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2Z8K
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Crystal Structure of Escherichia coli gamma-Glutamyltranspeptidase in Complex with Acivicin
分子名称: (2S)-AMINO[(5S)-3-CHLORO-4,5-DIHYDROISOXAZOL-5-YL]ACETIC ACID, Gamma-glutamyltranspeptidase
著者Wada, K, Irie, M, Fukuyama, K.
登録日2007-09-05
公開日2008-06-24
最終更新日2012-04-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists
J.Mol.Biol., 380, 2008
2KAV
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BU of 2kav by Molmil
Solution structure of the human Voltage-gated Sodium Channel, brain isoform (Nav1.2)
分子名称: Sodium channel protein type 2 subunit alpha
著者Miloushev, V.Z, Levine, J.A, Arbing, M.A, Hunt, J.F, Pitt, G.S, Palmer, A.G.
登録日2008-11-15
公開日2009-01-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the NaV1.2 C-terminal EF-hand domain.
J.Biol.Chem., 284, 2009
2KLJ
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BU of 2klj by Molmil
Solution Structure of gammaD-Crystallin with RDC and SAXS
分子名称: Gamma-crystallin D
著者Wang, J, Zuo, X, Yu, P, Byeon, I, Jung, J, Gronenborn, A.M, Wang, Y.
登録日2009-07-06
公開日2009-10-06
最終更新日2024-05-22
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
2KDG
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Solution Structure of the 1st Ig domain of Myotilin
分子名称: Myotilin
著者Heikkinen, O, Kilpelainen, I, Permi, P, Koskela, H, Ylanne, J, Carpen, O.
登録日2009-01-08
公開日2009-07-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the first immunoglobulin domain of human myotilin
J.Biomol.Nmr, 44, 2009
2Z6H
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BU of 2z6h by Molmil
Crystal Structure of Beta-Catenin Armadillo Repeat Region and Its C-Terminal domain
分子名称: Catenin beta-1
著者Xing, Y, Takemaru, K, Liu, J, Zheng, J, Moon, R, Xu, W.
登録日2007-08-01
公開日2008-02-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of a Full-Length beta-Catenin
Structure, 16, 2008
2K58
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BU of 2k58 by Molmil
NMR structures of the first transmembrane domain of the neuronal acetylcholine receptor beta 2 subunit
分子名称: Neuronal acetylcholine receptor subunit beta-2
著者Bondarenko, V, Tang, P, Xu, Y.
登録日2008-06-25
公開日2008-07-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the first transmembrane domain of the neuronal acetylcholine receptor beta 2 subunit
Biophys.J., 92, 2007
2KES
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BU of 2kes by Molmil
Solution Structure of the Coiled-coil Domain of Synphilin-1
分子名称: Synphilin-1
著者Xie, Y.Y, Zhou, C.J, Zhou, Z.R, Hu, H.Y.
登録日2009-02-02
公開日2009-02-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication.
Faseb J., 24, 2010
2K6N
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BU of 2k6n by Molmil
Solution Structure of Human Supervillin Headpiece, Minimized Average
分子名称: Supervillin
著者Brown, J.W, Didem, V, McKnight, C.
登録日2008-07-11
公開日2009-07-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献How to arm a supervillin: designing F-actin binding activity into supervillin headpiece.
J.Mol.Biol., 393, 2009
2ZE1
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BU of 2ze1 by Molmil
X-ray structure of Bace-1 in complex with compound 6g
分子名称: 3-bromo-N-[4-[1-(2-carbamimidamido-2-oxo-ethyl)-5-phenyl-pyrrol-2-yl]phenyl]benzamide, Beta-secretase 1
著者Chopra, R, Olland, A.
登録日2007-12-05
公開日2008-12-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets.
Bioorg.Med.Chem.Lett., 18, 2008
2KFT
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BU of 2kft by Molmil
NMR Solution structure of the first PHD finger domain of human Autoimmune Regulator (AIRE) in complex with Histone H3(1-20Cys) Peptide
分子名称: Autoimmune regulator, Histone H3, ZINC ION
著者Chakravarty, S, Zeng, L, Zhou, M.
登録日2009-02-27
公開日2009-04-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator.
Structure, 17, 2009
2KGB
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BU of 2kgb by Molmil
NMR solution of the regulatory domain cardiac F77W-Troponin C in complex with the cardiac Troponin I 144-163 switch peptide
分子名称: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
著者Mercier, P, Julien, O, Crane, M.L, Sykes, B.D.
登録日2009-03-07
公開日2009-03-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C.
Protein Sci., 18, 2009
2VL3
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BU of 2vl3 by Molmil
Oxidized and reduced forms of human peroxiredoxin 5
分子名称: PEROXIREDOXIN-5
著者Smeets, A, Declercq, J.P.
登録日2008-01-08
公開日2008-08-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献The Crystal Structures of Oxidized Forms of Human Peroxiredoxin 5 with an Intramolecular Disulfide Bond Confirm the Proposed Enzymatic Mechanism for Atypical 2-Cys Peroxiredoxins.
