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3PGX
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Crystal structure of a putative carveol dehydrogenase from Mycobacterium paratuberculosis bound to nicotinamide adenine dinucleotide
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, carveol dehydrogenase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-11-02
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
Sci Rep, 7, 2017
5W5A
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BU of 5w5a by Molmil
Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c)
分子名称: CHLORIDE ION, HTH-type transcriptional regulator Cmr, SULFATE ION
著者Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A.
登録日2017-06-14
公開日2017-12-13
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.
Nucleic Acids Res., 46, 2018
4RGB
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BU of 4rgb by Molmil
Crystal structure of a putative carveol dehydrogenase from Mycobacterium avium bound to NAD
分子名称: Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-09-29
公開日2014-10-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
Sci Rep, 7, 2017
5W5B
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BU of 5w5b by Molmil
Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c), truncated construct
分子名称: CHLORIDE ION, HTH-type transcriptional regulator Cmr
著者Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A.
登録日2017-06-14
公開日2017-12-13
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.
Nucleic Acids Res., 46, 2018
5OBW
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Mycoplasma genitalium DnaK-NBD in complex with ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ...
著者Adell, M, Calisto, B, Fita, I, Martinelli, L.
登録日2017-06-29
公開日2018-05-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone.
Protein Sci., 27, 2018
2BJB
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BU of 2bjb by Molmil
Mycobacterium Tuberculosis Epsp Synthase In Unliganded State
分子名称: 3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE, ACETATE ION, SODIUM ION
著者Bourenkov, G.P, Kachalova, G.S, Strizhov, N, Bruning, M, Vagin, A, Bartunik, H.D.
登録日2005-02-01
公開日2006-03-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mycobacterium Tuberculosis Epsp Synthase in Unliganded State
To be Published
5OBX
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Mycoplasma genitalium DnaK-NBD
分子名称: Chaperone protein DnaK, GLYCEROL, SULFATE ION, ...
著者Adell, M, Calisto, B, Fita, I, Martinelli, L.
登録日2017-06-29
公開日2018-05-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone.
Protein Sci., 27, 2018
6H27
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Structure of S70C BlaC from Mycobacterium tuberculosis
分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, BlaC
著者Tassoni, R, Pannu, N.S, Ubbink, M.
登録日2018-07-13
公開日2019-01-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献New Conformations of Acylation Adducts of Inhibitors of beta-Lactamase from Mycobacterium tuberculosis.
Biochemistry, 58, 2019
3PXX
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BU of 3pxx by Molmil
Crystal structure of carveol dehydrogenase from Mycobacterium avium bound to nicotinamide adenine dinucleotide
分子名称: Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-12-10
公開日2010-12-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
Sci Rep, 7, 2017
5OBY
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BU of 5oby by Molmil
Mycoplasma genitalium DnaK-NBD in complex with AMP-PNP
分子名称: Chaperone protein DnaK, GLYCEROL, MAGNESIUM ION, ...
著者Adell, M, Calisto, B, Fita, I, Martinelli, L.
登録日2017-06-29
公開日2018-05-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone.
Protein Sci., 27, 2018
5OBV
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BU of 5obv by Molmil
Mycoplasma genitalium DnaK deletion mutant lacking SBDalpha in complex with ADP and Pi.
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein DnaK, PHOSPHATE ION
著者Adell, M, Calisto, B, Fita, I, Martinelli, L.
登録日2017-06-29
公開日2018-05-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献The nucleotide-bound/substrate-bound conformation of the Mycoplasma genitalium DnaK chaperone.
Protein Sci., 27, 2018
1QTO
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BU of 1qto by Molmil
1.5 A CRYSTAL STRUCTURE OF A BLEOMYCIN RESISTANCE DETERMINANT FROM BLEOMYCIN-PRODUCING STREPTOMYCES VERTICILLUS
分子名称: BLEOMYCIN-BINDING PROTEIN
著者Kawano, Y, Kumagai, T, Muta, K, Matoba, Y, Davies, J, Sugiyama, M.
登録日1999-06-28
公開日2000-06-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The 1.5 A crystal structure of a bleomycin resistance determinant from bleomycin-producing Streptomyces verticillus.
J.Mol.Biol., 295, 2000
6PUX
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BU of 6pux by Molmil
Homoserine transacetylase MetX from Mycobacterium tuberculosis
分子名称: CHLORIDE ION, GLYCEROL, Homoserine O-acetyltransferase, ...
