PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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1FIE	RECOMBINANT HUMAN COAGULATION FACTOR XIII 分子名称: COAGULATION FACTOR XIII 著者 Yee, V.C, Teller, D.C. 登録日 1996-08-24 公開日 1997-02-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural evidence that the activation peptide is not released upon thrombin cleavage of factor XIII. Thromb.Res., 78, 1995
1QLE	CRYO-STRUCTURE OF THE PARACOCCUS DENITRIFICANS FOUR-SUBUNIT CYTOCHROME C OXIDASE IN THE COMPLETELY OXIDIZED STATE COMPLEXED WITH AN ANTIBODY FV FRAGMENT 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, CCYTOCHROME C OXIDASE, ... 著者 Harrenga, A, Michel, H. 登録日 1999-08-30 公開日 1999-12-02 最終更新日 2022-05-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Cytochrome C Oxidase from Paracoccus Denitrificans Does not Change the Metal Center Ligation Upon Reduction J.Biol.Chem., 274, 1999
1GS3	High resolution crystal structure of PI delta-5-3-Ketosteroid Isomerase mutants Y30F/Y55F/Y115F/D38N (Y32F/Y57F/Y119F/D40N, PI numbering)complexed with equilenin at 2.1 A resolution 分子名称: EQUILENIN, STEROID DELTA-ISOMERASE 著者 Shin, S, Ha, N.-C, Oh, B.-H. 登録日 2001-12-27 公開日 2003-01-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Contribution of a Low-Barrier Hydrogen Bond to Catalysis by Delta-5-3-Ketosteroid Isomerase is not Extremely High Compared to that of an Ordinary Hydrogen Bond. Low-Barrier Hydrogen Bond of Pi Ksi To be Published
1BZM	DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I 分子名称: CARBONIC ANHYDRASE I, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ZINC ION 著者 Chakravarty, S, Kannan, K.K. 登録日 1993-11-28 公開日 1994-04-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme. J.Mol.Biol., 243, 1994
2IBS	Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position 分子名称: 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... 著者 Pljevaljcic, G, Lenz, T, Scheidig, A.J, Weinhold, E. 登録日 2006-09-12 公開日 2007-05-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence J.Am.Chem.Soc., 129, 2007
2IBT	Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position 分子名称: 5'-D(*GP*AP*CP*AP*(3DR)P*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... 著者 Lenz, T, Scheidig, A.J, Weinhold, E. 登録日 2006-09-12 公開日 2007-05-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence J.Am.Chem.Soc., 129, 2007
2ATS	Dihydrodipicolinate synthase co-crystallised with (S)-lysine 分子名称: CHLORIDE ION, D-LYSINE, POTASSIUM ION, ... 著者 Devenish, S.R.A, Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. 登録日 2005-08-26 公開日 2006-09-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The co-crystallisation of (S)-lysine-bound dihydrodipicolinate synthase from E. coli indicates that domain movements are not responsible for (S)-lysine inhibition To be published
1LKA	Porcine Pancreatic Elastase/Ca-Complex 分子名称: ACETATE ION, CALCIUM ION, CHLORIDE ION, ... 著者 Weiss, M.S, Panjikar, S, Nowak, E, Tucker, P.A. 登録日 2002-04-24 公開日 2002-08-28 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Metal binding to porcine pancreatic elastase: calcium or not calcium. Acta Crystallogr.,Sect.D, 58, 2002
1H74	CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE 分子名称: ADENOSINE-5'-DIPHOSPHATE, HOMOSERINE KINASE, ISOLEUCINE, ... 著者 Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H. 登録日 2001-07-02 公開日 2001-11-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase Biochemistry, 40, 2001
1LKB	Porcine Pancreatic Elastase/Na-Complex 分子名称: CHLORIDE ION, Elastase 1, SODIUM ION, ... 著者 Weiss, M.S, Panjikar, S, Nowak, E, Tucker, P.A. 登録日 2002-04-24 公開日 2002-08-28 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Metal binding to porcine pancreatic elastase: calcium or not calcium. Acta Crystallogr.,Sect.D, 58, 2002
4GE7	Kynurenine Aminotransferase II Inhibitors 分子名称: (5-hydroxy-4-{[(1-hydroxy-2-oxo-6-phenoxy-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Pandit, J. 登録日 2012-08-01 公開日 2012-11-07 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions. ACS Med Chem Lett, 4, 2013
4GE4	Kynurenine Aminotransferase II Inhibitors 分子名称: (5-hydroxy-4-{[(1-hydroxy-7-methoxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Pandit, J. 登録日 2012-08-01 公開日 2012-11-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions. ACS Med Chem Lett, 4, 2013