Arch.Biochem.Biophys., 477, 2008
2ZFT
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BU of 2zft by Molmil
Exploring trypsin S3 pocket
分子名称: (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ...
著者Brandt, T, Baum, B, Heine, A, Klebe, G.
登録日2008-01-11
公開日2009-01-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
2K6D
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BU of 2k6d by Molmil
CIN85 Sh3-C domain in complex with ubiquitin
分子名称: SH3 domain-containing kinase-binding protein 1, Ubiquitin
著者Forman-Kay, J, Bezsonova, I.
登録日2008-07-07
公開日2008-08-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination.
Biochemistry, 47, 2008
2V7A
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BU of 2v7a by Molmil
Crystal structure of the T315I Abl mutant in complex with the inhibitor PHA-739358
分子名称: MAGNESIUM ION, N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1
著者Modugno, M, Casale, E, Soncini, C, Rosettani, P, Colombo, R, Lupi, R, Rusconi, L, Fancelli, D, Carpinelli, P, Cameron, A.D, Isacchi, A, Moll, J.
登録日2007-07-27
公開日2007-09-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor Pha-739358.
Cancer Res., 67, 2007
2K7Q
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BU of 2k7q by Molmil
Filamin A Ig-like domains 18-19
分子名称: Filamin-A
著者Heikkinen, O.K, Kilpelainen, I, Koskela, H, Permi, P, Heikkinen, S, Ylanne, J.
登録日2008-08-19
公開日2009-07-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin
J.Biol.Chem., 284, 2009
2KAP
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BU of 2kap by Molmil
Solution structure of DLC1-SAM
分子名称: Rho GTPase-activating protein 7
著者Yang, S, Yang, D.
登録日2008-11-12
公開日2009-10-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Characterization of DLC1-SAM equilibrium unfolding at the amino acid residue level
Biochemistry, 48, 2009
2V3E
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BU of 2v3e by Molmil
acid-beta-glucosidase with N-nonyl-deoxynojirimycin
分子名称: (2R,3R,4R,5S)-2-(HYDROXYMETHYL)-1-NONYLPIPERIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUCOSYLCERAMIDASE, ...
著者Brumshtein, B, Greenblatt, H.M, Butters, T.D, Shaaltiel, Y, Aviezer, D, Silman, I, Futerman, A.H, Sussman, J.L.
登録日2007-06-17
公開日2007-08-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid Beta-Glucosidase: Insights Into the Mechanism of Chemical Chaperone Action in Gaucher Disease.
J.Biol.Chem., 282, 2007
2ZZ0
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BU of 2zz0 by Molmil
Crystal structure of human thioredoxin reductase I (SeCys 498 Cys)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Thioredoxin reductase 1, ...
著者Lo, Y.C, Ko, T.P, Wang, A.H.J.
登録日2009-02-02
公開日2009-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Terpyridine-platinum(II) complexes are effective inhibitors of mammalian topoisomerases and human thioredoxin reductase 1.
J.Inorg.Biochem., 103, 2009
2KKI
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Solution structure of human Interleukin 1a
分子名称: Interleukin-1 alpha
著者Mohan, S.K, Chang, H.-K, Yu, C.
登録日2009-06-24
公開日2010-06-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献1H, 13C and 15N backbone and side chain resonance assignments of human interleukin 1alpha
Biomol.Nmr Assign., 4, 2010
2ZZB
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BU of 2zzb by Molmil
Crystal structure of human thioredoxin reductase I and terpyridine platinum(II)
分子名称: 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
著者Lo, Y.C, Ko, T.P, Wang, A.H.J.
登録日2009-02-09
公開日2009-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Terpyridine-platinum(II) complexes are effective inhibitors of mammalian topoisomerases and human thioredoxin reductase 1.
J.Inorg.Biochem., 103, 2009
2KC3
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NMR solution structure of complete receptor binding domain of human apolipoprotein E
分子名称: Apolipoprotein E
著者Wang, J, Sivashanmugam, A.
登録日2008-12-15
公開日2009-04-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A complete receptor binding domain of human apolipoprotein E
To be Published
2KK6
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Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d
分子名称: Proto-oncogene tyrosine-protein kinase FER
著者Tang, Y, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2009-06-15
公開日2009-08-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d
To be Published
2KLD
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Solution Structure of the Calcium Binding Domain of the C-terminal Cytosolic Domain of Polycystin-2
分子名称: Polycystin-2
著者Kalbitzer, H.R.
登録日2009-07-01
公開日2009-07-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR-assignments of a cytosolic domain of the C-terminus of polycystin-2
Biomol.Nmr Assign., 3, 2009
2UZX
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Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein InlB: Crystal form I
分子名称: HEPATOCYTE GROWTH FACTOR RECEPTOR, INTERNALIN B
著者Niemann, H.H, Jager, V, Butler, P.J.G, Van Den Heuvel, J, Schmidt, S, Ferraris, D, Gherardi, E, Heinz, D.W.
登録日2007-05-02
公開日2007-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Human Receptor Tyrosine Kinase met in Complex with the Listeria Invasion Protein Inlb
Cell(Cambridge,Mass.), 130, 2007

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