6WJN
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6WJD
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7W3H
| Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14 | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
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7W39
| Structure of USP14-bound human 26S proteasome in state EA2.1_UBL | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | 登録日 | 2021-11-25 | 公開日 | 2022-05-04 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
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9C57
| Reconstituted P400 Subcomplex of the human TIP60 complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | 著者 | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | 登録日 | 2024-06-05 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. Science, 385, 2024
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9C62
| P400 subcomplex of the native human TIP60 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | 著者 | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | 登録日 | 2024-06-07 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (5.28 Å) | 主引用文献 | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. Science, 385, 2024
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8X1C
| Structure of nucleosome-bound SRCAP-C in the ADP-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y. | 登録日 | 2023-11-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into histone exchange by human SRCAP complex. Cell Discov, 10, 2024
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8X15
| Structure of nucleosome-bound SRCAP-C in the apo state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y. | 登録日 | 2023-11-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into histone exchange by human SRCAP complex. Cell Discov, 10, 2024
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8X19
| Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y. | 登録日 | 2023-11-06 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into histone exchange by human SRCAP complex. Cell Discov, 10, 2024
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3QRL
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7P4S
| BROMODOMAIN OF HUMAN TAF1 (2) WITH naphthyridinone compound | 分子名称: | 8-[[1-(3-azanylpropyl)piperidin-4-yl]amino]-5-[5-(hydroxymethyl)pyridin-3-yl]-3-methyl-1~{H}-1,7-naphthyridin-2-one, Isoform 2a of Transcription initiation factor TFIID subunit 1 | 著者 | Chung, C. | 登録日 | 2021-07-13 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Optimization of Naphthyridones into Selective TATA-Binding Protein Associated Factor 1 (TAF1) Bromodomain Inhibitors. Acs Med.Chem.Lett., 12, 2021
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7ZBZ
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6BQD
| TAF1-BD2 bromodomain in complex with (E)-3-(6-(but-2-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide | 分子名称: | 3-{6-[(2E)-but-2-en-1-yl]-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl}-N,N-dimethylbenzamide, Transcription initiation factor TFIID subunit 1 | 著者 | Murray, J.M, Tang, Y. | 登録日 | 2017-11-27 | 公開日 | 2019-02-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.136 Å) | 主引用文献 | Water molecules in protein-ligand interfaces. Evaluation of software tools and SAR comparison. J. Comput. Aided Mol. Des., 33, 2019
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7Z8R
| CAND1-CUL1-RBX1 | 分子名称: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Baek, K, Schulman, B.A. | 登録日 | 2022-03-18 | 公開日 | 2023-04-19 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
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7Z8V
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7Z8T
| CAND1-SCF-SKP2 CAND1 engaged SCF rocked | 分子名称: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Baek, K, Schulman, B.A. | 登録日 | 2022-03-18 | 公開日 | 2023-04-19 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
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7ZBW
| CAND1-SCF-SKP2 CAND1 rolling-2 SCF engaged | 分子名称: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Baek, K, Schulman, B.A. | 登録日 | 2022-03-24 | 公開日 | 2023-04-19 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes. Cell, 186, 2023
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7QXN
| Proteasome-ZFAND5 Complex Z+A state | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-26 | 公開日 | 2023-02-08 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QXP
| Proteasome-ZFAND5 Complex Z+B state | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | 著者 | Zhu, Y, Lu, Y. | 登録日 | 2022-01-26 | 公開日 | 2023-02-08 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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6MSE
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6MSB
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6MSK
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6MSH
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6MSD
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8QR1
| Cryo-EM structure of the human Tip60 complex | 分子名称: | Actin, cytoplasmic 1, N-terminally processed, ... | 著者 | Li, C, Smirnova, E, Schnitzler, C, Crucifix, C, Concordet, J.P, Brion, A, Poterszman, A, Schultz, P, Papai, G, Ben-Shem, A. | 登録日 | 2023-10-06 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structure of human TIP60-C histone exchange and acetyltransferase complex Nature, 2024
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