PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

---

1AZS	COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GS-ALPHA, IIC2, ... 著者 Tesmer, J.J.G, Sprang, S.R. 登録日 1997-11-20 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS. Science, 278, 1997
5O2T	Human KRAS in complex with darpin K27 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase KRas, MAGNESIUM ION, ... 著者 Debreczeni, J.E, Guillard, S, Kolasinska-Zwierz, P, Breed, J, Zhang, J, Bery, N, Marwood, R, Tart, J, Stocki, P, Mistry, B, Phillips, C, Rabbitts, T, Jackson, R, Minter, R. 登録日 2017-05-22 公開日 2017-07-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange. Nat Commun, 8, 2017
2BTR	STRUCTURE OF CDK2 COMPLEXED WITH PNU-198873 分子名称: CELL DIVISION PROTEIN KINASE 2, N-(5-ISOPROPYL-THIAZOL-2-YL)-2-PYRIDIN-3-YL-ACETAMIDE 著者 Vulpetti, A, Casale, E, Roletto, F, Amici, R, Villa, M, Pevarello, P. 登録日 2005-06-06 公開日 2005-11-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-Based Drug Design to the Discovery of New 2-Aminothiazole Cdk2 Inhibitors. J.Mol.Graph.Model., 24, 2006
7B1P	Crystal Structure of Human BACE-1 in Complex with Compound 38a (NB-854) 分子名称: Beta-secretase 1, ~{N}-[3-[(3~{R},6~{R})-5-azanyl-3,6-dimethyl-6-(trifluoromethyl)-2~{H}-1,4-oxazin-3-yl]phenyl]-5-bromanyl-pyridine-2-carboxamide 著者 Rondeau, J.M, Wirth, E. 登録日 2020-11-25 公開日 2021-04-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Synthesis of the Potent, Selective, and Efficacious beta-Secretase (BACE1) Inhibitor NB-360. J.Med.Chem., 64, 2021
7B1Q	Crystal Structure of Human BACE-1 in Complex with Compound NB-360 (compound 54) 分子名称: Beta-secretase 1, ~{N}-[3-[(3~{R},6~{R})-5-azanyl-3,6-dimethyl-6-(trifluoromethyl)-2~{H}-1,4-oxazin-3-yl]-4-fluoranyl-phenyl]-5-cyano-3-methyl-pyridine-2-carboxamide 著者 Rondeau, J.M, Wirth, E. 登録日 2020-11-25 公開日 2021-04-28 最終更新日 2021-05-05 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Synthesis of the Potent, Selective, and Efficacious beta-Secretase (BACE1) Inhibitor NB-360. J.Med.Chem., 64, 2021
7B1E	BACE1 IN COMPLEX WITH compound 3 (NB-641) 分子名称: Beta-secretase 1, ~{N}-[3-[(4~{S})-2-azanyl-4-methyl-5,6-dihydro-1,3-thiazin-4-yl]phenyl]-5-bromanyl-pyridine-2-carboxamide 著者 Rondeau, J.M, Wirth, E. 登録日 2020-11-24 公開日 2021-04-28 最終更新日 2021-05-05 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Synthesis of the Potent, Selective, and Efficacious beta-Secretase (BACE1) Inhibitor NB-360. J.Med.Chem., 64, 2021
1W6J	Structure of human OSC in complex with Ro 48-8071 分子名称: LANOSTEROL SYNTHASE, TETRADECANE, [4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE, ... 著者 Thoma, R, Schulz-Gasch, T, D'Arcy, B, Benz, J, Aebi, J, Dehmlow, H, Hennig, M, Ruf, A. 登録日 2004-08-18 公開日 2004-10-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insight Into Steroid Scaffold Formation from the Structure of Human Oxidosqualene Cyclase Nature, 432, 2004
1W6K	Structure of human OSC in complex with Lanosterol 分子名称: LANOSTEROL, LANOSTEROL SYNTHASE, octyl beta-D-glucopyranoside 著者 Thoma, R, Schulz-Gasch, T, D'Arcy, B, Benz, J, Aebi, J, Dehmlow, H, Hennig, M, Ruf, A. 登録日 2004-08-19 公開日 2004-10-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Insight Into Steroid Scaffold Formation from the Structure of Human Oxidosqualene Cyclase Nature, 432, 2004
2AIX	X-ray structure of the GLUR2 ligand-binding core (S1S2J) in complex with (s)-thio-atpa at 2.2 a resolution. 分子名称: (S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-YL) PROPRIONIC ACID, Glutamate receptor 2 著者 Kastrup, J.S. 登録日 2005-08-01 公開日 2005-08-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Distinct kinetics of ionotropic glutamate receptor 2 splice variants characterized by fast agonist application and crystallization of a receptor-ligand complex. To be Published
2N3P	SOLUTION NMR STRUCTURE of ASTEROPSIN G from MARINE SPONGE ASTEROPUS 分子名称: Asteropsin_G 著者 Su, M, Jung, J.H. 登録日 2015-06-09 公開日 2016-06-08 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Stable and non-cytotoxic cystine knot peptides from a marine sponge asteropus To be Published
2N2G	SOLUTION NMR STRUCTURE of ASTEROPSIN F FROM MARINE SPONGE ASTEROPUS 分子名称: Asteropsin_F 著者 Su, M, Jung, J.H. 登録日 2015-05-07 公開日 2016-06-08 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Stable and non-cytotoxic cystine knot peptides from a marine sponge To be Published
1CHV	ELUCIDATION OF THE SOLUTION STRUCTURE OF CARDIOTOXIN ANALOGUE V FROM THE TAIWAN COBRA (NAJA NAJA ATRA) VENOM 分子名称: PROTEIN (CARDIOTOXIN ANALOGUE V) 著者 Jayaraman, G, Kumar, T.K.S, Tsai, C.C, Yu, C. 登録日 1999-03-30 公開日 2000-03-30 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Elucidation of the solution structure of cardiotoxin analogue V from the Taiwan cobra (Naja naja atra)--identification of structural features important for the lethal action of snake venom cardiotoxins Protein Sci., 9, 2000
