PDB: 6543 件ウェブページステータス検索Chemie searchBIRD

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5F35	Structure of quinolinate synthase in complex with citrate 分子名称: CITRATE ANION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2015-12-02 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product. J.Am.Chem.Soc., 138, 2016
5F3D	Structure of quinolinate synthase in complex with reaction intermediate W 分子名称: 2-IMINO,3-CARBOXY,5-OXO,6-HYDROXY HEXANOIC ACID, IRON/SULFUR CLUSTER, Quinolinate synthase A, ... 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2015-12-02 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product. J.Am.Chem.Soc., 138, 2016
2WPW	Tandem GNAT protein from the clavulanic acid biosynthesis pathway (without AcCoA) 分子名称: ACETYL COENZYME *A, ORF14 著者 Iqbal, A, Arunlanantham, H, McDonough, M.A, Chowdhury, R, Clifton, I.J. 登録日 2009-08-11 公開日 2009-12-29 最終更新日 2018-03-28 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway. Proteins, 78, 2010
2WL6	BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. THE N316H-H348N MUTANT. 分子名称: ACETYL-COA ACETYLTRANSFERASE 著者 Merilainen, G, Poikela, V, Kursula, P, Wierenga, R.K. 登録日 2009-06-22 公開日 2009-11-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation. Biochemistry, 48, 2009
5F33	Structure of quinolinate synthase in complex with phosphoglycolohydroxamate 分子名称: IRON/SULFUR CLUSTER, PHOSPHOGLYCOLOHYDROXAMIC ACID, Quinolinate synthase A, ... 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2015-12-02 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product. J.Am.Chem.Soc., 138, 2016
3IQI	Structure of O-Acetylserine Sulfhydrylase in Complex with Peptide MNENI 分子名称: Cysteine synthase, MNENI 著者 Roderick, S.L. 登録日 2009-08-20 公開日 2009-11-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Design of o-acetylserine sulfhydrylase inhibitors by mimicking nature. J.Med.Chem., 53, 2010
6TDH	Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1 in complex with compound 1 分子名称: 3-(2-chlorophenyl)-4~{H}-1,2,4-triazole, ACETYL COENZYME *A, Glucosamine 6-phosphate N-acetyltransferase 著者 Raimi, O.G, Stanley, M, Lockhart, D. 登録日 2019-11-08 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Targeting a critical step in fungal hexosamine biosynthesis. J.Biol.Chem., 295, 2020
6PUX	Homoserine transacetylase MetX from Mycobacterium tuberculosis 分子名称: CHLORIDE ION, GLYCEROL, Homoserine O-acetyltransferase, ... 著者 Chaton, C.T, Korotkov, K.V. 登録日 2019-07-18 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site. Sci Rep, 9, 2019
5J7W	Enterococcus faecalis thymidylate synthase complex with methotrexate 分子名称: METHOTREXATE, SULFATE ION, Thymidylate synthase 著者 Mangani, S, Pozzi, C. 登録日 2016-04-07 公開日 2016-09-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors. Eur.J.Med.Chem., 123, 2016
3O6C	Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni 分子名称: PHOSPHATE ION, Pyridoxine 5'-phosphate synthase 著者 Osipiuk, J, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-07-28 公開日 2010-08-11 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni. To be Published
4E7B	E. cloacae MurA in complex with UDP-glucose 分子名称: 1,2-ETHANEDIOL, ACETATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ... 著者 Zhu, J.-Y, Yang, Y, Schonbrunn, E. 登録日 2012-03-16 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Open-close transition of MurA To be Published
5ZZU	Crystal structure of the C-terminal periplasmic domain of EcEptC from Escherichia coli- complex with Zn 分子名称: Phosphoethanolamine transferase EptC, ZINC ION 著者 Zhao, Y.Q, Cheng, W, Gu, Y.J. 登録日 2018-06-04 公開日 2019-06-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and mechanistic insights into polymyxin resistance mediated by EptC originating from Escherichia coli To Be Published
4E8O	Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-Ih from Acinetobacter baumannii 分子名称: Aac(6')-Ih protein, CHLORIDE ION 著者 Stogios, P.J, Minasov, G, Dong, A, Evdokimova, E, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-03-20 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.138 Å) 主引用文献 Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes. ACS Infect Dis., 3, 2017
