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2Z5S
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BU of 2z5s by Molmil
Molecular basis for the inhibition of p53 by Mdmx
分子名称: Cellular tumor antigen p53, Mdm4 protein
著者Popowicz, G.M, Czarna, A, Rothweiler, U, Szwagierczak, A, Holak, T.A.
登録日2007-07-17
公開日2007-11-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for the inhibition of p53 by Mdmx.
Cell Cycle, 6, 2007
2WVR
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BU of 2wvr by Molmil
Human Cdt1:Geminin complex
分子名称: DNA REPLICATION FACTOR CDT1, GEMININ
著者De Marco, V, Perrakis, A.
登録日2009-10-19
公開日2009-10-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Quaternary Structure of the Human Cdt1-Geminin Complex Regulates DNA Replication Licensing.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WIG
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BU of 2wig by Molmil
NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Carletti, E, Aurbek, N, Gillon, E, Loiodice, M, Nicolet, Y, Fontecilla, J, Masson, P, Thiermann, H, Nachon, F, Worek, F.
登録日2009-05-11
公開日2009-05-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
Biochem. J., 421, 2009
2J4A
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BU of 2j4a by Molmil
Human Thyroid hormone receptor beta ligand binding domain in complex with KB131084
分子名称: 3,5-DIBROMO-4-(3-ISOPROPYL-PHENOXY)BENZOIC ACID, THYROID HORMONE RECEPTOR BETA-1
著者Farnegardh, M.
登録日2006-08-28
公開日2007-09-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Thyroid Receptor Ligands. 6. A High Affinity "Direct Antagonist" Selective for the Thyroid Hormone Receptor.
J.Med.Chem., 49, 2006
2ZDK
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BU of 2zdk by Molmil
Exploring Trypsin S3 Pocket
分子名称: (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ...
著者Baum, B, Brandt, T, Heine, A, Klebe, G.
登録日2007-11-26
公開日2008-10-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
2WJW
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BU of 2wjw by Molmil
Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 1.8 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ...
著者Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R.
登録日2009-06-01
公開日2009-08-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors.
J.Mol.Biol., 392, 2009
2ZDV
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BU of 2zdv by Molmil
Exploring Thrombin S1 pocket
分子名称: D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide, Hirudin variant-1, PHOSPHATE ION, ...
著者Baum, B, Heine, A, Klebe, G.
登録日2007-11-29
公開日2008-10-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Exploring Thrombin S1 pocket
To be Published
2ZGJ
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BU of 2zgj by Molmil
Crystal Structure of D86N-GzmM Complexed with Its Optimal Synthesized Substrate
分子名称: Granzyme M, SSGKVPLS, SULFATE ION
著者Wu, L.F, Wang, L, Hua, G.Q, Liu, K, Zhai, Y.J, Sun, F, Fan, Z.S.
登録日2008-01-22
公開日2009-01-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M
J.Immunol., 183, 2009
2ZHV
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BU of 2zhv by Molmil
Crystal structure of BACE1 at pH 7.0
分子名称: Beta-secretase 1
著者Shimizu, H, Nukina, N.
登録日2008-02-08
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production
Mol.Cell.Biol., 28, 2008
2Z5T
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BU of 2z5t by Molmil
Molecular basis for the inhibition of p53 by Mdmx
分子名称: Cellular tumor antigen p53, Mdm4 protein
著者Popowicz, G.M, Czarna, A, Rothweiler, U, Szwagierczak, A, Holak, T.A.
登録日2007-07-17
公開日2007-11-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for the inhibition of p53 by Mdmx.
Cell Cycle, 6, 2007
2Z6O
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BU of 2z6o by Molmil
Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1
分子名称: MAGNESIUM ION, Ufm1-conjugating enzyme 1
著者Mizushima , T, Tatsumi, K, Ozaki, Y, Kawakami, T, Suzuki, A, Ogasahara, K, Komatsu, M, Kominami, E, Tanaka, K, Yamane, T.
登録日2007-08-06
公開日2007-09-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of Ufc1, the Ufm1-conjugating enzyme
Biochem.Biophys.Res.Commun., 362, 2007
2ZJ1
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BU of 2zj1 by Molmil
Crystal structure of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with NAD and 3'-keto-aristeromycin
分子名称: (2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentanone, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Reddy, M.C.M, Gokulan, K, Shetty, N.D, Owen, J.L, Ioerger, T.R, Sacchettini, J.C.
登録日2008-02-29
公開日2008-09-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors.
Protein Sci., 17, 2008
2ZK1
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BU of 2zk1 by Molmil
Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2
分子名称: (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, Peroxisome proliferator-activated receptor gamma
著者Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K.
