PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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5I4V	Discovery of novel, orally efficacious Liver X Receptor (LXR) beta agonists 分子名称: Oxysterols receptor LXR-beta,Nuclear receptor coactivator 2, Retinoic acid receptor RXR-beta,Nuclear receptor coactivator 2, {2-[(2R)-4-[4-(hydroxymethyl)-3-(methylsulfonyl)phenyl]-2-(propan-2-yl)piperazin-1-yl]-4-(trifluoromethyl)pyrimidin-5-yl}methanol 著者 Chen, G, McKeever, B.M. 登録日 2016-02-12 公開日 2016-06-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) beta Agonist. J.Med.Chem., 59, 2016
4G76	Structure of PaeM, a colicin M-like bacteriocin produced by Pseudomonas aeruginosa 分子名称: Phosphodiesterase 著者 Touze, T, Graille, M, Mengin-Lecreulx, D. 登録日 2012-07-20 公開日 2012-09-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.385 Å) 主引用文献 Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa. J.Biol.Chem., 287, 2012
4GGK	Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate 分子名称: Mitochondrial cardiolipin hydrolase, TUNGSTATE(VI)ION, ZINC ION 著者 Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L. 登録日 2012-08-06 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature, 491, 2012
1WVJ	Exploring the GluR2 ligand-binding core in complex with the bicyclic AMPA analogue (S)-4-AHCP 分子名称: 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE, GLYCEROL, SULFATE ION, ... 著者 Nielsen, B.B, Pickering, D.S, Greenwood, J.R, Brehm, L, Gajhede, M, Schousboe, A, Kastrup, J.S. 登録日 2004-12-15 公開日 2005-04-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP FEBS J., 272, 2005
3MRV	Glycogen phosphorylase complexed with 3-hydroxybenzaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone 分子名称: DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ... 著者 Alexacou, K.-M. 登録日 2010-04-29 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3MT8	Glycogen phosphorylase complexed with 4-chlorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3MT7	Glycogen phosphorylase complexed with 4-bromobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-bromophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
1TVQ	Crystal Structure of Apo Chicken Liver Basic Fatty Acid Binding Protein (or Bile Acid Binding Protein) 分子名称: Fatty acid-binding protein 著者 Nichesola, D, Perduca, M, Capaldi, S, Carrizo, M.E, Righetti, P.G, Monaco, H.L. 登録日 2004-06-30 公開日 2004-11-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of chicken liver basic Fatty Acid-binding protein complexed with cholic acid Biochemistry, 43, 2004
1TW4	Crystal Structure of Chicken Liver Basic Fatty Acid Binding Protein (Bile Acid Binding Protein) Complexed With Cholic Acid 分子名称: CHOLIC ACID, Fatty acid-binding protein 著者 Nichesola, D, Perduca, M, Capaldi, S, Carrizo, M.E, Righetti, P.G, Monaco, H.L. 登録日 2004-06-30 公開日 2004-11-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of chicken liver basic Fatty Acid-binding protein complexed with cholic acid Biochemistry, 43, 2004
8HTG	Crystal structure of Golf in complex with GTP-gamma S and Mg 分子名称: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(olf) subunit alpha, ... 著者 Kang, H, Choi, H.-J. 登録日 2022-12-21 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family. Nat Commun, 14, 2023
3LV2	Crystal structure of Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase in complex with substrate analog sinefungin 分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SINEFUNGIN 著者 Dey, S, Sacchettini, J.C. 登録日 2010-02-19 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49, 2010
4UYA	Structure of MLK4 kinase domain with ATPgammaS 分子名称: MAGNESIUM ION, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLK4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Read, J.A, Brassington, C, Pollard, H.K, Phillips, C, Green, I, Overmann, R, Collier, M. 登録日 2014-08-29 公開日 2015-09-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Recurrent Mlk4 Loss-of-Function Mutations Suppress Jnk Signaling to Promote Colon Tumorigenesis. Cancer Res., 76, 2016