4GDY	Kynurenine Aminotransferase II inhibitors 分子名称: (5-hydroxy-6-methyl-4-{[(1-oxo-7-phenoxy-1,2-dihydro[1,2,4]triazolo[4,3-a]quinolin-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Pandit, J. 登録日 2012-08-01 公開日 2012-08-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Discovery of Hydroxamate Bioisosteres as KATII Inhibitors with Improved Oral Bioavailability and Pharmacokinetics MEDCHEMCOMM, 2012
4GE9	Kynurenine Aminotransferase II Inhibitors 分子名称: (4-{[(6-benzyl-1-hydroxy-7-methoxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Pandit, J. 登録日 2012-08-01 公開日 2012-11-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions. ACS Med Chem Lett, 4, 2013
3DRD	Crystal Structure of 7,8 Diaminopelargonic Acid Synthase Apoenzyme in Bacillus subtilis 分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 著者 Dey, S, Sacchettini, J.C. 登録日 2008-07-11 公開日 2009-06-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49, 2010
3DU4	Crystal structure of 7-keto-8-aminopelargonic acid bound 7,8-diaminopelargonic acid synthase in bacillus subtilis 分子名称: 7-KETO-8-AMINOPELARGONIC ACID, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Dey, S, Sacchettini, J.C. 登録日 2008-07-16 公開日 2009-06-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49, 2010
3DOD	Crystal Structure of PLP Bound 7,8-Diaminopelargonic Acid Synthase in Bacillus subtilis 分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Dey, S, Sacchettini, J.C. 登録日 2008-07-03 公開日 2009-06-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49, 2010
2Z9S	Crystal Structure Analysis of rat HBP23/Peroxiredoxin I, Cys52Ser mutant 分子名称: Peroxiredoxin-1 著者 Matsumura, T, Okamoto, K, Nishino, T, Abe, Y. 登録日 2007-09-25 公開日 2007-11-20 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Dimer-Oligomer Interconversion of Wild-type and Mutant Rat 2-Cys Peroxiredoxin: DISULFIDE FORMATION AT DIMER-DIMER INTERFACES IS NOT ESSENTIAL FOR DECAMERIZATION J.Biol.Chem., 283, 2008
2KUH	Halothane binds to druggable sites in calcium-calmodulin: Solution structure of halothane-CaM C-terminal domain 分子名称: 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, CALCIUM ION, Calmodulin 著者 Juranic, N, Macura, S, Simeonov, M.V, Jones, K.A, Penheiter, A.R, Hock, T.J, Streiff, J.H. 登録日 2010-02-17 公開日 2010-03-09 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Halothane binds to druggable sites in the [Ca2+]4-calmodulin (CaM) complex, but does not inhibit [Ca2+]4-CaM activation of kinase. J. Serb. Chem. Soc., 78, 2013
2KUG	Halothane binds to druggable sites in calcium-calmodulin: Solution Structure of halothane-CaM N-terminal domain 分子名称: 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, CALCIUM ION, Calmodulin-1 著者 Juranic, N, Macura, S, Simeonov, M.V, Jones, K.A, Penheiter, A.R, Hock, T.J, Streiff, J.H. 登録日 2010-02-17 公開日 2010-03-09 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Halothane binds to druggable sites in the [Ca2+]4-calmodulin (CaM) complex, but does not inhibit [Ca2+]4-CaM activation of kinase. J. Serb. Chem. Soc., 78, 2013
1WQ8	Crystal structure of Vammin, a VEGF-F from a snake venom 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Vascular endothelial growth factor toxin 著者 Suto, K, Yamazaki, Y, Morita, T, Mizuno, H. 登録日 2004-09-23 公開日 2004-12-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1. J.Biol.Chem., 280, 2005
5A2Y	Crystal structure of mtPAP in complex with UTP 分子名称: MAGNESIUM ION, MITOCHONDRIAL PROTEIN, URIDINE 5'-TRIPHOSPHATE 著者 Lapkouski, M, Hallberg, B.M. 登録日 2015-05-26 公開日 2015-09-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype. Nucleic Acids Res., 43, 2015
5ACM	Mcg immunoglobulin variable domain with methylene blue 分子名称: 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, GLYCEROL, MCG, ... 著者 Brumshtein, B, Esswein, S.R, Salwinski, L, Phillips, M.L, Ly, A.T, Cascio, D, Sawaya, M.R, Eisenberg, D.S. 登録日 2015-08-17 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain. Elife, 4, 2015
1AZT	GS-ALPHA COMPLEXED WITH GTP-GAMMA-S 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GS-ALPHA, MAGNESIUM ION, ... 著者 Tesmer, J.J.G, Sprang, S.R. 登録日 1997-11-20 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the adenylyl cyclase activator Gsalpha Science, 278, 1997
1RLU	Mycobacterium tuberculosis FtsZ in complex with GTP-gamma-S 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein ftsZ, GLYCEROL 著者 Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W. 登録日 2003-11-26 公開日 2004-08-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches. J.Mol.Biol., 342, 2004

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