登録日2008-03-12
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids
J.Mol.Biol., 385, 2009
2Z8I
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BU of 2z8i by Molmil
Crystal Structure of Escherichia coli Gamma-Glutamyltranspeptidase in Complex with Azaserine
分子名称: Gamma-glutamyltranspeptidase, O-DIAZOACETYL-L-SERINE
著者Wada, K, Irie, M, Fukuyama, K.
登録日2007-09-05
公開日2008-06-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists
J.Mol.Biol., 380, 2008
2ZLU
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BU of 2zlu by Molmil
Horse methemoglobin high salt, pH 7.0 (88% relative humidity)
分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
著者Kaushal, P.S, Sankaranarayanan, R, Vijayan, M.
登録日2008-04-10
公開日2008-06-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Water-mediated variability in the structure of relaxed-state haemoglobin
Acta Crystallogr.,Sect.F, 64, 2008
2ZLX
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BU of 2zlx by Molmil
Horse methemoglobin high salt, pH 7.0 (66% relative humidity)
分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
著者Kaushal, P.S, Sankaranarayanan, R, Vijayan, M.
登録日2008-04-10
公開日2008-06-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Water-mediated variability in the structure of relaxed-state haemoglobin
Acta Crystallogr.,Sect.F, 64, 2008
2WJ7
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BU of 2wj7 by Molmil
human alphaB crystallin
分子名称: ALPHA-CRYSTALLIN B CHAIN
著者Naylor, C.E, Bagneris, C, Bateman, O.A, Cronin, N, Keep, N.H, Slingsby, C.
登録日2009-05-22
公開日2009-08-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.631 Å)
主引用文献Crystal Structures of Alpha-Crystallin Domain Dimers of Alphab-Crystallin and Hsp20.
J.Mol.Biol., 392, 2009
2Z8V
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BU of 2z8v by Molmil
Structure of an IgNAR-AMA1 complex
分子名称: Apical membrane antigen 1, New antigen receptor variable domain
著者Streltsov, V.A, Henderson, K.A, Batchelor, A.H, Coley, A.M, Nuttall, S.D.
登録日2007-09-11
公開日2007-11-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of an IgNAR-AMA1 Complex: Targeting a Conserved Hydrophobic Cleft Broadens Malarial Strain Recognition
Structure, 15, 2007
2K9Y
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BU of 2k9y by Molmil
EphA2 dimeric structure in the lipidic bicelle at pH 5.0
分子名称: Ephrin type-A receptor 2
著者Mayzel, M.L, Bocharov, E.V, Volynsky, P.E, Arseniev, A.S.
登録日2008-10-27
公開日2009-08-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Left-Handed Dimer of EphA2 Transmembrane Domain: Helix Packing Diversity among Receptor Tyrosine Kinases
Biophys.J., 98, 2010
2KAX
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BU of 2kax by Molmil
Solution structure and dynamics of S100A5 in the apo and Ca2+ -bound states
分子名称: Protein S100-A5
著者Bertini, I, Das Gupta, S, Hu, X, Karavelas, T, Luchinat, C, Parigi, G, Yuan, J, Structural Proteomics in Europe (SPINE), Structural Proteomics in Europe 2 (SPINE-2)
登録日2008-11-17
公開日2009-06-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of S100A5 in the apo and Ca2+-bound states
J.Biol.Inorg.Chem., 14, 2009
3EPA
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BU of 3epa by Molmil
Human AdoMetDC E178Q mutant complexed with putrescine
分子名称: 1,4-DIAMINOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYRUVIC ACID, ...
著者Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008
2ZDM
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BU of 2zdm by Molmil
Exploring trypsin S3 pocket
分子名称: (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ...
著者Baum, B, Brandt, T, Heine, A, Klebe, G.
登録日2007-11-26
公開日2008-10-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
2KFM
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Mouse Prion Protein (121-231) with Mutations Y225A and Y226A
分子名称: Major prion protein
著者Christen, B, Hornemann, S, Damberger, F.F, Wuthrich, K.
登録日2009-02-24
公開日2009-06-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Prion Protein NMR Structure from Tammar Wallaby (Macropus eugenii) Shows that the beta2-alpha2 Loop Is Modulated by Long-Range Sequence Effects.
J.Mol.Biol., 389, 2009
2ZG2
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BU of 2zg2 by Molmil
Crystal Structure of Two N-terminal Domains of Native Siglec-5
分子名称: Sialic acid-binding Ig-like lectin 5
著者Zhuravleva, M.A, Sun, P.D.
登録日2008-01-17
公開日2008-02-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
2ZGH
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Crystal Structure of active granzyme M bound to its product
分子名称: Granzyme M, SSGKVPL, SULFATE ION
著者Wu, L.F, Wang, L, Hua, G.Q, Liu, K, Zhai, Y.J, Sun, F, Fan, Z.S.
登録日2008-01-22
公開日2009-01-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M
J.Immunol., 183, 2009

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