3BR1	Crystal Structure of the Complex of Dequalinium Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: DEQUALINIUM, HTH-type transcriptional regulator qacR, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
2Q9E	Structure of spin-labeled T4 lysozyme mutant S44R1 分子名称: 2-HYDROXYETHYL DISULFIDE, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate 著者 Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. 登録日 2007-06-12 公開日 2007-06-26 最終更新日 2023-08-30 実験手法 EPR (2.1 Å), X-RAY DIFFRACTION 主引用文献 Structural determinants of nitroxide motion in spin-labeled proteins: Solvent-exposed sites in helix B of T4 lysozyme. Protein Sci., 17, 2008
3BR2	Crystal Structure of the Complex of Dequalinium Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: DEQUALINIUM, HTH-type transcriptional regulator qacR, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BR3	Crystal Structure of the Complex of Ethidium Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: ETHIDIUM, HTH-type transcriptional regulator qacR, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BR0	Crystal Structure of the Complex of Malachite Green Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: HTH-type transcriptional regulator qacR, IMIDAZOLE, MALACHITE GREEN, ... 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BQZ	Crystal Structure of the Complex of Malachite Green Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: HTH-type transcriptional regulator qacR, IMIDAZOLE, MALACHITE GREEN, ... 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BR6	Crystal Structure of the Complex of Rhodamine 6G Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: HTH-type transcriptional regulator qacR, RHODAMINE 6G, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
3BR5	Crystal Structure of the Complex of Rhodamine 6G Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor 分子名称: HTH-type transcriptional regulator qacR, RHODAMINE 6G, SULFATE ION 著者 Brooks, B.E. 登録日 2007-12-20 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Formal electrostatic interactions do not govern QacR-cation affinity To be Published
2Q9D	Structure of spin-labeled T4 lysozyme mutant A41R1 分子名称: BETA-MERCAPTOETHANOL, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate 著者 Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. 登録日 2007-06-12 公開日 2007-06-26 最終更新日 2023-08-30 実験手法 EPR (1.4 Å), X-RAY DIFFRACTION 主引用文献 Structural determinants of nitroxide motion in spin-labeled proteins: Solvent-exposed sites in helix B of T4 lysozyme. Protein Sci., 17, 2008
3D1M	Crystal Structure of Sonic Hedgehog Bound to the third FNIII domain of CDO 分子名称: CALCIUM ION, Cell adhesion molecule, Sonic hedgehog protein, ... 著者 McLellan, J.S, Leahy, D.J. 登録日 2008-05-06 公開日 2008-09-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla. Nature, 455, 2008
1SVJ	The solution structure of the nucleotide binding domain of KdpB 分子名称: Potassium-transporting ATPase B chain 著者 Haupt, M, Bramkamp, M, Coles, M, Altendorf, K, Kessler, H. 登録日 2004-03-29 公開日 2004-09-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Inter-domain motions of the N-domain of the KdpFABC complex, a P-type ATPase, are not driven by ATP-induced conformational changes. J.Mol.Biol., 342, 2004
4W1W	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with 7-(diethylamino)-3-(thiophene-2-carbonyl)-2H-chromen-2-one 分子名称: 1,2-ETHANEDIOL, 7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, ... 著者 Finzel, B.C, Ran, D. 登録日 2014-08-13 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis. Chem.Biol., 22, 2015
1U7Q	THE SOLUTION STRUCTURE OF THE NUCLEOTIDE BINDING DOMAIN OF KDPB 分子名称: Potassium-transporting ATPase B chain 著者 Haupt, M, Bramkamp, M, Coles, M, Altendorf, K, Kessler, H. 登録日 2004-08-04 公開日 2004-09-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Inter-domain motions of the N-domain of the KdpFABC complex, a P-type ATPase, are not driven by ATP-induced conformational changes. J.Mol.Biol., 342, 2004

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