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8GLK
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BU of 8glk by Molmil
The Type 9 Secretion System dGldL peak II, NucA substrate bound complex
分子名称: Endonuclease I, Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, ...
著者Deme, J.C, Lea, S.M.
登録日2023-03-22
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8GLN
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BU of 8gln by Molmil
The Type 9 Secretion System in vivo assembled, RemZ substrate bound complex - conformation 2
分子名称: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Protein involved in gliding motility SprA, ...
著者Deme, J.C, Lea, S.M.
登録日2023-03-22
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8GL8
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BU of 8gl8 by Molmil
The Type 9 Secretion System Extended Translocon - SprA-PorV-PPI-RemZ-SkpA-SprE complex
分子名称: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Periplasmic chaperone for outer membrane proteins Skp, ...
著者Deme, J.C, Lea, S.M.
登録日2023-03-21
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8GLM
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BU of 8glm by Molmil
The Type 9 Secretion System in vivo assembled, RemZ substrate bound complex - conformation 1
分子名称: Lauryl Maltose Neopentyl Glycol, Peptidyl-prolyl cis-trans isomerase, Protein involved in gliding motility SprA, ...
著者Deme, J.C, Lea, S.M.
登録日2023-03-22
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献The Type 9 Secretion System caught in the act of transport
Nat Microbiol, 2024
8DVV
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BU of 8dvv by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-29
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
To Be Published
8DTY
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BU of 8dty by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-26
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
8DTZ
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BU of 8dtz by Molmil
Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-26
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
8VK3
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BU of 8vk3 by Molmil
Structure of mouse RyR1 in complex with S100A1 (EGTA-only dataset)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Protein S100A1, ...
著者Weninger, G, Marks, A.R.
登録日2024-01-08
公開日2024-01-24
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structural insights into the regulation of RyR1 by S100A1.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VJK
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BU of 8vjk by Molmil
Structure of mouse RyR1 (high-Ca2+/CFF/ATP dataset)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ...
著者Weninger, G, Marks, A.R.
登録日2024-01-07
公開日2024-01-17
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Structural insights into the regulation of RyR1 by S100A1.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VJJ
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BU of 8vjj by Molmil
Structure of mouse RyR1 (EGTA-only dataset)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ...
著者Weninger, G, Marks, A.R.
登録日2024-01-07
公開日2024-01-17
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Structural insights into the regulation of RyR1 by S100A1.
Proc.Natl.Acad.Sci.USA, 121, 2024
8QMO
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BU of 8qmo by Molmil
Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ...
著者Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J.
登録日2023-09-24
公開日2024-01-10
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds.
J.Mol.Biol., 436, 2024
8X6P
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BU of 8x6p by Molmil
Isomerase Protein
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1A, SULFATE ION
著者Guven, O, Demirci, H.
登録日2023-11-21
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Isomerase Protein
To Be Published
8UXC
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BU of 8uxc by Molmil
Structure of PKA phosphorylated human RyR2-R420Q in the primed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UXE
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BU of 8uxe by Molmil
Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210
分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UXF
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BU of 8uxf by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXG
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BU of 8uxg by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210
分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UXH
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BU of 8uxh by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UXL
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BU of 8uxl by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXI
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BU of 8uxi by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXM
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BU of 8uxm by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UQ2
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BU of 8uq2 by Molmil
Structure of human RyR2-S2808D in the subprimed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-10-23
公開日2023-11-15
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UQ3
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BU of 8uq3 by Molmil
Structure of human RyR2-S2808D in the closed state in the presence of ARM210
分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-10-23
公開日2023-11-15
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8UQ4
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BU of 8uq4 by Molmil
Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-10-23
公開日2023-11-15
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Nat Commun, 15, 2024
8PC2
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BU of 8pc2 by Molmil
SelDeg51 in complex with FKBP51FK1 domain and pVHL:EloB:EloC
分子名称: Elongin-B, Elongin-C, Peptidyl-prolyl cis-trans isomerase FKBP5, ...
著者Meyners, C, Walz, M, Geiger, T.M, Hausch, F.
登録日2023-06-09
公開日2023-11-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51).
Angew.Chem.Int.Ed.Engl., 63, 2024
8PDF
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BU of 8pdf by Molmil
FKBP12 in complex with PROTAC 6a2
分子名称: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[4-[(1~{S})-1-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethenyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]ethyl]-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Peptidyl-prolyl cis-trans isomerase FKBP1A
著者Meyners, C, Walz, M, Geiger, T.M, Hausch, F.
登録日2023-06-12
公開日2023-11-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51).
Angew.Chem.Int.Ed.Engl., 63, 2024

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件を2024-09-25に公開中

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