberculosis
J.Biol.Chem., 288, 2013
|
|
1SDE
 | | Toward Better Antibiotics: Crystal Structure Of D-Ala-D-Ala Peptidase inhibited by a novel bicyclic phosphate inhibitor | | 分子名称: | 2-[(DIOXIDOPHOSPHINO)OXY]BENZOATE, D-alanyl-D-alanine carboxypeptidase, GLYCEROL | | 著者 | Silvaggi, N.R, Kaur, K, Adediran, S.A, Pratt, R.F, Kelly, J.A. | | 登録日 | 2004-02-13 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors
Biochemistry, 43, 2004
|
|
1SL8
 | | Calcium-loaded apo-aequorin from Aequorea victoria | | 分子名称: | Aequorin 1, CALCIUM ION | | 著者 | Deng, L, Markova, S.V, Vysotski, E.S, Liu, Z.J, Lee, J, Rose, J, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2004-03-05 | | 公開日 | 2004-12-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin.
Protein Sci., 14, 2005
|
|
1UFI
 | | Crystal structure of the dimerization domain of human CENP-B | | 分子名称: | Major centromere autoantigen B | | 著者 | Tawaramoto, M.S, Kurumizaka, H, Tanaka, Y, Park, S.-Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-05-30 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of the human centromere protein B (CENP-B) dimerization domain at 1.65-A resolution
J.Biol.Chem., 278, 2003
|
|
1S9U
 | | Atomic structure of a putative anaerobic dehydrogenase component | | 分子名称: | DI(HYDROXYETHYL)ETHER, SULFATE ION, putative component of anaerobic dehydrogenases | | 著者 | Qiu, Y, Zhang, R, Tereshko, V, Kim, Y, Collart, F, Joachimiak, A, Kossiakoff, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-02-05 | | 公開日 | 2004-06-08 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | The 1.38 A crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway.
Proteins, 71, 2008
|
|
4I23
 | | Crystal structure of the wild-type EGFR kinase domain in complex with dacomitinib (soaked) | | 分子名称: | (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide, Epidermal growth factor receptor | | 著者 | Gajiwala, K.S, Feng, J, Ferre, R, Ryan, K, Brodsky, O, Stewart, A. | | 登録日 | 2012-11-21 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Insights into the Aberrant Activity of Mutant EGFR Kinase Domain and Drug Recognition.
Structure, 21, 2013
|
|
1OT5
 | | The 2.4 Angstrom Crystal Structure of Kex2 in complex with a peptidyl-boronic acid inhibitor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ac-Ala-Lys-boroArg N-acetylated boronic acid peptide inhibitor, ... | | 著者 | Holyoak, T, Wilson, M.A, Fenn, T.D, Kettner, C.A, Petsko, G.A, Fuller, R.S, Ringe, D. | | 登録日 | 2003-03-21 | | 公開日 | 2003-06-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 2.4 A Resolution Crystal Structure of the Prototypical Hormone-Processing Protease Kex2 in Complex with an Ala-Lys-Arg Boronic Acid Inhibitor
Biochemistry, 42, 2003
|
|
4GNE
 | | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7 | | 分子名称: | Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION | | 著者 | Li, F, He, C, Wu, J, Shi, Y. | | 登録日 | 2012-08-17 | | 公開日 | 2013-01-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
|
|
4GNG
 | | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide | | 分子名称: | GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase NSD3, ... | | 著者 | Li, F, He, C, Wu, J, Shi, Y. | | 登録日 | 2012-08-17 | | 公開日 | 2013-01-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
|
|
4GDY
 | | Kynurenine Aminotransferase II inhibitors | | 分子名称: | (5-hydroxy-6-methyl-4-{[(1-oxo-7-phenoxy-1,2-dihydro[1,2,4]triazolo[4,3-a]quinolin-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | | 著者 | Pandit, J. | | 登録日 | 2012-08-01 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Discovery of Hydroxamate Bioisosteres as KATII Inhibitors with Improved Oral Bioavailability and Pharmacokinetics
MEDCHEMCOMM, 2012
|
|
1SJR
 | | NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1) | | 分子名称: | Polypyrimidine tract-binding protein 1 | | 著者 | Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J. | | 登録日 | 2004-03-04 | | 公開日 | 2004-09-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and RNA Interactions of the N-Terminal RRM Domains of PTB
Structure, 12, 2004
|
|
