1CUH
| CUTINASE, R196E MUTANT | 分子名称: | CUTINASE | 著者 | Longhi, S, Cambillau, C. | 登録日 | 1995-11-16 | 公開日 | 1996-07-11 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants. Proteins, 26, 1996
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1CUF
| CUTINASE, R156L MUTANT | 分子名称: | CUTINASE | 著者 | Longhi, S, Cambillau, C. | 登録日 | 1995-11-16 | 公開日 | 1996-07-11 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants. Proteins, 26, 1996
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2Y5F
| FACTOR XA - CATION INHIBITOR COMPLEX | 分子名称: | (3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,2-OXAZOL-3-YL]-2-[3-[1-(2-HYDROXYETHYL)PYRROLIDIN-1-IUM-1-YL]PROPYL]-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZINE-1,3-DIONE, ACTIVATED FACTOR XA HEAVY CHAIN, FACTOR X LIGHT CHAIN, ... | 著者 | Banner, D.W, Salonen, L.M, Holland, M.C, Haap, W, Benz, J, Diederich, F. | 登録日 | 2011-01-13 | 公開日 | 2011-12-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Molecular Recognition at the Active Site of Factor Xa: Cation-Pi Interactions, Stacking on Planar Peptide Surfaces, and Replacement of Structural Water. Chemistry, 18, 2012
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3HRH
| Crystal Structure of Antigen 85C and Glycerol | 分子名称: | Antigen 85-C, GLYCEROL | 著者 | Boucau, J, Sanki, A.K, Umesiri, F.E, Sucheck, S.J, Ronning, D.R. | 登録日 | 2009-06-09 | 公開日 | 2009-09-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design, synthesis and biological evaluation of sugar-derived esters, alpha-ketoesters and alpha-ketoamides as inhibitors for Mycobacterium tuberculosis antigen 85C. Mol Biosyst, 5, 2009
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3I2Y
| Proteinase K by Classical hanging drop Method before high X-Ray dose on ID14-2 Beamline at ESRF | 分子名称: | CALCIUM ION, Proteinase K | 著者 | Pechkova, E, Tripathi, S.K, Ravelli, R, McSweeney, S, Nicolini, C. | 登録日 | 2009-06-30 | 公開日 | 2010-06-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (0.995 Å) | 主引用文献 | Atomic structure and radiation resistance of Langmuir-Blodgett protein crystals To be Published
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2XBJ
| Crystal Structure of Chk2 in complex with an inhibitor | 分子名称: | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, NITRATE ION, ... | 著者 | Anderson, V.E, Walton, M.I, Eve, P.D, Caldwell, J.J, Pearl, L.H, Oliver, A.W, Collins, I, Garrett, M.D. | 登録日 | 2010-04-12 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2. J.Med.Chem., 54, 2011
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3HYQ
| Crystal Structure of Isopentenyl-Diphosphate delta-Isomerase from Salmonella entericase | 分子名称: | Isopentenyl-diphosphate Delta-isomerase | 著者 | Kim, Y, Zhou, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-06-22 | 公開日 | 2009-06-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.525 Å) | 主引用文献 | Crystal Structure of Isopentenyl-Diphosphate delta-Isomerase from Salmonella entericase To be Published
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3I30
| Proteinase K by Classical hanging drop Method after high X-Ray dose on ID14-2 Beamline at ESRF | 分子名称: | CALCIUM ION, Proteinase K | 著者 | Pechkova, E, Tripathi, S.K, Ravelli, R, McSweeney, S, Nicolini, C. | 登録日 | 2009-06-30 | 公開日 | 2010-06-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (0.992 Å) | 主引用文献 | Atomic structure and radiation resistance of Langmuir-Blodgett protein crystals To be Published
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2XBS
| Raman crystallography of Hen White Egg Lysozyme - High X-ray dose (16 MGy) | 分子名称: | CHLORIDE ION, LYSOZYME C | 著者 | Carpentier, P, Royant, A, Weik, M, Bourgeois, D. | 登録日 | 2010-04-14 | 公開日 | 2010-11-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Raman Assisted Crystallography Reveals a Mechanism of X-Ray Induced Reversible Disulfide Radical Formation Structure, 18, 2010
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2XM9
| Structure of a small molecule inhibitor with the kinase domain of Chk2 | 分子名称: | 4-(1H-pyrazol-5-yl)-2-{4-[(3S)-pyrrolidin-3-ylamino]quinazolin-2-yl}phenol, NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 | 著者 | Caldwell, J.J, Welsh, E.J, Matijssen, C, Anderson, V.E, Antoni, L, Boxall, K, Urban, F, Hayes, A, Raynaud, F.I, Rigoreau, L.J, Raynham, T, Aherne, G.W, Pearl, L.H, Oliver, A.W, Garrett, M.D, Collins, I. | 登録日 | 2010-07-26 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2. J.Med.Chem., 54, 2011
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3I06
| Crystal structure of cruzain covalently bound to a purine nitrile | 分子名称: | 6-[(3,5-difluorophenyl)amino]-9-ethyl-9H-purine-2-carbonitrile, Cruzipain | 著者 | Ferreira, R.S, Shoichet, B.K, McKerrow, J.H. | 登録日 | 2009-06-24 | 公開日 | 2009-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Identification and optimization of inhibitors of trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB. J.Med.Chem., 53, 2010
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3HW1
| Structure of Bace (beta secretase) in complex with ligand EV2 | 分子名称: | 3-pyrrolidin-1-ylquinoxalin-2-amine, Beta-secretase 1, GLYCEROL | 著者 | Godemann, R, Madden, J, Kramer, J, Smith, M.A, Barker, J, Ebneth, A. | 登録日 | 2009-06-17 | 公開日 | 2009-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays Biochemistry, 48, 2009
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2XM8
