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8YRT
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Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis in the holo form obtained at pH 7.0
分子名称: Aminotransferase class IV, PYRIDOXAL-5'-PHOSPHATE
著者Matyuta, I.O, Bakunova, A.K, Minyaev, M.E, Popov, V.O, Boyko, K.M.
登録日2024-03-21
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis in the holo form obtained at pH 7.0
To Be Published
8DL5
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Crystal structure of PLP-dependent Mannich cyclase LolT
分子名称: Aminotransferase, class V/Cysteine desulfurase, GLYCEROL
著者Gao, J, Hai, Y.
登録日2022-07-06
公開日2023-06-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A pyridoxal 5'-phosphate-dependent Mannich cyclase.
Nat Catal, 2023
7VMY
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Crystal structure of LimF prenyltransferase bound with GSPP
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GERANYL S-THIOLODIPHOSPHATE, LynF/TruF/PatF family peptide O-prenyltransferase, ...
著者Hamada, K, Kobayashi, S, Okada, C, Zhang, Y, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
登録日2021-10-09
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
Nat Catal, 2022
7VMW
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Crystal structure of LimF prenyltransferase bound with a peptide substrate and GSPP
分子名称: GERANYL S-THIOLODIPHOSPHATE, LynF/TruF/PatF family peptide O-prenyltransferase, MAGNESIUM ION, ...
著者Hamada, K, Kobayashi, S, Okada, C, Zhang, Y, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
登録日2021-10-09
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
Nat Catal, 2022
4GPA
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High resolution structure of the GluA4 N-terminal domain (NTD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 4
著者Sukumaran, M, Greger, I.H.
登録日2012-08-20
公開日2012-10-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Comparative Dynamics of NMDA- and AMPA-Glutamate Receptor N-Terminal Domains.
Structure, 20, 2012
8JE4
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Crystal structure of LimF prenyltransferase (H239G/W273T mutant) bound with the thiodiphosphate moiety of farnesyl S-thiolodiphosphate (FSPP)
分子名称: MAGNESIUM ION, TRIHYDROGEN THIODIPHOSPHATE, prenyltransferase, ...
著者Hamada, K, Oguni, A, Zhang, Y, Satake, M, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
登録日2023-05-15
公開日2023-11-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Switching Prenyl Donor Specificities of Cyanobactin Prenyltransferases.
J.Am.Chem.Soc., 145, 2023
8KDL
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Crystal structure of LmbF in complex with PLP
分子名称: Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme, GLYCEROL
著者Mori, T, Lyu, S, Kadlcik, S, Abe, I.
登録日2023-08-09
公開日2024-08-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of LmbF in complex with PLP
To Be Published
8Q3V
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Cryo-EM structure of the methanogenic Na+ translocating N5-methyl-H4MPT:CoM methyltransferase complex
分子名称: MAGNESIUM ION, SODIUM ION, Tetrahydromethanopterin S-methyltransferase subunit A 1, ...
著者Aziz, I, Vonck, J, Ermler, U.
登録日2023-08-04
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.08 Å)
主引用文献Structural and mechanistic basis of the central energy-converting methyltransferase complex of methanogenesis.
Proc.Natl.Acad.Sci.USA, 121, 2024
8Q54
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N5-methyl-H4MPT:CoM methyltransferase -coenzyme M complex + CoM
分子名称: 1-THIOETHANESULFONIC ACID, MAGNESIUM ION, SODIUM ION, ...
著者Aziz, I, Vonck, J, Ermler, U.
登録日2023-08-08
公開日2024-08-21
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Cryo-EM structure of the methanogenic Na+ translocating N5-methyl-H4MPT:CoM methyltransferase complex
To Be Published
2CMO
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The structure of a mixed glur2 ligand-binding core dimer in complex with (s)-glutamate and the antagonist (s)-ns1209
分子名称: 2-({[(3E)-5-{4-[(DIMETHYLAMINO)(DIHYDROXY)-LAMBDA~4~-SULFANYL]PHENYL}-8-METHYL-2-OXO-6,7,8,9-TETRAHYDRO-1H-PYRROLO[3,2-H]ISOQUINOLIN-3(2H)-YLIDENE]AMINO}OXY)-4-HYDROXYBUTANOIC ACID, GLUTAMATE RECEPTOR 2, GLUTAMIC ACID, ...
著者Kasper, C, Pickering, D.S, Mirza, O, Olsen, L, Kristensen, A.S, Greenwood, J.R, Liljefors, T, Schousboe, A, Watjen, F, Gajhede, M, Sigurskjold, B.W, Kastrup, J.S.
登録日2006-05-11
公開日2006-06-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The Structure of a Mixed Glur2 Ligand-Binding Core Dimer in Complex with (S)-Glutamate and the Antagonist (S)-Ns1209.
J.Mol.Biol., 357, 2006
1N0T
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X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution.
分子名称: (S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID, ACETATE ION, Glutamate receptor 2, ...