6A2N	Crystal structure of quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum DHFR-TS complexed with BT2, NADPH, and dUMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... 著者 Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y. 登録日 2018-06-12 公開日 2019-04-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance. ACS Med Chem Lett, 9, 2018
3ID0	Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 3-Fluoro-1-(2-hydroxy-2,2-bisphosphono-ethyl)pyridinium 分子名称: 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... 著者 Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. 登録日 2009-07-19 公開日 2010-02-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. Proteins, 78, 2010
5IX3	Crystal structure of N-acetyltransferase from Staphylococcus aureus. 分子名称: Diamine N-acetyltransferase 著者 Srivastava, P, Khandokar, Y, Forwood, J. 登録日 2016-03-23 公開日 2017-04-05 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Crystal structure of N-acetyltransferase from Staphylococcus aureus. To Be Published
7XAY	Crystal structure of Hat1-Hat2-Asf1-H3-H4 分子名称: COENZYME A, Histone H3, Histone H4, ... 著者 Yue, Y, Yang, W.S, Xu, R.M. 登録日 2022-03-19 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Topography of histone H3-H4 interaction with the Hat1-Hat2 acetyltransferase complex. Genes Dev., 36, 2022
7L4L	Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabF, and C8-crypto Acyl Carrier Protein, AcpP 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Acyl carrier protein, SODIUM ION, ... 著者 Mindrebo, J.T, Chen, A, Kim, W.E, Burkart, M.D, Noel, J.P. 登録日 2020-12-19 公開日 2021-09-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure and Mechanistic Analyses of the Gating Mechanism of Elongating Ketosynthases Acs Catalysis, 11, 2021
2V07	Structure of the Arabidopsis thaliana cytochrome c6A V52Q variant 分子名称: CYTOCHROME C6, HEME C 著者 Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J. 登録日 2007-05-09 公開日 2007-07-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Modulation of heme redox potential in the cytochrome c6 family. J. Am. Chem. Soc., 129, 2007
5F0V	X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution 分子名称: 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase 著者 Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N. 登録日 2015-11-28 公開日 2016-07-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution. Acta Crystallogr.,Sect.F, 72, 2016
5F46	Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample, apoenzyme form 分子名称: CHLORIDE ION, aminoglycoside acetyltransferase meta-AAC0020 著者 Xu, Z, Skarina, T, Stogios, P.J, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2015-12-03 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes. ACS Infect Dis, 3, 2017
3I8P	Crystal structure of E. coli FabF(C163A) in complex with Platensimycin A1 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Platensimycin A1 著者 Soisson, S.M, Parthsarathy, G. 登録日 2009-07-09 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis. Bioorg.Med.Chem.Lett., 19, 2009
3NVS	1.02 Angstrom resolution crystal structure of 3-phosphoshikimate 1-carboxyvinyltransferase from Vibrio cholerae in complex with shikimate-3-phosphate (partially photolyzed) and glyphosate 分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Minasov, G, Light, S.H, Halavaty, A, Shuvalova, G, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-07-08 公開日 2010-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.021 Å) 主引用文献 1.02 Angstrom Resolution Crystal Structure of 3-Phosphoshikimate 1-Carboxyvinyltransferase from Vibrio cholerae in complex with Shikimate-3-Phosphate (Partially Photolyzed) and Glyphosate TO BE PUBLISHED
5JKJ	Crystal structure of esterase E22 L374D mutant 分子名称: Esterase E22 著者 Zhang, Y, Wang, P, Yao, Q. 登録日 2016-04-26 公開日 2017-04-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis for substrate recognition and catalysis of a novel esterase E22 with a homoserine transacetylase-like fold To Be Published
5F48	Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample in complex with coenzyme A 分子名称: CHLORIDE ION, COENZYME A, MAGNESIUM ION, ... 著者 Xu, Z, Skarina, T, Stogios, P.J, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2015-12-03 公開日 2015-12-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes. ACS Infect Dis, 3, 2017

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