5QMN
| |
5QN2
| |
5QNH
| |
5QNZ
| |
5QOE
| |
1Y6A
| Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor | 分子名称: | N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE, Vascular endothelial growth factor receptor 2 | 著者 | Harris, P.A, Cheung, M, Hunter, R.N, Brown, M.L, Veal, J.M, Nolte, R.T, Wang, L, Liu, W, Crosby, R.M, Johnson, J.H, Epperly, A.H, Kumar, R, Luttrell, D.K, Stafford, J.A. | 登録日 | 2004-12-05 | 公開日 | 2005-06-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors. J.Med.Chem., 48, 2005
|
|
5QL2
| |
5QLL
| |
5QM2
| |
6AK2
| Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018 | 分子名称: | Syntenin-1, peptide inhibitor KSL-128018 | 著者 | Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T. | 登録日 | 2018-08-29 | 公開日 | 2019-09-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.868 Å) | 主引用文献 | A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. J.Med.Chem., 64, 2021
|
|
3SRV
| Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine carboxamide inhibitor | 分子名称: | 2-{[(3R,4R)-3-aminotetrahydro-2H-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide, GLYCEROL, Tyrosine-protein kinase SYK | 著者 | Somers, D.O, Neu, M. | 登録日 | 2011-07-07 | 公開日 | 2011-09-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor. Bioorg.Med.Chem.Lett., 21, 2011
|
|
5QMQ
| |
5QNA
| |
5QNP
| |
5QO8
| |
5QKD
| |
5QKR
| |
5QL7
| |
5QLO
| |
5QM6
| |
5QML
| |
4DBS
| Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) in complex with NADP+ and 3'-[(4-nitronaphthalen-1-yl)amino]benzoic acid | 分子名称: | 3-[(4-nitronaphthalen-1-yl)amino]benzoic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Chen, M, Christianson, D.W, Winkler, J.D, Penning, T.M. | 登録日 | 2012-01-16 | 公開日 | 2012-03-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | 主引用文献 | Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer. Bioorg.Med.Chem.Lett., 22, 2012
|
|
5QN1
| |
5QNG
| |
5QNW
| |