著者Hogner, A, Greenwood, J.R, Liljefors, T, Lunn, M.-L, Egebjerg, J, Larsen, I.K, Gouaux, E, Kastrup, J.S.
登録日2002-10-15
公開日2003-03-04
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX.
J.Med.Chem., 46, 2003
1XHY
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X-ray structure of the Y702F mutant of the GluR2 ligand-binding core (S1S2J) in complex with kainate at 1.85 A resolution
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor, SULFATE ION
著者Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S.
登録日2004-09-21
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.
Mol.Pharmacol., 67, 2005
8TKP
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Structure of the C. elegans TMC-2 complex
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Clark, S, Jeong, H, Goehring, A, Posert, R, Gouaux, E.
登録日2023-07-25
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction.
Proc.Natl.Acad.Sci.USA, 121, 2024
1JBM
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Heptameric crystal structure of Mth649, an Sm-like archaeal protein from Methanobacterium thermautotrophicum
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, PUTATIVE SNRNP SM-LIKE PROTEIN
著者Mura, C, Eisenberg, D.
登録日2001-06-06
公開日2003-03-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
1HBM
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METHYL-COENZYME M REDUCTASE ENZYME PRODUCT COMPLEX
分子名称: CHLORIDE ION, FACTOR 430, GLYCEROL, ...
著者Ermler, U, Grabarse, W.
登録日2001-04-20
公開日2001-08-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献On the Mechanism of Biological Methane Formation: Structural Evidence for Conformational Changes in Methyl-Coenzyme M Reductase Upon Substrate Binding
J.Mol.Biol., 309, 2001
1HBU
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METHYL-COENZYME M REDUCTASE IN THE MCR-RED1-SILENT STATE IN COMPLEX with COENZYME M
分子名称: 1-THIOETHANESULFONIC ACID, CHLORIDE ION, Coenzyme B, ...
著者Ermler, U, Grabarse, W.
登録日2001-04-20
公開日2001-08-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献On the Mechanism of Biological Methane Formation: Structural Evidence for Conformational Changes in Methyl-Coenzyme M Reductase Upon Substrate Binding
J.Mol.Biol., 309, 2001
1HBO
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METHYL-COENZYME M REDUCTASE MCR-RED1-SILENT
分子名称: 1-THIOETHANESULFONIC ACID, CHLORIDE ION, Coenzyme B, ...
著者Grabarse, W.
登録日2001-04-20
公開日2001-08-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献On the Mechanism of Biological Methane Formation: Structural Evidence for Conformational Changes in Methyl-Coenzyme M Reductase Upon Substrate Binding
J.Mol.Biol., 309, 2001
1HBN
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METHYL-COENZYME M REDUCTASE
分子名称: 1-THIOETHANESULFONIC ACID, CHLORIDE ION, Coenzyme B, ...
著者Ermler, U, Grabarse, W.
登録日2001-04-20
公開日2001-08-16
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献On the Mechanism of Biological Methane Formation: Structural Evidence for Conformational Changes in Methyl-Coenzyme M Reductase Upon Substrate Binding
J.Mol.Biol., 309, 2001
1SYH
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X-RAY STRUCTURE OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 1.85 A RESOLUTION.
分子名称: (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID, Glutamate receptor 2
著者Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S.
登録日2004-04-01
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.
Mol.Pharmacol., 67, 2005
1SYI
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X-RAY STRUCTURE OF THE Y702F MUTANT OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 2.1 A RESOLUTION.
分子名称: (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID, Glutamate receptor 2
著者Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S.
登録日2004-04-01
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.
Mol.Pharmacol., 67, 2005
2KKE
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Solution NMR Structure of a dimeric protein of unknown function from Methanobacterium thermoautotrophicum, Northeast Structural Genomics Consortium Target TR5
分子名称: Uncharacterized protein
著者Swapna, G.V.T, Gunsalus, X, Huang, L, Xiao, K, Everett, J.K, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2009-06-18
公開日2009-07-14
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of a putative uncharacterized protein from Methanobacterium thermoautotrophicum, Northeast Structural Genomics Consortium Target:TR5
To be Published
1NHO
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Structural and Functional characterization of a Thioredoxin-like Protein from Methanobacterium thermoautotrophicum
分子名称: Probable Thioredoxin
著者Amegbey, G.Y, Monzavi, H, Habibi-Nazhad, B, Bhattacharyya, S, Wishart, D.S.
登録日2002-12-19
公開日2003-08-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and Functional Characterization of a Thioredoxin-like Protein (Mt0807) from Methanobacterium thermoautotrophicum
Biochemistry, 42, 2003
5IPU
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Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 6
分子名称: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
著者Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
登録日2016-03-09
公開日2016-04-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (15.4 Å)
主引用文献Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPT
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Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 5
分子名称: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
著者Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
登録日2016-03-09
公開日2016-04-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (14.1 Å)
主引用文献Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPS
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Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 4
分子名称: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
著者Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
登録日2016-03-09
公開日2016-04-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016

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