| Co-crystal structure of a small molecule inhibitor bound to the kinase domain of Chk2 | 分子名称: | 2-{4-[(3S)-PYRROLIDIN-3-YLAMINO]QUINAZOLIN-2-YL}PHENOL, SERINE/THREONINE-PROTEIN KINASE CHK2 | 著者 | Caldwell, J.J, Welsh, E.J, Matijssen, C, Anderson, V.E, Antoni, L, Boxall, K, Urban, F, Hayes, A, Raynaud, F.I, Rigoreau, L.J, Raynham, T, Aherne, G.W, Pearl, L.H, Oliver, A.W, Garrett, M.D, Collins, I. | 登録日 | 2010-07-26 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2. J.Med.Chem., 54, 2011
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3L1F
| Bovine AlphaA crystallin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin A chain | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2009-12-11 | 公開日 | 2010-05-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci., 19, 2010
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2UZS
| A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K) | 分子名称: | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-alpha serine/threonine-protein kinase | 著者 | Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E. | 登録日 | 2007-05-01 | 公開日 | 2007-07-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature, 448, 2007
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3KWV
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1BZ5
| EVIDENCE OF A COMMON DECAMER IN THREE CRYSTAL STRUCTURES OF BPTI, CRYSTALLIZE FROM THIOCYANATE, CHLORIDE OR SULFATE | 分子名称: | PANCREATIC TRYPSIN INHIBITOR, SULFATE ION | 著者 | Hamiaux, C, Prange, T, Ries-Kautt, M, Ducruix, A, Lafont, S, Astier, J.P, Veesler, S. | 登録日 | 1998-11-05 | 公開日 | 1998-11-11 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | The BPTI decamer observed in acidic pH crystal forms pre-exists as a stable species in solution. J.Mol.Biol., 297, 2000
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2VIY
| Human BACE-1 in complex with N-((1S,2R)-3-(((1S)-2-(cyclohexylamino)- 1-methyl-2-oxoethyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-3-(pentylsulfonyl)benzamide | 分子名称: | BETA-SECRETASE 1, N-[(1S,2R)-1-benzyl-3-{[(1S)-2-(cyclohexylamino)-1-methyl-2-oxoethyl]amino}-2-hydroxypropyl]-3-(pentylsulfonyl)benzamide | 著者 | Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Faller, A, Hawkins, J, Hussain, I, MacPherson, D, Maile, G, Matico, R, Milner, P, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Riddell, D, Rowland, P, Soleil, V, Smith, K, Stanway, S, Stemp, G, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Ward, J, Wayne, G. | 登録日 | 2007-12-06 | 公開日 | 2008-01-29 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Bace-1 Inhibitors Part 1: Identification of Novel Hydroxy Ethylamines (Heas). Bioorg.Med.Chem.Lett., 18, 2008
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2V36
| Crystal structure of gamma-glutamyl transferase from Bacillus subtilis | 分子名称: | GAMMA-GLUTAMYLTRANSPEPTIDASE LARGE CHAIN, GAMMA-GLUTAMYLTRANSPEPTIDASE SMALL CHAIN | 著者 | Sharath, B, Prabhune, A.A, Suresh, C.G, Wilkinson, A.J, Brannigan, J.A. | 登録日 | 2007-06-13 | 公開日 | 2008-07-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of Gamma-Glutamyl Transferase To be Published
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3HYE
| Crystal structure of 20S proteasome in complex with hydroxylated salinosporamide | 分子名称: | (2R,3S,4R)-2-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-3-hydroxy-4-(2-hydroxyethyl)-3-methyl-5-oxopyrrolidine-2-carbaldehyde, Proteasome component C1, Proteasome component C11, ... | 著者 | Groll, M, Arthur, K.A.M, Macherla, V.R, Manam, R.R, Potts, B.C. | 登録日 | 2009-06-22 | 公開日 | 2009-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition J.Med.Chem., 52, 2009
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2V8B
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3I34
| Proteinase K by LB Nanotemplate Method after high X-Ray dose on ID14-2 Beamline at ESRF | 分子名称: | CALCIUM ION, MERCURY (II) ION, Proteinase K | 著者 | Pechkova, E, Tripathi, S.K, Ravelli, R, McSweeney, S, Nicolini, C. | 登録日 | 2009-06-30 | 公開日 | 2010-06-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Radiation damage study of Proteinase K at ID14-2 beamline at ESRF To be Published
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3HVG
| Structure of bace (beta secretase) in Complex with EV0 | 分子名称: | 2-amino-6-propylpyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL | 著者 | Godemann, R, Madden, J, Kramer, J, Smith, M.A, Barker, J, Ebneth, A. | 登録日 | 2009-06-16 | 公開日 | 2009-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays Biochemistry, 48, 2009
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2VKM
| Crystal structure of GRL-8234 bound to BACE (Beta-secretase) | 分子名称: | BETA-SECRETASE 1, N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | 著者 | Hong, L, Tang, J, Ghosh, A.K. | 登録日 | 2007-12-04 | 公開日 | 2008-12-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Potent Memapsin 2 (Beta-Secretase) Inhibitors: Design, Synthesis, Protein-Ligand X-Ray Structure, and in Vivo Evaluation. Bioorg.Med.Chem.Lett., 18, 2008
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3HLN
| Crystal structure of ClpP A153C mutant with inter-heptamer disulfide bonds | 分子名称: | ATP-dependent Clp protease proteolytic subunit, CALCIUM ION | 著者 | Kimber, M.S, Yu, A.Y.H, Borg, M, Chan, H.S, Houry, W.A. | 登録日 | 2009-05-27 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and Theoretical Studies Indicate that the Cylindrical Protease ClpP Samples Extended and Compact Conformations. Structure, 18, 2010
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