1LUK
 
 | | NMR Structure of the Itk SH2 domain, Pro287cis, Energy minimized average structure | | 分子名称: | Tyrosine-protein kinase ITK/TSK | | 著者 | Mallis, R.J, Brazin, K.N, Fulton, B.F, Andreotti, A.H. | | 登録日 | 2002-05-22 | | 公開日 | 2002-11-27 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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4RDL
 | | Crystal structure of Norovirus Boxer P domain in complex with Lewis y tetrasaccharide | | 分子名称: | Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose | | 著者 | Hao, N, Chen, Y, Xia, M, Liu, W, Tan, M, Jiang, X, Li, X. | | 登録日 | 2014-09-19 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | | 主引用文献 | Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Protein Cell, 6, 2015
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3L4D
 | | Crystal structure of sterol 14-alpha demethylase (CYP51) from Leishmania infantum in complex with fluconazole | | 分子名称: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Lepesheva, G.I, Hargrove, T.Y, Wawrzak, Z, Waterman, M.R. | | 登録日 | 2009-12-19 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Substrate Preferences and Catalytic Parameters Determined by Structural Characteristics of Sterol 14{alpha}-Demethylase (CYP51) from Leishmania infantum.
J.Biol.Chem., 286, 2011
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1NUW
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate and Phosphate at pH 9.6 | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-01 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Metaphosphate in the active site of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
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1LUN
 | | NMR Structure of the Itk SH2 domain, Pro287trans, energy minimized average structure | | 分子名称: | Tyrosine-protein kinase ITK/TSK | | 著者 | Mallis, R.J, Brazin, K.N, Fulton, D.B, Andreotti, A.H. | | 登録日 | 2002-05-22 | | 公開日 | 2002-11-27 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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4AQY
 | | Structure of ribosome-apramycin complexes | | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Matt, T, Ng, C.L, Lang, K, Sha, S.H, Akbergenov, R, Shcherbakov, D, Meyer, M, Duscha, S, Xie, J, Dubbaka, S.R, Perez-Fernandez, D, Vasella, A, Ramakrishnan, V, Schacht, J, Bottger, E.C. | | 登録日 | 2012-04-20 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2ERF
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1NUX
 | | Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and inhibitory concentrations of Potassium (200mM) | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, MAGNESIUM ION, ... | | 著者 | Choe, J, Iancu, C.V, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2003-02-01 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Metaphosphate in the active site of fructose-1,6-bisphosphatase
J.BIOL.CHEM., 278, 2003
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1M26
 | | Crystal structure of jacalin-T-antigen complex | | 分子名称: | Jacalin, alpha chain, beta chain, ... | | 著者 | Jeyaprakash, A.A, Rani, P.G, Reddy, G.B, Banumathi, S, Betzel, C, Surolia, A, Vijayan, M. | | 登録日 | 2002-06-21 | | 公開日 | 2002-10-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Crystal structure of the jacalin-T-antigen complex and a
comparative study of lectin-T-antigen complexs
J.Mol.Biol., 321, 2002
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4RDK
 | | Crystal structure of Norovirus Boxer P domain in complex with Lewis b tetrasaccharide | | 分子名称: | Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose | | 著者 | Hao, N, Chen, Y, Xia, M, Liu, W, Tan, M, Jiang, X, Li, X. | | 登録日 | 2014-09-19 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.629 Å) | | 主引用文献 | Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Protein Cell, 6, 2015
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4A8B
 | | Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes | | 分子名称: | LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ | | 著者 | Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. | | 登録日 | 2011-11-20 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (13 Å) | | 主引用文献 | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
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1O5B
 | | Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA) | | 分子名称: | 4-IODOBENZO[B]THIOPHENE-2-CARBOXAMIDINE, CITRIC ACID, Urokinase-type plasminogen activator | | 著者 | Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E. | | 登録日 | 2003-09-09 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA)
J.Mol.Biol., 344, 2004
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1O5G
 | | Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA) | | 分子名称: | 2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE, CALCIUM ION, Hirudin IIIB', ... | | 著者 | Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E. | | 登録日 | 2003-09-09 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
J.Mol.Biol., 344, 2004
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4RAF
 | | Crystal structure of PP2Ca-D38A | | 分子名称: | MANGANESE (II) ION, Protein phosphatase 1A | | 著者 | Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. | | 登録日 | 2014-09-10 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | The catalytic role of the M2 metal ion in PP2C alpha
Sci Rep, 5, 2015
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3ZVC
 | | 3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 82 | | 分子名称: | 3C PROTEASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(3-TERT-BUTOXY-3-OXOPROPYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE | | 著者 | Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R. | | 登録日 | 2011-07-24 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
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1KTL
 | | The human non-classical major histocompatibility complex molecule HLA-E | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | | 著者 | Holmes, M.A, Strong, R.K. | | 登録日 | 2002-01-16 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
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3KAA
 | | Structure of Tim-3 in complex with phosphatidylserine | | 分子名称: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, CALCIUM ION, Hepatitis A virus cellular receptor 2 | | 著者 | Ballesteros, A, Santiago, C, Casasnovas, J.M. | | 登録日 | 2009-10-19 | | 公開日 | 2010-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | | 主引用文献 | T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.
J.Immunol., 184, 2010
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3ZZP
 | | Circular permutant of ribosomal protein S6, lacking edge strand beta- 2 of wild-type S6. | | 分子名称: | RIBOSOMAL PROTEIN S6 | | 著者 | Saraboji, K, Haglund, E, Lindberg, M.O, Oliveberg, M, Logan, D.T. | | 登録日 | 2011-09-02 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | Trimming Down a Protein Structure to its Bare Foldons: Spatial Organization of the Cooperative Unit.
J.Biol.Chem., 287, 2012
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4QXX
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3JVA
 | | Crystal structure of Dipeptide Epimerase from Enterococcus faecalis V583 | | 分子名称: | Dipeptide Epimerase, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Fedorov, A.A, Fedorov, E.V, Sakai, A, Imker, H, Gerlt, J.A, Almo, S.C. | | 登録日 | 2009-09-16 | | 公開日 | 2010-08-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3ZVA
 | | 3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 75 | | 分子名称: | 3C PROTEASE, ETHYL (4R)-4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE | | 著者 | Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R. | | 登録日 | 2011-07-24 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
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3ZV9
 | | 3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 74 | | 分子名称: | 3C PROTEASE, ETHYL (4R)-4-[(TERT-BUTOXYCARBONYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE | | 著者 | Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R. | | 登録日 | 2011-07-24 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses.
J.Virol., 87, 2013
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2CGU
 | | Identification of chemically diverse Chk1 inhibitors by receptor- based virtual screening | | 分子名称: | 2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID, SERINE/THREONINE-PROTEIN KINASE CHK1 | | 著者 | Foloppe, N, Fisher, L.M, Howes, R, Potter, A, Robertson, A.G.S, Surgenor, A.E. | | 登録日 | 2006-03-09 | | 公開日 | 2006-04-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification of Chemically Diverse Chk1 Inhibitors by Receptor-Based Virtual Screening.
Bioorg.Med.Chem., 14, 2006
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3ZXV
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3ZTT
 | | Crystal structure of pneumococcal surface antigen PsaA with manganese | | 分子名称: | MANGANESE (II) ION, MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN | | 著者 | McDevitt, C.A, Ogunniyi, A.D, Valkov, E, Lawrence, M.C, Kobe, B, McEwan, A.G, Paton, J.C. | | 登録日 | 2011-07-12 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A molecular mechanism for bacterial susceptibility to zinc.
PLoS Pathog., 7, 2011
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