7KSG
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![BU of 7ksg by Molmil](/molmil-images/mine/7ksg) | SARS-CoV-2 spike in complex with nanobodies E | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 glycoprotein, Spike glycoprotein | 著者 | Hallberg, B.M, Das, H. | 登録日 | 2020-11-22 | 公開日 | 2021-01-20 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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7KHV
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![BU of 7khv by Molmil](/molmil-images/mine/7khv) | CpOGA IN COMPLEX WITH LIGAND 54 | 分子名称: | CALCIUM ION, CHLORIDE ION, N-(5-{[6-(5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-2,6-diazaspiro[3.4]octan-2-yl]methyl}-1,3-thiazol-2-yl)acetamide, ... | 著者 | Shaffer, P.L. | 登録日 | 2020-10-22 | 公開日 | 2020-12-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders. J.Med.Chem., 63, 2020
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7KNB
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![BU of 7knb by Molmil](/molmil-images/mine/7knb) | Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 7.4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Gorman, J, Kwong, P.D, Shapiro, L. | 登録日 | 2020-11-04 | 公開日 | 2020-12-09 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. Cell Host Microbe, 28, 2020
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7L6B
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7KNH
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![BU of 7knh by Molmil](/molmil-images/mine/7knh) | Cryo-EM Structure of Double ACE2-Bound SARS-CoV-2 Trimer Spike at pH 5.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L. | 登録日 | 2020-11-04 | 公開日 | 2020-12-16 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. Cell Host Microbe, 28, 2020
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7KJ3
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![BU of 7kj3 by Molmil](/molmil-images/mine/7kj3) | SARS-CoV-2 Spike Glycoprotein with two ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. | 登録日 | 2020-10-25 | 公開日 | 2020-11-11 | 最終更新日 | 2021-02-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat.Struct.Mol.Biol., 28, 2021
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7KZM
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![BU of 7kzm by Molmil](/molmil-images/mine/7kzm) | Outer dynein arm bound to doublet microtubules from C. reinhardtii | 分子名称: | DC1, DC2, Dynein 11 kDa light chain, ... | 著者 | Walton, T, Wu, H, Brown, A.B. | 登録日 | 2020-12-10 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Structure of a microtubule-bound axonemal dynein. Nat Commun, 12, 2021
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4N2R
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![BU of 4n2r by Molmil](/molmil-images/mine/4n2r) | Crystal Structure of the alpha-L-arabinofuranosidase UmAbf62A from Ustilago maydis in complex with L-arabinofuranose | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, alpha-L-arabinofuranose, ... | 著者 | Siguier, B, Dumon, C, Mourey, L, Tranier, S. | 登録日 | 2013-10-06 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies. J.Biol.Chem., 289, 2014
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7KZO
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![BU of 7kzo by Molmil](/molmil-images/mine/7kzo) | Outer dynein arm docking complex bound to doublet microtubules from C. reinhardtii | 分子名称: | Dynein gamma chain, flagellar outer arm, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Walton, T, Wu, H, Brown, A.B. | 登録日 | 2020-12-10 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of a microtubule-bound axonemal dynein. Nat Commun, 12, 2021
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6LGV
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![BU of 6lgv by Molmil](/molmil-images/mine/6lgv) | Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with citrate | 分子名称: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Transporter, ... | 著者 | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | 登録日 | 2019-12-06 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | 主引用文献 | Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii. Acta Crystallogr D Struct Biol, 77, 2021
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7KJ5
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![BU of 7kj5 by Molmil](/molmil-images/mine/7kj5) | SARS-CoV-2 Spike Glycoprotein, prefusion with one RBD up conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. | 登録日 | 2020-10-25 | 公開日 | 2020-11-11 | 最終更新日 | 2021-02-24 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat.Struct.Mol.Biol., 28, 2021
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7KKK
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![BU of 7kkk by Molmil](/molmil-images/mine/7kkk) | SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Schoof, M.S, Faust, B.F, Saunders, R.A, Sangwan, S, Rezelj, V, Hoppe, N, Boone, M, Billesboelle, C.B, Puchades, C, Azumaya, C.M, Kratochvil, H.T, Zimanyi, M, Desphande, I, Liang, J, Dickinson, S, Nguyen, H.C, Chio, C.M, Merz, G.E, Thompson, M.C, Diwanji, D, Schaefer, K, Anand, A.A, Dobzinski, N, Zha, B.S, Simoneau, C.R, Leon, K, White, K.M, Chio, U.S, Gupta, M, Jin, M, Li, F, Liu, Y, Zhang, K, Bulkley, D, Sun, M, Smith, A.M, Rizo, A.N, Moss, F, Brilot, A.F, Pourmal, S, Trenker, R, Pospiech, T, Gupta, S, Barsi-Rhyne, B, Belyy, V, Barile-Hill, A.W, Nock, S, Liu, Y, Krogan, N.J, Ralston, C.Y, Swaney, D.L, Garcia-Sastre, A, Ott, M, Vignuzzi, M, Walter, P, Manglik, A, QCRG Structural Biology Consortium | 登録日 | 2020-10-27 | 公開日 | 2020-11-11 | 最終更新日 | 2021-04-21 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science, 370, 2020
