2CKX
 
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6GMP
 | | CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF TBPAR42 | | 分子名称: | PARVULIN 42 | | 著者 | Hoenig, D, Rute, A, Hofmann, E, Bayer, P, Gasper, R. | | 登録日 | 2018-05-28 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural Analysis of the 42 kDa Parvulin ofTrypanosoma brucei.
Biomolecules, 9, 2019
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1H3O
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4OY2
 | | Crystal structure of TAF1-TAF7, a TFIID subcomplex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7, ... | | 著者 | Bhattacharya, S, Lou, X, Rajashankar, K, Jacobson, R.H, Webb, P. | | 登録日 | 2014-02-10 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.
Proc.Natl.Acad.Sci.USA, 111, 2014
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8XVG
 | | Structure of human NuA4/TIP60 complex | | 分子名称: | ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 6A, ... | | 著者 | Chen, K, Wang, L, Yu, Z, Yu, J, Ren, Y, Wang, Q, Xu, Y. | | 登録日 | 2024-01-15 | | 公開日 | 2024-07-24 | | 最終更新日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | Structure of the human TIP60 complex.
Nat Commun, 15, 2024
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8XVT
 | | The core subcomplex of human NuA4/TIP60 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | 著者 | Chen, K, Wang, L, Yu, Z, Yu, J, Ren, Y, Wang, Q, Xu, Y. | | 登録日 | 2024-01-15 | | 公開日 | 2024-07-24 | | 最終更新日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human TIP60 complex.
Nat Commun, 15, 2024
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7T36
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7T2I
 | | Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588 | | 分子名称: | 1,2-ETHANEDIOL, 4-(6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-[(3R)-3-methylmorpholin-4-yl]pyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridine, DIMETHYL SULFOXIDE, ... | | 著者 | Karim, M.R, Schonbrunn, E. | | 登録日 | 2021-12-04 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-588
To Be Published
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5OAF
 | | Human Rvb1/Rvb2 heterohexamer in INO80 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | | 著者 | Aramayo, R.J, Bythell-Douglas, R, Ayala, R, Willhoft, O, Wigley, D, Zhang, X. | | 登録日 | 2017-06-21 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | | 主引用文献 | Cryo-EM structures of the human INO80 chromatin-remodeling complex.
Nat. Struct. Mol. Biol., 25, 2018
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7UHE
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3GAY
 | | Structure of Giardia fructose-1,6-biphosphate aldolase in complex with tagatose-1,6-biphosphate | | 分子名称: | 1,6-di-O-phosphono-D-tagatose, Fructose-bisphosphate aldolase, ZINC ION | | 著者 | Galkin, A, Herzberg, O. | | 登録日 | 2009-02-18 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase.
Biochemistry, 48, 2009
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3GAK
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3GB6
 | | Structure of Giardia fructose-1,6-biphosphate aldolase D83A mutant in complex with fructose-1,6-bisphosphate | | 分子名称: | 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase, ZINC ION | | 著者 | Galkin, A, Herzberg, O. | | 登録日 | 2009-02-18 | | 公開日 | 2009-03-31 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase.
Biochemistry, 48, 2009
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9EMC
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9EMA
 | | RUVBL1/2 in complex with ATP and CB-6644 inhibitor | | 分子名称: | 5-chloranyl-2-ethoxy-4-fluoranyl-~{N}-[4-[[3-(methoxymethyl)-1-oxidanylidene-6,7-dihydro-5~{H}-pyrazolo[1,2-a][1,2]benzodiazepin-2-yl]amino]-2,2-dimethyl-4-oxidanylidene-butyl]benzamide, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Lopez-Perrote, A, Llorca, O, Garcia-Martin, C. | | 登録日 | 2024-03-07 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Mechanism of allosteric inhibition of RUVBL1-RUVBL2 by the small-molecule CB-6644
Cell Rep Phys Sci, 2024
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7AHO
 | | RUVBL1-RUVBL2 heterohexameric ring after binding of RNA helicase DHX34 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | | 著者 | Lopez-Perrote, A, Rodriguez, C.F, Llorca, O. | | 登録日 | 2020-09-25 | | 公開日 | 2020-11-25 | | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | | 主引用文献 | Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM.
Elife, 9, 2020
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3UV5
 | | Crystal Structure of the tandem bromodomains of human Transcription initiation factor TFIID subunit 1 (TAF1) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcription initiation factor TFIID subunit 1 | | 著者 | Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-11-29 | | 公開日 | 2012-01-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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7OLE
 | | Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ... | | 著者 | Pal, M, Llorca, O, Pearl, L. | | 登録日 | 2021-05-19 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-10-06 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone.
Cell Rep, 36, 2021
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6K0R
 | | Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin | | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Zhang, W, Chen, L, Li, W, Ju, D, Huang, N, Zhang, E. | | 登録日 | 2019-05-07 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals.
Sci Transl Med, 12, 2020
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7P6X
 | | Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | | 著者 | Llorca, O, Serna, M, Fernandez-Leiro, R. | | 登録日 | 2021-07-18 | | 公開日 | 2021-12-15 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.
Nucleic Acids Res., 50, 2022
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7ZI4
 | | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Vance, N.R, Ayala, R, Willhoft, O, Tvardovskiy, A, McCormack, E.A, Bartke, T, Zhang, X, Wigley, D.B. | | 登録日 | 2022-04-07 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
To Be Published
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3RJ1
 | | Architecture of the Mediator Head module | | 分子名称: | Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... | | 著者 | Imasaki, T, Calero, G, Cai, G, Tsai, K.L, Yamada, K, Cardelli, F, Erdjument-Bromage, H, Tempst, P, Berger, I, Kornberg, G.L, Asturias, F.J, Kornberg, R.D, Takagi, Y. | | 登録日 | 2011-04-14 | | 公開日 | 2011-07-27 | | 最終更新日 | 2017-08-02 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Architecture of the Mediator head module.
Nature, 475, 2011
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2XSZ
 | | The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, RUVB-LIKE 1, RUVB-LIKE 2 | | 著者 | Gorynia, S, Bandeiras, T.M, Matias, P.M, Pinho, F.G, McVey, C.E, Vonrhein, C, Svergun, D.I, Round, A, Donner, P, Carrondo, M.A. | | 登録日 | 2010-10-01 | | 公開日 | 2011-10-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and Functional Insights Into a Dodecameric Molecular Machine - the Ruvbl1/Ruvbl2 Complex.
J.Struct.Biol., 176, 2011
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8CVT
 | | Human 19S-20S proteasome, state SD2 | | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... | | 著者 | Zhao, J. | | 登録日 | 2022-05-18 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8OR3
 | | CAND1-CUL1-RBX1-SKP1-SKP2-DCNL1 | | 分子名称: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, DCN1-like protein 1, ... | | 著者 | Shaaban, M, Clapperton, J.A, Ding, S, Maeots, M.E, Enchev, R.I. | | 登録日 | 2023-04-13 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange.
Mol.Cell, 83, 2023
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