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2XHM
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Crystal structure of AnCE-K26 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ...
著者Akif, M, Ntai, I, Sturrock, E.D, Isaac, R.E, Bachmann, B.O, Acharya, K.R.
登録日2010-06-18
公開日2010-07-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal Structure of a Phosphonotripeptide K-26 in Complex with Angiotensin Converting Enzyme Homologue (Ance) from Drosophila Melanogaster.
Biochem.Biophys.Res.Commun., 398, 2010
5D6T
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Crystal Structure of Aspergillus clavatus Sph3 in complex with GalNAc
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, CHLORIDE ION, SPHERULIN-4, ...
著者Bamford, N.C, Little, D.J, Howell, P.L.
登録日2015-08-12
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus.
J.Biol.Chem., 290, 2015
8X83
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The cryo-EM structure of insect gustatory receptor Gr43a I418A from Drosophila melanogaster in complex with fructose
分子名称: Gustatory receptor for sugar taste 43a, SODIUM ION, beta-D-fructofuranose
著者Ma, D, Guo, J.
登録日2023-11-27
公開日2024-02-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for sugar perception by Drosophila gustatory receptors.
Science, 383, 2024
4ZA5
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Structure of A. niger Fdc1 with the prenylated-flavin cofactor in the iminium and ketimine forms.
分子名称: 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, 1-deoxy-5-O-phosphono-1-[(10aR)-2,2,3,4-tetramethyl-8,10-dioxo-1,2,8,9,10,10a-hexahydro-6H-indeno[1,7-ef]pyrimido[4,5-b][1,4]diazepin-6-yl]-D-ribitol, Fdc1, ...
著者Payne, K.A.P, Leys, D.
登録日2015-04-13
公開日2015-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献New cofactor supports alpha , beta-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition.
Nature, 522, 2015
6F0B
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BU of 6f0b by Molmil
Cytochrome P450 TxtC employs substrate conformational switching for sequential aliphatic and aromatic thaxtomin hydroxylation
分子名称: (3~{S},6~{S})-1,4-dimethyl-3-[(4-nitro-1~{H}-indol-3-yl)methyl]-6-(phenylmethyl)piperazine-2,5-dione, Cytochrome P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Fulop, V.
登録日2017-11-17
公開日2018-12-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC.
J.Am.Chem.Soc., 141, 2019
8X84
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The cryo-EM structure of insect gustatory receptor Gr43a I418A from Drosophila melanogaster in complex with fructose and calcium
分子名称: CALCIUM ION, Gustatory receptor for sugar taste 43a, beta-D-fructofuranose
著者Ma, D, Guo, J.
登録日2023-11-27
公開日2024-02-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for sugar perception by Drosophila gustatory receptors.
Science, 383, 2024
7CYV
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Crystal structure of FD20, a neutralizing single-chain variable fragment (scFv) in complex with SARS-CoV-2 Spike receptor-binding domain (RBD)
分子名称: Spike protein S1, The heavy chain variable region of the scFv FD20,The light chain variable region of the scFv FD20, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Li, Y, Li, T, Lai, Y, Cai, H, Yao, H, Li, D.
登録日2020-09-04
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody.
Embo Mol Med, 13, 2021
8R2H
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Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Plasmodium falciparum
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
著者Gawriljuk, V.O, Godoy, A.S, Oerlemans, R, Groves, M.R.
登録日2023-11-06
公開日2024-06-12
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain.
Nat Commun, 15, 2024
5F96
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Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.12 in complex with HIV-1 clade A/E 93TH057 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY CH235.12, ...
著者Zhou, T, Kwong, P.D.
登録日2015-12-09
公開日2016-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2407 Å)
主引用文献Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
6B3P
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BU of 6b3p by Molmil
Crystal structure of CBMbc (family CBM26) from Eubacterium rectale Amy13K in Complex with Maltoheptaose
分子名称: 1,2-ETHANEDIOL, Amy13K, FORMIC ACID, ...
著者Cockburn, D.W, Wawrzak, Z, Perez Medina, K, Koropatkin, N.M.
登録日2017-09-22
公開日2017-11-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Novel carbohydrate binding modules in the surface anchored alpha-amylase of Eubacterium rectale provide a molecular rationale for the range of starches used by this organism in the human gut.
Mol. Microbiol., 107, 2018
6SWR
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BU of 6swr by Molmil
Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc
分子名称: DODECYL-BETA-D-MALTOSIDE, Nanobody, Maltose/maltodextrin-binding periplasmic protein,Maltodextrin-binding protein,Maltose/maltodextrin-binding periplasmic protein, ...
著者Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S.
登録日2019-09-23
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for ion selectivity in TMEM175 K + channels.