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4NB6
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![BU of 4nb6 by Molmil](/molmil-images/mine/4nb6) | Crystal structure of the ligand binding domain of RORC with T0901317 | 分子名称: | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, Nuclear receptor ROR-gamma | 著者 | Hymowitz, S.G, Boenig-de Leon, G. | 登録日 | 2013-10-22 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc. Bioorg.Med.Chem.Lett., 23, 2013
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7L6A
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7L6E
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4MQ4
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![BU of 4mq4 by Molmil](/molmil-images/mine/4mq4) | Crystal Structure of hPNMT in Complex with bisubstrate inhibitor N-(3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)propyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-S-(3-{[(3R)-1,2,3,4-tetrahydroisoquinolin-3-ylcarbonyl]amino}propyl)-5'-thioadenosine, Phenylethanolamine N-methyltransferase | 著者 | Bart, A.G, Scott, E.E. | 登録日 | 2013-09-15 | 公開日 | 2014-10-15 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2042 Å) | 主引用文献 | To be Published To be Published
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6L7Z
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![BU of 6l7z by Molmil](/molmil-images/mine/6l7z) | Solution NMR structure of the N-terminal immunoglobulin variable domain of BTNL2 | 分子名称: | Butyrophilin-like protein 2 | 著者 | Basak, A.J, Lee, W, Samanta, D, De, S. | 登録日 | 2019-11-03 | 公開日 | 2020-10-14 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors. J.Mol.Biol., 432, 2020
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7KMV
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![BU of 7kmv by Molmil](/molmil-images/mine/7kmv) | Structure of Malaysian Banana Lectin F84T | 分子名称: | Jacalin-type lectin domain-containing protein, SULFATE ION | 著者 | Meagher, J.L, Stuckey, J.A. | 登録日 | 2020-11-03 | 公開日 | 2021-01-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Targeted disruption of pi-pi stacking in Malaysian banana lectin reduces mitogenicity while preserving antiviral activity. Sci Rep, 11, 2021
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7KQ6
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7L06
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![BU of 7l06 by Molmil](/molmil-images/mine/7l06) | Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to two copies of domain-swapped antibody 2G12 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ... | 著者 | Manne, K, Henderson, R, Acharya, P. | 登録日 | 2020-12-11 | 公開日 | 2020-12-30 | 最終更新日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
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7KXK
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7L6F
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![BU of 7l6f by Molmil](/molmil-images/mine/7l6f) | The empty AAV11 capsid | 分子名称: | Capsid protein | 著者 | Mietzsch, M, Agbandje-McKenna, M. | 登録日 | 2020-12-23 | 公開日 | 2021-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Completion of the AAV Structural Atlas: Serotype Capsid Structures Reveals Clade-Specific Features. Viruses, 13, 2021
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7L5U
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![BU of 7l5u by Molmil](/molmil-images/mine/7l5u) | The full AAV7 capsid | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid protein | 著者 | Mietzsch, M, Agbandje-McKenna, M. | 登録日 | 2020-12-22 | 公開日 | 2021-02-03 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Completion of the AAV Structural Atlas: Serotype Capsid Structures Reveals Clade-Specific Features. Viruses, 13, 2021
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7KJ2
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![BU of 7kj2 by Molmil](/molmil-images/mine/7kj2) | SARS-CoV-2 Spike Glycoprotein with one ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. | 登録日 | 2020-10-25 | 公開日 | 2020-11-11 | 最終更新日 | 2021-02-24 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat.Struct.Mol.Biol., 28, 2021
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7KOD
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![BU of 7kod by Molmil](/molmil-images/mine/7kod) | Cryo-EM structure of heavy chain mouse apoferritin | 分子名称: | Ferritin heavy chain | 著者 | Sun, M, Azumaya, C, Tse, E, Frost, A, Southworth, D, Verba, K.A, Cheng, Y, Agard, D.A. | 登録日 | 2020-11-08 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (1.655 Å) | 主引用文献 | Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM. J.Struct.Biol., 213, 2021
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