PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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4TKD	Sulfolobus solfataricus HJC mutants 分子名称: Holliday junction resolvase Hjc 著者 Bond, C.S. 登録日 2014-05-26 公開日 2015-08-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal Unengineering: Reducing the Crystallisability of Sulfolobus solfataricus Hjc Aust.J.Chem., 67, 2014
4TKK	Sulfolobus solfataricus HJC mutants 分子名称: Holliday junction resolvase Hjc 著者 Bond, C.S. 登録日 2014-05-27 公開日 2015-08-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Unengineering: Reducing the Crystallisability of Sulfolobus solfataricus Hjc Aust.J.Chem., 67, 2014
5YYU	Crystal structure of Staphylococcus aureus single-stranded DNA-binding protein SsbB 分子名称: Single-stranded DNA-binding protein 著者 Huang, Y.H, Huang, C.Y. 登録日 2017-12-11 公開日 2018-08-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.984 Å) 主引用文献 Characterization of single-stranded DNA-binding protein SsbB from Staphylococcus aureus: SsbB cannot stimulate PriA helicase. Rsc Adv, 8, 2018
4RQL	Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with a monoterpene - sabinene 分子名称: 1,2-ETHANEDIOL, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... 著者 Shah, M.B. 登録日 2014-11-03 公開日 2015-01-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison. Mol.Pharmacol., 87, 2015
4TL8	Crystal structure of N-terminal C1 domain of KaiC 分子名称: CHLORIDE ION, Circadian clock protein kinase KaiC, MAGNESIUM ION, ... 著者 Abe, J, Hiyama, T.B, Mukaiyama, A, Son, S, Akiyama, S. 登録日 2014-05-29 公開日 2015-07-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.859 Å) 主引用文献 Atomic-scale origins of slowness in the cyanobacterial circadian clock Science, 349, 2015
2CA2	CRYSTALLOGRAPHIC STUDIES OF INHIBITOR BINDING SITES IN HUMAN CARBONIC ANHYDRASE II. A PENTACOORDINATED BINDING OF THE SCN-ION TO THE ZINC AT HIGH P*H 分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, THIOCYANATE ION, ... 著者 Eriksson, A.E, Kylsten, P.M, Jones, T.A, Liljas, A. 登録日 1989-02-06 公開日 1990-01-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic studies of inhibitor binding sites in human carbonic anhydrase II: a pentacoordinated binding of the SCN- ion to the zinc at high pH. Proteins, 4, 1988
5B3J	Activation of NMDA receptors and the mechanism of inhibition by ifenprodil 分子名称: Fab, heavy chain, light chain, ... 著者 Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. 登録日 2016-03-01 公開日 2016-05-11 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Activation of NMDA receptors and the mechanism of inhibition by ifenprodil Nature, 534, 2016
5HCV	Identification of Spirooxindole and Dibenzoxazepine Motifs as Potent Mineralocorticoid Receptor Antagonists 分子名称: 6-[(~{E})-(3-fluoranyl-6~{H}-benzo[c][1]benzoxepin-11-ylidene)methyl]-4~{H}-1,4-benzoxazin-3-one, CHLORIDE ION, Mineralocorticoid receptor 著者 Chen, G, McKeever, B.M. 登録日 2016-01-04 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists. Bioorg.Med.Chem., 24, 2016
6BKD	Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3D 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3D heavy chain, Fab AR3D light chain, ... 著者 Tzarum, N, Wilson, I.A, Law, M. 登録日 2017-11-08 公開日 2018-12-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies. Sci Adv, 5, 2019
5EDW	Ternary structure of Dpo4 bound to G in the template base paired with incoming dTTP 分子名称: CALCIUM ION, DNA (5'-D(*CP*TP*AP*AP*CP*GP*GP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2015-10-22 公開日 2016-11-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structure of Dpo4 DNA polymerase replicating across the genotoxic N7-methylguanine lesion To Be Published
4RUI	Crystal structure of a cytochrome P450 2A6 in complex with a monoterpene - sabinene. 分子名称: Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, Sabinene 著者 Shah, M.B, Stout, C.D, Halpert, J.R. 登録日 2014-11-19 公開日 2015-01-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison. Mol.Pharmacol., 87, 2015