著者Chaton, C.T, Korotkov, K.V.
登録日2019-07-18
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site.
Sci Rep, 9, 2019
6C34
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Mycobacterium smegmatis DNA flap endonuclease mutant D125N
分子名称: 5'-3' exonuclease, MANGANESE (II) ION
著者Shuman, S, Goldgur, Y, Carl, A, Uson, M.L.
登録日2018-01-09
公開日2018-03-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
4RPI
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BU of 4rpi by Molmil
Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase from Mycobacterium tuberculosis
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, nicotinate-nucleotide adenylyltransferase
著者Rodionova, I, Zuccola, H, Sorci, L, Aleshin, A.E, Kazanov, M, Sergienko, E, Rubin, E, Locher, C, Osterman, A.
登録日2014-10-30
公開日2015-01-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.417 Å)
主引用文献Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery.
J. Biol. Chem., 290, 2015
6C36
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BU of 6c36 by Molmil
Mycobacterium smegmatis flap endonuclease mutant D208N
分子名称: 5'-3' exonuclease, MANGANESE (II) ION, PHOSPHATE ION
著者Shuman, S, Goldgur, Y, Carl, A, Uson, M.L.
登録日2018-01-09
公開日2018-03-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
6C33
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BU of 6c33 by Molmil
Mycobacterium smegmatis DNA flap endonuclease
分子名称: 5'-3' exonuclease, MANGANESE (II) ION
著者Shuman, S, Goldgur, Y, Carl, A, Uson, M.L.
登録日2018-01-09
公開日2018-03-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
6C35
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BU of 6c35 by Molmil
Mycobacterium smegmatis flap endonuclease mutant D148N
分子名称: 5'-3' exonuclease, MANGANESE (II) ION
著者Shuman, S, Goldgur, Y, Carl, A, Uson, M.L.
登録日2018-01-09
公開日2018-03-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
4UBW
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BU of 4ubw by Molmil
Apo structure of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis
分子名称: Acetyl-CoA acetyltransferase FadA5, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Schaefer, C.M, Kisker, C.
登録日2014-08-13
公開日2014-12-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献FadA5 a Thiolase from Mycobacterium tuberculosis: A Steroid-Binding Pocket Reveals the Potential for Drug Development against Tuberculosis.
Structure, 23, 2015
4Q6U
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BU of 4q6u by Molmil
Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis
分子名称: PENTAETHYLENE GLYCOL, Uncharacterized protein
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-04-23
公開日2014-06-18
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mycobacterium tuberculosis Rv3651 is a triple sensor-domain protein.
Protein Sci., 27, 2018
4W2I
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BU of 4w2i by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Szal, T, Jiang, F, Gupta, P, Matsuda, R, Shiozuka, M, Steitz, T.A, Vazquez-Laslop, N, Mankin, A.S.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA.
Mol.Cell, 56, 2014
5DRI
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BU of 5dri by Molmil
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-4-(1H-indol-5-yl)-4-oxobut-2-enoic acid inhibitor
分子名称: (2Z)-2-hydroxy-4-(1H-indol-5-yl)-4-oxobut-2-enoic acid, MAGNESIUM ION, Malate synthase G
著者Krieger, I.V, Huang, H.-L, Sacchettini, J.C.
登録日2015-09-15
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange.
J. Biol. Chem., 291, 2016
4XTX
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Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor 57 with azide in place of ribose 2'OH
分子名称: 1,2-ETHANEDIOL, 9-[2-azido-2-deoxy-5-O-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)-beta-D-arabinofuranosyl]-9H-purin-6-amine, Bifunctional ligase/repressor BirA
著者De la Mora-Rey, T, Finzel, B.C.
登録日2015-01-24
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.30010319 Å)
主引用文献Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.
J.Med.Chem., 58, 2015
4XTY
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Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor 63 with Fluorine in place of 2'OH
分子名称: 2',5'-dideoxy-2'-fluoro-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine, Bifunctional ligase/repressor BirA
著者De la Mora-Rey, T, Finzel, B.C.
登録日2015-01-24
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.80002666 Å)
主引用文献Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.
J.Med.Chem., 58, 2015
4XU2
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Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor 87 with a 3'deoxy ribose
分子名称: 3',5'-dideoxy-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine, Bifunctional ligase/repressor BirA
著者De la Mora-Rey, T, Finzel, B.C.
登録日2015-01-24
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8500284 Å)
主引用文献Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.
J.Med.Chem., 58, 2015

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