Elife, 9, 2020
6GLD
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BU of 6gld by Molmil
Intercalation of [Ru(TAP)2(11-Br-dppz)]2+ bound to d(TCGGCGCCGA)2
分子名称: BARIUM ION, Ruthenium (bis-(tetraazaphenanthrene)) (11-bromo-dipyridophenazine), d(TCGGCGCCGA)2
著者McQuaid, K.T, Hall, J.P, Cardin, C.J.
登録日2018-05-23
公開日2019-06-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.061 Å)
主引用文献X-ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru-dppz Complexes.
Chemistry, 24, 2018
5FSG
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BU of 5fsg by Molmil
Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation and a template for drug design
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN, HANTAVIRUS NUCLEOPROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Olal, D, Daumke, O.
登録日2016-01-05
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.209 Å)
主引用文献Structure of the Hantavirus Nucleoprotein Provides Insights Into the Mechanism of RNA Encapsidation.
Cell Rep., 14, 2016
4RFN
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BU of 4rfn by Molmil
Crystal structure of ADCC-potent Rhesus macaque ANTIBODY JR4 in complex with HIV-1 CLADE A/E GP120 and M48
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, FAB LIGHT CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, ...
著者Gohain, N, Tolbert, W.D, Pazgier, M.
登録日2014-09-26
公開日2015-07-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1.
J.Virol., 89, 2015
8D6K
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BU of 8d6k by Molmil
Sco GlgEI-V279S in complex with cyclohexyl carbasugar
分子名称: (1R,4S,5S,6R)-4-(cyclohexylamino)-5,6-dihydroxy-2-(hydroxymethyl)cyclohex-2-en-1-yl alpha-D-glucopyranoside, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, DI(HYDROXYETHYL)ETHER
著者Jayasinghe, T.J, Ronning, D.R.
登録日2022-06-06
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Synthesis of C 7 /C 8 -cyclitols and C 7 N-aminocyclitols from maltose and X-ray crystal structure of Streptomyces coelicolor GlgEI V279S in a complex with an amylostatin GXG-like derivative.
Front Chem, 10, 2022
2X8Y
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Crystal structure of AnCE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN CONVERTING ENZYME, CITRATE ANION, ...
著者Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R.
登録日2010-03-14
公開日2010-06-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.
J.Mol.Biol., 400, 2010
2WR0
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BU of 2wr0 by Molmil
Structures of influenza H2 Hemagglutinins
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, ...
著者Liu, J, Stevens, D, Haire, L, Coombs, P, Russell, R, Gamblin, S, Skehel, J.
登録日2009-08-28
公開日2009-09-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
4RHN
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HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT COMPLEXED WITH ADENOSINE
分子名称: HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN, alpha-D-ribofuranose
著者Brenner, C, Garrison, P, Gilmour, J, Peisach, D, Ringe, D, Petsko, G.A, Lowenstein, J.M.
登録日1997-02-26
公開日1997-06-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins.
Nat.Struct.Biol., 4, 1997
4Y7P
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BU of 4y7p by Molmil
Structure of alkaline D-peptidase from Bacillus cereus
分子名称: Alkaline D-peptidase, THIOCYANATE ION
著者Nakano, S, Okazaki, S, Ishitsubo, E, Kawahara, N, Komeda, H, Tokiwa, H, Asano, Y.
登録日2015-02-15
公開日2015-10-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and computational analysis of peptide recognition mechanism of class-C type penicillin binding protein, alkaline D-peptidase from Bacillus cereus DF4-B
Sci Rep, 5, 2015
7LS0
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Structure of the Human ALK GRD bound to AUG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID
著者Stayrook, S, Li, T, Klein, D.E.
登録日2021-02-17
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LI9
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5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
著者Yang, D, Gouaux, E.
登録日2021-01-26
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LIA
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5-HT bound serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in outward facing conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL, ...
著者Yang, D, Gouaux, E.
登録日2021-01-26
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI8
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apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in inward open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, DODECANE, ...
著者Yang, D, Gouaux, E.
登録日2021-01-26
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
5DFM
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Structure of Tetrahymena telomerase p19 fused to MBP
分子名称: GLYCEROL, Maltose-binding periplasmic protein,Telomerase-associated protein 19, SULFATE ION, ...
著者Chan, H, Cascio, D, Sawaya, M.R, Feigon, J.
登録日2015-08-27
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015
7MPG
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Cryo-EM structure of Prefusion-stabilized RSV F (DS-Cav1) in complex with Fab AM14
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AM14 Fab Heavy Chain, AM14 Fab Light Chain, ...
著者Abeyrathne, P.D, Malito, E, Harshbarger, W.D.
登録日2021-05-04
公開日2021-09-08
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein.
Mabs, 13

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