8GLK
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8GLN
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8GL8
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8GLM
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8DVV
| Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | 著者 | Iyer, K.A, Hu, Y, Murayama, T, Samso, M. | 登録日 | 2022-07-29 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions To Be Published
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8DTY
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8DTZ
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8VK3
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8VJK
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8VJJ
| Structure of mouse RyR1 (EGTA-only dataset) | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... | 著者 | Weninger, G, Marks, A.R. | 登録日 | 2024-01-07 | 公開日 | 2024-01-17 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Structural insights into the regulation of RyR1 by S100A1. Proc.Natl.Acad.Sci.USA, 121, 2024
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8QMO
| Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | 著者 | Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J. | 登録日 | 2023-09-24 | 公開日 | 2024-01-10 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds. J.Mol.Biol., 436, 2024
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8X6P
| Isomerase Protein | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP1A, SULFATE ION | 著者 | Guven, O, Demirci, H. | 登録日 | 2023-11-21 | 公開日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Isomerase Protein To Be Published
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8UXC
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8UXE
| Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210 | 分子名称: | 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | 著者 | Miotto, M.C, Marks, A.R. | 登録日 | 2023-11-09 | 公開日 | 2023-11-22 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
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8UXF
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8UXG
| Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210 | 分子名称: | 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | 著者 | Miotto, M.C, Marks, A.R. | 登録日 | 2023-11-09 | 公開日 | 2023-11-22 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
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8UXH
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8UXL
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8UXI
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8UXM
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8UQ2
| Structure of human RyR2-S2808D in the subprimed state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | 著者 | Miotto, M.C, Marks, A.R. | 登録日 | 2023-10-23 | 公開日 | 2023-11-15 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
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8UQ3
| Structure of human RyR2-S2808D in the closed state in the presence of ARM210 | 分子名称: | 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | 著者 | Miotto, M.C, Marks, A.R. | 登録日 | 2023-10-23 | 公開日 | 2023-11-15 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024
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8UQ4
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8PC2
| SelDeg51 in complex with FKBP51FK1 domain and pVHL:EloB:EloC | 分子名称: | Elongin-B, Elongin-C, Peptidyl-prolyl cis-trans isomerase FKBP5, ... | 著者 | Meyners, C, Walz, M, Geiger, T.M, Hausch, F. | 登録日 | 2023-06-09 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51). Angew.Chem.Int.Ed.Engl., 63, 2024
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8PDF
| FKBP12 in complex with PROTAC 6a2 | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[4-[(1~{S})-1-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethenyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]ethyl]-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Peptidyl-prolyl cis-trans isomerase FKBP1A | 著者 | Meyners, C, Walz, M, Geiger, T.M, Hausch, F. | 登録日 | 2023-06-12 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51). Angew.Chem.Int.Ed.Engl., 63, 2024
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