PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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8DA8	Coevolved affibody-Z domain pair LL2.c1 分子名称: Affibody LL2.FIIK, GLYCEROL, Immunoglobulin G-binding protein A 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DA7	Coevolved affibody-Z domain pair LL1.c6 分子名称: Immunoglobulin G-binding protein A, MALONATE ION, affibody LL1.FIFV 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DAC	Coevolved affibody-Z domain pair LL2.c22 分子名称: Affibody LL2.FILV, GLYCEROL, Immunoglobulin G-binding protein A 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DAA	Coevolved affibody-Z domain pair LL2.c7 分子名称: Affibody LL2.FIVK, Immunoglobulin G-binding protein A, MALONATE ION 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DAB	Coevolved affibody-Z domain pair LL2.c17 分子名称: Affibody LL2.IVVY, Immunoglobulin G-binding protein A 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.134 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
5F3W	Structure of the ATPrS-Mre11/Rad50-DNA complex 分子名称: 27-MER DNA, DNA double-strand break repair Rad50 ATPase,DNA double-strand break repair Rad50 ATPase, DNA double-strand break repair protein Mre11, ... 著者 Liu, Y. 登録日 2015-12-03 公開日 2016-03-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex Embo J., 35, 2016
6UB3	Crystal structure of a GH128 (subgroup IV) endo-beta-1,3-glucanase from Lentinula edodes (LeGH128_IV) with laminaribiose at the surface-binding site 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, SULFATE ION, ... 著者 Santos, C.R, Lima, E.A, Mandelli, F, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
5C1B	p97-delta709-728 in complex with a UFD1-SHP peptide 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Haenzelmann, P, Schindelin, H. 登録日 2015-06-13 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions. Structure, 24, 2016
6UAV	Crystal structure of a GH128 (subgroup II) endo-beta-1,3-glucanase from Pseudomonas viridiflava (PvGH128_II) 分子名称: GLYCEROL, Glyco_hydro_cc domain-containing protein, SULFATE ION 著者 Santos, C.R, Costa, P.A.C.R, Lima, E.A, Mandelli, F, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
6UB1	Crystal structure of a GH128 (subgroup III) curdlan-specific exo-beta-1,3-glucanase from Blastomyces gilchristii (BgGH128_III) in complex with laminaribiose at -3 and -2 subsites 分子名称: GLYCOSIDE HYDROLASE, beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose 著者 Costa, P.A.C.R, Santos, C.R, Domingues, M.N, Lima, E.A, Mandelli, F, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
7FEH	Crystal structure of human DDR1 in complex with CH5541127 分子名称: Epithelial discoidin domain-containing receptor 1, N-[(5-chloranyl-2-ethylsulfonyl-phenyl)methyl]-3-piperazin-1-yl-5-(trifluoromethyloxy)benzamide, NITRATE ION 著者 Fukami, T.A, Kadono, S, Matsuura, T. 登録日 2021-07-20 公開日 2022-07-27 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Novel potent and highly selective DDR1 inhibitors from integrated lead finding Medicinal Chemistry Research, 32, 2023
4QIA	Crystal structure of human insulin degrading enzyme (ide) in complex with inhibitor N-benzyl-N-(carboxymethyl)glycyl-L-histidine 分子名称: Insulin-degrading enzyme, N-benzyl-N-(carboxymethyl)glycyl-L-histidine, ZINC ION 著者 Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J. 登録日 2014-05-30 公開日 2015-05-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.202 Å) 主引用文献 Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme. Eur.J.Med.Chem., 90, 2015
6UAR	Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase from Amycolatopsis mediterranei (AmGH128_I) in complex with laminaritriose 分子名称: Glyco_hydro_cc domain-containing protein, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose 著者 Costa, P.A.C.R, Santos, C.R, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
6UAU	Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase (E102A mutant) from Amycolatopsis mediterranei (AmGH128_I) in complex with laminaritriose and laminaribiose 分子名称: DI(HYDROXYETHYL)ETHER, Glyco_hydro_cc domain-containing protein, ZINC ION, ... 著者 Vieira, P.S, Cabral, L, Costa, P.A.C.R, Santos, C.R, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
6UB0	Crystal structure of a GH128 (subgroup III) curdlan-specific exo-beta-1,3-glucanase from Blastomyces gilchristii (BgGH128_III) in complex with laminaribiose at -2 and -1 subsites 分子名称: Glyco_hydro_cc domain-containing protein, beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose 著者 Costa, P.A.C.R, Santos, C.R, Domingues, M.N, Lima, E.A, Mandelli, F, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
6UBB	Crystal structure of a GH128 (subgroup VI) exo-beta-1,3-glucanase from Aureobasidium namibiae (AnGH128_VI) with laminaribiose at the surface-binding site 分子名称: Glyco_hydro_cc domain-containing protein, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose 著者 Santos, C.R, Vieira, P.S, Domingues, M.N, Cordeiro, R.L, Tomazini, A, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
7L7K	Cryo-EM structure of protein encoded by vaccine candidate BNT162b2 分子名称: Spike glycoprotein 著者 Lees, J.A, Han, S. 登録日 2020-12-28 公開日 2021-02-24 最終更新日 2021-04-21 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 BNT162b vaccines protect rhesus macaques from SARS-CoV-2. Nature, 592, 2021
6UB7	Crystal structure of a GH128 (subgroup V) exo-beta-1,3-glucanase from Cryptococcus neoformans (CnGH128_V) 分子名称: Glyco_hydro_cc domain-containing protein, POTASSIUM ION 著者 Santos, C.R, Costa, P.A.C.R, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
6UAT	Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase (E102A mutant) from Amycolatopsis mediterranei (AmGH128_I) in complex with laminaripentaose 分子名称: Glyco_hydro_cc domain-containing protein, ZINC ION, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose 著者 Vieira, P.S, Cabral, L, Costa, P.A.C.R, Santos, C.R, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
6UAY	Crystal structure of a GH128 (subgroup III) curdlan-specific exo-beta-1,3-glucanase from Blastomyces gilchristii (BgGH128_III) 分子名称: GLYCOSIDE HYDROLASE 著者 Costa, P.A.C.R, Santos, C.R, Domingues, M.N, Lima, E.A, Mandelli, F, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
6UB8	Crystal structure of a GH128 (subgroup VI) exo-beta-1,3-glucanase from Aureobasidium namibiae (AnGH128_VI) 分子名称: GLYCEROL, Glyco_hydro_cc domain-containing protein 著者 Santos, C.R, Vieira, P.S, Domingues, M.N, Cordeiro, R.L, Tomazini, A, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
5GGU	Crystal structure of tremelimumab Fab 分子名称: heavy chain, light chain 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2016-11-16 実験手法 X-RAY DIFFRACTION (2.292 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
5GGS	PD-1 in complex with pembrolizumab Fab 分子名称: Programmed cell death protein 1, heavy chain, light chain 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2016-11-16 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
6UAQ	Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase from Amycolatopsis mediterranei (AmGH128_I) 分子名称: GLYCEROL, Glyco_hydro_cc domain-containing protein, SODIUM ION 著者 Costa, P.A.C.R, Santos, C.R, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
6UAW	Crystal structure of a GH128 (subgroup II) endo-beta-1,3-glucanase from Pseudomonas viridiflava (PvGH128_II) in complex with laminaritriose 分子名称: Glyco_hydro_cc domain-containing protein, SULFATE ION, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose 著者 Santos, C.R, Costa, P.A.C.R, Lima, E.A, Mandelli, F, Murakami, M.T. 登録日 2019-09-11 公開日 2020-05-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020

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