2VET
| CRYSTAL STRUCTURE OF THE THYMIDYLATE SYNTHASE K48Q COMPLEXED WITH DUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | 著者 | Sotelo-Mundo, R.R, Arreola, R, Maley, F, Montfort, W.R. | 登録日 | 2007-10-26 | 公開日 | 2007-12-04 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Role of an Invariant Lysine Residue in Folate Binding on Escherichia Coli Thymidylate Synthase: Calorimetric and Crystallographic Analysis of the K48Q Mutant. Int.J.Biochem.Cell Biol., 40, 2008
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4RYP
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7ZCU
| PucA-LH2 complex from Rps. palustris | 分子名称: | 1,2-Dihydro-psi,psi-caroten-1-ol, BACTERIOCHLOROPHYLL A, Light-harvesting protein B-800-850 alpha chain, ... | 著者 | Qian, P, Cogdell, R.J. | 登録日 | 2022-03-28 | 公開日 | 2022-10-12 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM structures of light-harvesting 2 complexes from Rhodopseudomonas palustris reveal the molecular origin of absorption tuning. Proc.Natl.Acad.Sci.USA, 119, 2022
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2VAT
| Crystal structure of deacetylcephalosporin C acetyltransferase in complex with coenzyme A | 分子名称: | ACETATE ION, ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE, COENZYME A, ... | 著者 | Lejon, S, Ellis, J, Valegard, K. | 登録日 | 2007-09-04 | 公開日 | 2008-09-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Last Step in Cephalosporin C Formation Revealed: Crystal Structures of Deacetylcephalosporin C Acetyltransferase from Acremonium Chrysogenum in Complexes with Reaction Intermediates. J.Mol.Biol., 377, 2008
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2VG3
| Rv2361 with citronellyl pyrophosphate | 分子名称: | CHLORIDE ION, GERANYL DIPHOSPHATE, GLYCEROL, ... | 著者 | Naismith, J.H, Wang, W, Dong, C. | 登録日 | 2007-11-08 | 公開日 | 2008-05-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structural basis of chain length control in Rv1086. J. Mol. Biol., 381, 2008
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2VF6
| Human FDPS synthase in complex with minodronate | 分子名称: | (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), FARNESYL PYROPHOSPHATE SYNTHETASE, MAGNESIUM ION | 著者 | Evdokimov, A.G, Barnett, B.L, Ebetino, F.H, Pokross, M. | 登録日 | 2007-10-31 | 公開日 | 2007-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Human Fdps Synthase in Complex with Novel Inhibitor To be Published
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6BXL
| Crystal structure of Pyrococcus horikoshii Dph2 with 4Fe-4S cluster and SAM | 分子名称: | 2-(3-amino-3-carboxypropyl)histidine synthase, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE | 著者 | Torelli, A.T, Fenwick, M.K, Zhang, Y, Dong, M, Kathiresan, V, Carantoa, J.D, Dzikovski, B, Lancaster, K.M, Freed, J.H, Hoffman, B.M, Lin, H, Ealick, S.E. | 登録日 | 2017-12-18 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis. Science, 359, 2018
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7B3A
| Crystal structure of PamZ | 分子名称: | ACETATE ION, ACETYL COENZYME *A, CHLORIDE ION, ... | 著者 | Loll, B, Dang, T, Mainz, A, Suessmuth, R, Wahl, M.C. | 登録日 | 2020-11-30 | 公開日 | 2021-11-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Molecular basis of antibiotic self-resistance in a bee larvae pathogen. Nat Commun, 13, 2022
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4TN0
| Crystal Structure of the C-terminal Periplasmic Domain of Phosphoethanolamine Transferase EptC from Campylobacter jejuni | 分子名称: | UPF0141 protein yjdB, ZINC ION | 著者 | Fage, C.D, Brown, D, Boll, J.M, Keatinge-Clay, A.T, Trent, M.S. | 登録日 | 2014-06-02 | 公開日 | 2014-10-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystallographic study of the phosphoethanolamine transferase EptC required for polymyxin resistance and motility in Campylobacter jejuni. Acta Crystallogr.,Sect.D, 70, 2014
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2VB9
| beta-ketoacyl-ACP synthase I (KAS) from E. coli, apo structure | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, CHLORIDE ION | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | 登録日 | 2007-09-06 | 公開日 | 2007-12-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis. Acta Crystallogr.,Sect.D, 63, 2007
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4TNI
| RT XFEL structure of Photosystem II 500 ms after the third illumination at 4.6 A resolution | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | 著者 | Kern, J, Tran, R, Alonso-Mori, R, Koroidov, S, Echols, N, Hattne, J, Ibrahim, M, Gul, S, Laksmono, H, Sierra, R.G, Gildea, R.J, Han, G, Hellmich, J, Lassalle-Kaiser, B, Chatterjee, R, Brewster, A, Stan, C.A, Gloeckner, C, Lampe, A, DiFiore, D, Milathianaki, D, Fry, A.R, Seibert, M.M, Koglin, J.E, Gallo, E, Uhlig, J, Sokaras, D, Weng, T.-C, Zwart, P.H, Skinner, D.E, Bogan, M.J, Messerschmidt, M, Glatzel, P, Williams, G.J, Boutet, S, Adams, P.D, Zouni, A, Messinger, J, Sauter, N.K, Bergmann, U, Yano, J, Yachandra, V.K. | 登録日 | 2014-06-04 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | 主引用文献 | Taking snapshots of photosynthetic water oxidation using femtosecond X-ray diffraction and spectroscopy. Nat Commun, 5, 2014
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8F4A
