PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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3MTB	Glycogen phosphorylase complexed with 3-chlorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(3-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3NC4	The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(2-hydroxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-06-04 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3NX3	Crystal structure of acetylornithine aminotransferase (argD) from Campylobacter jejuni 分子名称: Acetylornithine aminotransferase, MAGNESIUM ION 著者 Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Skarina, T, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-07-12 公開日 2010-08-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献
5T7D	Crystal structure of Streptomyces hygroscopicus bialaphos resistance (BAR) protein in complex with acetyl coenzyme A 分子名称: ACETATE ION, ACETYL COENZYME *A, Phosphinothricin N-acetyltransferase 著者 Christ, B, Weng, J.K. 登録日 2016-09-04 公開日 2017-06-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Non-specific activities of the major herbicide-resistance gene BAR. Nat Plants, 3, 2017
4GEB	Kynurenine Aminotransferase II Inhibitors 分子名称: (5-hydroxy-4-{[(7-hydroxy-6-oxo-2-phenyl-6,7-dihydro-2H-pyrazolo[3,4-b]pyridin-5-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, ... 著者 Pandit, J. 登録日 2012-08-01 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 PF-04859989 as a template for structure-based drug design: identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency. Bioorg.Med.Chem.Lett., 23, 2013
8CA0	Macrophage inhibitory factor (MIF) in complex with small molecule PAV174 分子名称: 1-ethyl-9-methyl-3,7-dipyrrolidin-1-yl-phenothiazine, Macrophage migration inhibitory factor 著者 Mueller, A, Torres, F, Roland, R, Korth, C. 登録日 2023-01-24 公開日 2024-02-07 実験手法 SOLUTION NMR 主引用文献 Oxidized MIF is a drug target at the molecular intersection between immune activation and tau cellular pathology To Be Published
5ALI	ligand complex structure of soluble epoxide hydrolase 分子名称: 1-[3-[5-(7-aminothiazolo[5,4-d]pyrimidin-2-yl)-1-[[(2S)-tetrahydrofuran-2-yl]methyl]imidazol-4-yl]phenyl]-3-(4-methoxyphenyl)urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
9BTS	Crystal structure of the bacterioferritin (Bfr) and ferritin (Ftn) heterooligomer complex from Acinetobacter baumannii 分子名称: Bacterioferritin (Bfr), Ferritin (Ftn), PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Lovell, S, Liu, L, Battaile, K.P, Rivera, M. 登録日 2024-05-15 公開日 2024-08-14 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The crystal structure of Acinetobacter baumannii bacterioferritin reveals a heteropolymer of bacterioferritin and ferritin subunits. Sci Rep, 14, 2024
5A2V	Crystal structure of mtPAP in Apo form 分子名称: CHLORIDE ION, MITOCHONDRIAL PROTEIN 著者 Lapkouski, M, Hallberg, B.M. 登録日 2015-05-26 公開日 2015-09-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
5A2Z	Crystal structure of mtPAP in complex with GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MITOCHONDRIAL PROTEIN 著者 Lapkouski, M, Hallberg, B.M. 登録日 2015-05-26 公開日 2015-09-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
5A2X	Crystal structure of mtPAP in complex with CTP 分子名称: CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MITOCHONDRIAL PROTEIN 著者 Lapkouski, M, Hallberg, B.M. 登録日 2015-05-26 公開日 2015-09-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
6FZY	PPAR mutant 分子名称: Peroxisome proliferator-activated receptor gamma 著者 Rochel, N. 登録日 2018-03-15 公開日 2019-02-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors. Nat Commun, 10, 2019
6FZG	PPAR gamma mutant complex 分子名称: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, CHLORIDE ION, Peroxisome proliferator-activated receptor gamma 著者 Rochel, N. 登録日 2018-03-14 公開日 2019-02-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors. Nat Commun, 10, 2019
6FZP	PPAR gamma complex. 分子名称: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 著者 Rochel, N, Beji, S. 登録日 2018-03-15 公開日 2019-02-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors. Nat Commun, 10, 2019
6FZF	PPAR mutant complex 分子名称: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 著者 Rochel, N. 登録日 2018-03-14 公開日 2019-02-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors. Nat Commun, 10, 2019
7L0F	Monobody 12VC3 Bound to HRAS(WT) 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ... 著者 Teng, K.W, Hattori, T, Tsai, S, Koide, S. 登録日 2020-12-11 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun, 12, 2021
7L0G	Monobody 12VC1 Bound to HRAS(G12C) 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ... 著者 Teng, K.W, Hattori, T, Tsai, S, Koide, S. 登録日 2020-12-11 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun, 12, 2021
6WO3	Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody U1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... 著者 Tzarum, N, Wilson, I.A, Law, M. 登録日 2020-04-24 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.382 Å) 主引用文献 An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6, 2020
6WO4	Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody HC11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... 著者 Tzarum, N, Wilson, I.A, Law, M. 登録日 2020-04-24 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6, 2020
6WOQ	Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... 著者 Tzarum, N, Wilson, I.A, Law, M. 登録日 2020-04-25 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.667 Å) 主引用文献 An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6, 2020
6WO5	Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody 212.1.1 and non neutralizing antibody E1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... 著者 Tzarum, N, Wilson, I.A, Law, M. 登録日 2020-04-24 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.619 Å) 主引用文献 An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6, 2020
4XSH	The complex structure of C3cer exoenzyme and GTP bound RhoA (NADH-bound state) 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... 著者 Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H. 登録日 2015-01-22 公開日 2015-06-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. J.Biol.Chem., 290, 2015
4XYP	Crystal structure of a piscine viral fusion protein 分子名称: 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, CHLORIDE ION, Fusion protein 著者 Cook, J.D, Lee, J.E. 登録日 2015-02-02 公開日 2015-06-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Electrostatic Architecture of the Infectious Salmon Anemia Virus (ISAV) Core Fusion Protein Illustrates a Carboxyl-Carboxylate pH Sensor. J.Biol.Chem., 290, 2015
5MFW	Crystal structure of the GluK1 ligand-binding domain in complex with kainate and BPAM-121 at 2.10 A resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, 7-chloro-4-(2-fluoroethyl)-2,3-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, ACETATE ION, ... 著者 Larsen, A.P, Frydenvang, K, Kastrup, J.S. 登録日 2016-11-18 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors. Mol. Pharmacol., 91, 2017
4XSG	The complex structure of C3cer exoenzyme and GTP bound RhoA (NADH-free state) 分子名称: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ADP-ribosyltransferase, ... 著者 Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H. 登録日 2015-01-22 公開日 2015-06-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. J.Biol.Chem., 290, 2015

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