2PYY	Crystal Structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with (L)-glutamate 分子名称: GLUTAMIC ACID, Ionotropic glutamate receptor bacterial homologue 著者 Lee, J.H, Kang, G.B, Lim, H.-H, Ree, M, Park, C.-S, Eom, S.H. 登録日 2007-05-17 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with L-glutamate: structural dissection of the ligand interaction and subunit interface. J.Mol.Biol., 376, 2008
2M6X	Structure of the p7 channel of Hepatitis C virus, genotype 5a 分子名称: p7 著者 OuYang, B, Chou, J.J. 登録日 2013-04-12 公開日 2013-06-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Unusual architecture of the p7 channel from hepatitis C virus Nature, 498, 2013
3EJF	Crystal structure of IBV X-domain at pH 8.5 分子名称: Non-structural protein 3 著者 Piotrowski, Y, Hansen, G, Hilgenfeld, R. 登録日 2008-09-18 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property. Protein Sci., 18, 2009
4P6A	Crystal structure of a potent anti-HIV lectin actinohivin in complex with alpha-1,2-mannotriose 分子名称: Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose 著者 Zhang, F, Hoque, M.M, Suzuki, K, Tsunoda, M, Naomi, O, Tanaka, H, Takenaka, A. 登録日 2014-03-23 公開日 2015-03-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.398 Å) 主引用文献 The characteristic structure of anti-HIV actinohivin in complex with three HMTG D1 chains of HIV-gp120. Chembiochem, 15, 2014
3EKE	Crystal structure of IBV X-domain at pH 5.6 分子名称: L(+)-TARTARIC ACID, Non-structural protein 3 著者 Piotrowski, Y, Hansen, G, Hilgenfeld, R. 登録日 2008-09-19 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property. Protein Sci., 18, 2009
5I2K	Structure of the human GluN1/GluN2A LBD in complex with 7-{[ethyl(4-fluorophenyl)amino]methyl}-N,2-dimethyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide (compound 19) 分子名称: 7-{[ethyl(4-fluorophenyl)amino]methyl}-N,2-dimethyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide, GLUTAMIC ACID, GLYCINE, ... 著者 Wallweber, H.J.A, Lupardus, P.J. 登録日 2016-02-09 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. J.Med.Chem., 59, 2016
3EJG	Crystal structure of HCoV-229E X-domain 分子名称: Non-structural protein 3 著者 Piotrowski, Y, Hansen, G, Hilgenfeld, R. 登録日 2008-09-18 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property. Protein Sci., 18, 2009
3CTK	Crystal structure of the type 1 RIP bouganin 分子名称: rRNA N-glycosidase 著者 Fermani, S, Tosi, G, Falini, G, Ripamonti, A, Farini, V, Bolognesi, A, Polito, L. 登録日 2008-04-14 公開日 2008-05-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure/function studies on two type 1 ribosome inactivating proteins: Bouganin and lychnin. J.Struct.Biol., 168, 2009
4W1V	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with a thiazole inhibitor 分子名称: 1,2-ETHANEDIOL, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, CHLORIDE ION, ... 著者 Finzel, B.C, Dai, R. 登録日 2014-08-13 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis. Chem.Biol., 22, 2015
6PGZ	MTSL labelled T4 lysozyme pseudo-wild type V75C mutant 分子名称: CHLORIDE ION, Endolysin, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate 著者 Cuneo, M.J, Myles, D.A, Li, L. 登録日 2019-06-25 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Making hydrogens stand out: Enhanced neutron diffraction from biological crystals using dynamic nuclear polarization To be published
2D43	Crystal structure of arabinofuranosidase complexed with arabinotriose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose, alpha-L-arabinofuranosidase B 著者 Miyanaga, A, Koseki, T, Miwa, Y, Matsuzawa, H, Wakagi, T, Shoun, H, Fushinobu, S. 登録日 2005-10-07 公開日 2006-09-19 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The family 42 carbohydrate-binding module of family 54 alpha-L-arabinofuranosidase specifically binds the arabinofuranose side chain of hemicellulose Biochem.J., 399, 2006
4W1X	Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with 1-(4-(4-(3-chlorobenzoyl)piperazin-1-yl)phenyl)ethanone 分子名称: 1,2-ETHANEDIOL, 1-{4-[4-(3-chlorobenzoyl)piperazin-1-yl]phenyl}ethanone, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, ... 著者 Finzel, B.C, Dai, R. 登録日 2014-08-13 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis. Chem.Biol., 22, 2015
1U65	Ache W. CPT-11 分子名称: (4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... 著者 Harel, M, Hyatt, J.L, Brumshtein, B, Morton, C.L, Wadkins, R.W, Silman, I, Sussman, J.L, Potter, P.M, Israel Structural Proteomics Center (ISPC) 登録日 2004-07-29 公開日 2005-07-19 最終更新日 2021-06-02 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action Mol.Pharmacol., 67, 2005

<178179180181182183184185186187188189190191192193>