| Crystal structure of acetyltransferase Eis from M. tuberculosis in complex with chlorhexidine | 分子名称: | 1-[6-[azanylidene-[[azanylidene-[[(4-chlorophenyl)amino]methyl]-$l^{4}-azanyl]methyl]-$l^{4}-azanyl]hexyl]-3-[~{N}-(4-chlorophenyl)carbamimidoyl]guanidine, GLYCEROL, N-acetyltransferase Eis | 著者 | Pang, A.H, Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. | 登録日 | 2022-11-10 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Discovery and Mechanistic Analysis of Structurally Diverse Inhibitors of Acetyltransferase Eis among FDA-Approved Drugs. Biochemistry, 62, 2023
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7CTZ
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5KOF
| Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and Acyl Carrier Protein, AcpP | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-(prop-2-enoylamino)ethylamino]propyl]amino]butyl] dihydrogen phosphate | 著者 | Milligan, J.C, Jackson, D.R, Barajas, J.F, Tsai, S.C. | 登録日 | 2016-06-30 | 公開日 | 2018-01-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis for interactions between an acyl carrier protein and a ketosynthase. Nat.Chem.Biol., 15, 2019
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7CB3
| Crystal structure of type III polyketide synthase from Mycobacterium marinum | 分子名称: | ACETATE ION, Chalcone/stilbene synthase, MYRISTIC ACID, ... | 著者 | Pratap, S, Kant, A, Saxena, P, Krishnan, V. | 登録日 | 2020-06-10 | 公開日 | 2022-06-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Crystal structure of type III polyketide synthase from Mycobacterium marinum. To Be Published
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5KTC
| FdhC with bound products: Coenzyme A and 3-[(R)-3-hydroxybutanoylamino]-3,6-dideoxy-d-galactose | 分子名称: | 1,2-ETHANEDIOL, COENZYME A, FdhC, ... | 著者 | Salinger, A.J, Thoden, J.B, Holden, H.M. | 登録日 | 2016-07-11 | 公開日 | 2016-07-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and Functional Investigation of FdhC from Acinetobacter nosocomialis: A Sugar N-Acyltransferase Belonging to the GNAT Superfamily. Biochemistry, 55, 2016
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6TV6
| Octameric McsB from Bacillus subtilis. | 分子名称: | MAGNESIUM ION, Protein-arginine kinase | 著者 | Suskiewicz, M.J, Hajdusits, B, Meinhart, A, Clausen, T. | 登録日 | 2020-01-09 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation. Elife, 10, 2021
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6RYZ
| SalL with S-adenosyl methionine | 分子名称: | 1,2-ETHANEDIOL, Adenosyl-chloride synthase, CHLORIDE ION, ... | 著者 | McKean, I, Frese, A, Cuetos, A, Burley, G, Grogan, G. | 登録日 | 2019-06-12 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | S-Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C-Alkylation. Angew.Chem.Int.Ed.Engl., 58, 2019
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6BNF
| Crystal structure of the intrinsic colistin resistance enzyme ICR(Mc) from Moraxella catarrhalis, catalytic domain, mono-zinc complex | 分子名称: | ACETATE ION, GLYCEROL, PHOSPHATE ION, ... | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Di Leo, R, Savchenko, A, Anderson, W.F, Satchell, K.J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-11-16 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Substrate recognition by a colistin resistance enzyme from Moraxella catarrhalis. ACS Chem. Biol., 2018
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2VBQ
| Structure of AAC(6')-Iy in complex with bisubstrate analog CoA-S- monomethyl-acetylneamine. | 分子名称: | (3R,9Z)-17-[(2R,3S,4R,5R,6R)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-3,4-dihydroxytetrahydro-2H-pyran-2-yl]-3-hydroxy-2,2-dimethyl-4,8,15-trioxo-12-thia-5,9,16-triazaheptadec-9-en-1-yl [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE, GLYCEROL, ... | 著者 | Vetting, M.W, Magalhaes, M.L, Freiburger, L, Gao, F, Auclair, K, Blanchard, J.S. | 登録日 | 2007-09-14 | 公開日 | 2008-01-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Kinetic and Structural Analysis of Bisubstrate Inhibition of the Salmonella Enterica Aminoglycoside 6'-N-Acetyltransferase. Biochemistry, 47, 2008
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7D3E
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6R38
| T. brucei FPPS in complex with 2-(2,5-dichlorobenzo[b]thiophen-3-yl)acetic acid | 分子名称: | 2-[2,5-bis(chloranyl)-1-benzothiophen-3-yl]ethanoic acid, DIMETHYL SULFOXIDE, Farnesyl pyrophosphate synthase | 著者 | Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W. | 登録日 | 2019-03-19 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery Thesis, 2019
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4BMH
| Crystal structure of SsHAT | 分子名称: | ACETYLTRANSFERASE, CHLORIDE ION | 著者 | He, Y, Turkenburg, J.P, Davies, G.J. | 登録日 | 2013-05-08 | 公開日 | 2014-01-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Three-Dimensional Structure of a Streptomyces Sviceus Gnat Acetyltransferase with Similarity to the C-Terminal Domain of the Human Gh84 O-Glcnacase Acta Crystallogr.,Sect.D, 70, 2014
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6V9K
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3JUW
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