PDB: 35 件ウェブページステータス検索Chemie searchBIRD

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5ZCJ	Crystal structure of complex 分子名称: TP53-binding protein 1, Tudor-interacting repair regulator protein 著者 Wang, J, Yuan, Z, Cui, Y, Xie, R, Wang, M, Ma, Y, Yu, X, Liu, X. 登録日 2018-02-17 公開日 2018-06-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.004 Å) 主引用文献 Crystal structure of complex To Be Published
5Z78	Structure of TIRR/53BP1 complex 分子名称: TP53-binding protein 1, Tudor-interacting repair regulator protein 著者 Dai, Y.X, Shan, S. 登録日 2018-01-27 公開日 2018-06-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR Nat Commun, 9, 2018
6CO1	Structure of human TIRR in complex with 53BP1 Tudor domains 分子名称: TP53-binding protein 1, Tudor-interacting repair regulator protein 著者 Cui, G, Botuyan, M.V, Mer, G. 登録日 2018-03-10 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.179 Å) 主引用文献 Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25, 2018
7YQK	cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1 分子名称: DNA (145-MER), Histone H2AX, Histone H2B, ... 著者 Ai, H.S, GuoChao, C, Qingyue, G, Ze-Bin, T, Zhiheng, D, Xin, L, Fan, Y, Ziyu, X, Jia-Bin, L, Changlin, T, Liu, L. 登録日 2022-08-07 公開日 2022-08-17 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes. J.Am.Chem.Soc., 144, 2022
5J26	Crystal structure of a 53BP1 Tudor domain in complex with a ubiquitin variant 分子名称: Tumor suppressor p53-binding protein 1, Ubiquitin Variant i53 著者 Wan, L, Canny, M, Juang, Y.C, Durocher, D, Sicheri, F. 登録日 2016-03-29 公開日 2016-12-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.5047 Å) 主引用文献 A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing To Be Published
8SVG	Ubiquitin variant i53 in complex with 53BP1 Tudor domain 分子名称: Tumor protein p53 binding protein 1, Ubiquitin variant i53 著者 Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A. 登録日 2023-05-16 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nat Commun, 15, 2024
8SVH	Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain 分子名称: Tumor protein p53 binding protein 1, Ubiquitin variant i53: mutant L67R 著者 Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A. 登録日 2023-05-16 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nat Commun, 15, 2024
8SVI	Ubiquitin variant i53:Mutant L67H with 53BP1 Tudor domain 分子名称: GLYCEROL, Tumor protein p53 binding protein 1, Ubiquitin Variant i53: Mutant L67H 著者 Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A. 登録日 2023-05-16 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nat Commun, 15, 2024
8SVJ	Ubiquitin variant i53: mutant VHH with 53BP1 Tudor domain 分子名称: GLYCEROL, Tumor protein p53 binding protein 1, Ubiquitin varient i53 mutant VHH 著者 Holden, J, Partridge, J.R, Wibowo, A.S, Mulichak, A. 登録日 2023-05-16 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nat Commun, 15, 2024
8T2D	Ubiquitin variant i53:Mutant T12Y.T14E.L67R with 53BP1 Tudor domain 分子名称: Tumor protein p53 binding protein 1, Ubiquitin variant i53 著者 Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A. 登録日 2023-06-05 公開日 2024-03-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nat Commun, 15, 2024

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