5EJV	RORy in complex with T090131718 and Coactivator peptide EBI96 分子名称: EBI96 Coactivator Peptide, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, Nuclear receptor ROR-gamma 著者 Marcotte, D.M. 登録日 2015-11-02 公開日 2016-04-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Discovery of biaryls as ROR gamma inverse agonists by using structure-based design. Bioorg.Med.Chem.Lett., 26, 2016
5F9K	Dictyostelium discoideum dUTPase at 2.2 Angstrom 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, ... 著者 Inoguchi, N, Chia, C.P, Heck, K, Moriyama, H. 登録日 2015-12-09 公開日 2016-12-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.179 Å) 主引用文献 Mitochondrial localization of Dictyostelium discoideum dUTPase mediated by its N-terminus. Bmc Res Notes, 13, 2020
5ZNE	The crystal structure of immune receptor RGA5A_S of resistance protein Pia from rice (Oryza sativa) 分子名称: NBS-LRR type protein 著者 Guo, L.W, Huang, D, Liu, J.F, Peng, Y.L. 登録日 2018-04-09 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8I67	Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 2,4-Thiazolidinedione, Form I 分子名称: 1,2-ETHANEDIOL, 1,3-thiazolidine-2,4-dione, Uracil-DNA glycosylase 著者 Raj, P, Paul, A, Gopal, B. 登録日 2023-01-27 公開日 2023-07-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
8I61	Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid and Citric acid, Form I 分子名称: 1,2-ETHANEDIOL, BARBITURIC ACID, CITRIC ACID, ... 著者 Raj, P, Paul, A, Gopal, B. 登録日 2023-01-27 公開日 2023-07-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
8I69	Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 5-Fluoroorotic acid and Citric acid, Form I 分子名称: 1,2-ETHANEDIOL, 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CITRIC ACID, ... 著者 Raj, P, Paul, A, Gopal, B. 登録日 2023-01-27 公開日 2023-07-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
5ZNG	The crystal complex of immune receptor RGA5A_S of Pia from rice (Oryzae sativa) with rice blast (Magnaporthe oryzae) effector protein AVR1-CO39 分子名称: AVR1-CO39, NBS-LRR type protein 著者 Guo, L.W, Zhang, Y.K, Liu, Q, Ma, M.Q, Liu, J.F, Peng, Y.L. 登録日 2018-04-09 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.189 Å) 主引用文献 Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4TLD	Crystal structure of N-terminal C1 domain of KaiC 分子名称: CHLORIDE ION, Circadian clock protein kinase KaiC, MAGNESIUM ION, ... 著者 Abe, J, Hiyama, T.B, Mukaiyama, A, Son, S, Akiyama, S. 登録日 2014-05-29 公開日 2015-07-01 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.949 Å) 主引用文献 Atomic-scale origins of slowness in the cyanobacterial circadian clock Science, 349, 2015
6VBE	Crystal structure of recombinant mutant H180R of human fumarase 分子名称: Fumarate hydratase, mitochondrial, GLYCEROL, ... 著者 Ajalla, M.A.A, Nonato, M.C. 登録日 2019-12-18 公開日 2020-12-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 Crystal structure of recombinant mutant H180R of human fumarase To Be Published
5GGV	CTLA-4 in complex with tremelimumab Fab 分子名称: Cytotoxic T-lymphocyte protein 4, heavy chain, light chain 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2016-11-16 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
7N19	DR3 in complex with Aspergillus nidulans NAD-dependent histone deacetylase hst4 peptide 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wang, Y, Dai, S. 登録日 2021-05-27 公開日 2021-08-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope. J.Exp.Med., 218, 2021
7N6B	Structure of MmpL3 reconstituted into lipid nanodisc in the TMM bound state 分子名称: 6-O-[(2S)-2-{(1S)-18-[(1R,2R)-2-hexylcyclopropyl]-1-hydroxyoctadecyl}tricosanoyl]-alpha-D-glucopyranosyl alpha-D-glucopyranoside, MmpL3 transporter 著者 Su, C.C, Yu, E. 登録日 2021-06-08 公開日 2021-09-01 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. Plos Biol., 19, 2021
2FUM	Catalytic domain of protein kinase PknB from Mycobacterium tuberculosis in complex with mitoxantrone 分子名称: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, Probable serine/threonine-protein kinase pknB 著者 Wehenkel, A, Alzari, P.M. 登録日 2006-01-27 公開日 2006-08-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria Febs Lett., 580, 2006
8FWS	Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2023-01-23 公開日 2023-04-19 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023

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