5UWN
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![BU of 5uwn by Molmil](/molmil-images/mine/5uwn) | Matrix metalloproteinase-13 complexed with selective inhibitor compound 10d | 分子名称: | CALCIUM ION, Collagenase 3, N-(2-aminoethyl)-4'-(((4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)methyl)-[1,1'-biphenyl]-4-sulfonami de, ... | 著者 | Taylor, A.B, Cao, X, Hart, P.J. | 登録日 | 2017-02-21 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. J. Med. Chem., 60, 2017
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7X7M
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![BU of 7x7m by Molmil](/molmil-images/mine/7x7m) | Lumazine Synthase from Aquifex aeolicus | 分子名称: | 6,7-dimethyl-8-ribityllumazine synthase | 著者 | Sobhy, M.A, Hamdan, S.M. | 登録日 | 2022-03-09 | 公開日 | 2022-10-12 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | 主引用文献 | Cryo-electron structures of the extreme thermostable enzymes Sulfur Oxygenase Reductase and Lumazine Synthase. Plos One, 17, 2022
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5UYL
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![BU of 5uyl by Molmil](/molmil-images/mine/5uyl) | 70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | 登録日 | 2017-02-24 | 公開日 | 2017-06-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Ensemble cryo-EM elucidates the mechanism of translation fidelity. Nature, 546, 2017
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6TMG
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![BU of 6tmg by Molmil](/molmil-images/mine/6tmg) | Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, membrane region model | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ATPTG1, ... | 著者 | Muhleip, A, Kock Flygaard, R, Amunts, A. | 登録日 | 2019-12-04 | 公開日 | 2020-12-16 | 最終更新日 | 2021-01-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria. Nat Commun, 12, 2021
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6TPQ
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![BU of 6tpq by Molmil](/molmil-images/mine/6tpq) | RNase M5 bound to 50S ribosome with precursor 5S rRNA | 分子名称: | 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C. | 登録日 | 2019-12-13 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs. Mol.Cell, 80, 2020
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6TU6
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![BU of 6tu6 by Molmil](/molmil-images/mine/6tu6) | |
5VCB
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![BU of 5vcb by Molmil](/molmil-images/mine/5vcb) | |
5UK4
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![BU of 5uk4 by Molmil](/molmil-images/mine/5uk4) | VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307 | 分子名称: | Anti-vesicular stomatitis virus N VHH, Nucleoprotein, RNA (45-MER) | 著者 | Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U. | 登録日 | 2017-01-19 | 公開日 | 2017-04-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.204 Å) | 主引用文献 | Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication. EMBO Rep., 18, 2017
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4ZP3
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![BU of 4zp3 by Molmil](/molmil-images/mine/4zp3) | AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA | 分子名称: | A-kinase anchor protein 7 isoforms alpha and beta, CADMIUM ION, cAMP-dependent protein kinase type II-alpha regulatory subunit | 著者 | Goetz, F, Roske, Y, Faelber, K, Zuehlke, K, Autenrieth, K, Kreuchwig, A, Krause, G, Herberg, F.W, Daumke, O, Heinemann, U, Klussmann, E. | 登録日 | 2015-05-07 | 公開日 | 2016-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | AKAP18:PKA-RII alpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA. Biochem.J., 473, 2016
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6TRC
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![BU of 6trc by Molmil](/molmil-images/mine/6trc) | Cryo- EM structure of the Thermosynechococcus elongatus photosystem I in the presence of cytochrome c6 | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Koelsch, A, Radon, C, Baumert, A, Buerger, J, Mielke, T, Lisdat, F, Zouni, A, Wendler, P. | 登録日 | 2019-12-18 | 公開日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Current limits of structural biology: The transient interaction between cytochrome c6 and photosystem I Curr.Opin.Struct.Biol., 2, 2020
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6TUG
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5UOC
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![BU of 5uoc by Molmil](/molmil-images/mine/5uoc) | Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2S)-2-(methylamino)propyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... | 著者 | Chreifi, G, Li, H, Poulos, T.L. | 登録日 | 2017-01-31 | 公開日 | 2017-05-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
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7XBZ
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![BU of 7xbz by Molmil](/molmil-images/mine/7xbz) | Crystal structure of Staphylococcus aureus ClpP in complex with R-ZG197 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (6S,9aS)-6-[(2S)-butan-2-yl]-8-[(1R)-1-naphthalen-1-ylethyl]-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, ... | 著者 | Wei, B.Y, Gan, J.H, Yang, C.-G. | 登録日 | 2022-03-22 | 公開日 | 2022-11-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP. Nat Commun, 13, 2022
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5UR9
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![BU of 5ur9 by Molmil](/molmil-images/mine/5ur9) | Enantiomer-Specific Binding of the Potent Antinociceptive Agent SBFI-26 to Anandamide transporters FABP5 | 分子名称: | (1S,2S,3S,4S)-3-{[(naphthalen-1-yl)oxy]carbonyl}-2,4-diphenylcyclobutane-1-carboxylic acid, Fatty acid-binding protein, epidermal, ... | 著者 | Hsu, H.-C, Li, H. | 登録日 | 2017-02-09 | 公開日 | 2017-08-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.19800353 Å) | 主引用文献 | The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites. Biochemistry, 56, 2017
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5US6
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![BU of 5us6 by Molmil](/molmil-images/mine/5us6) | Structure of Dihydrodipicolinate Reductase from Vibrio vulnificus Bound to NADH and 2,6 Pyridine Dicarboxylic Acid with Intact Polyhistidine Tag | 分子名称: | 4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... | 著者 | Mank, N.M, Arnette, A.K, Chruszcz, M. | 登録日 | 2017-02-13 | 公開日 | 2018-02-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus. Biochim Biophys Acta Gen Subj, 1865, 2021
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5VBF
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6JTD
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![BU of 6jtd by Molmil](/molmil-images/mine/6jtd) | Crystal structure of TcCGT1 in complex with UDP | 分子名称: | 1,2-ETHANEDIOL, C-glycosyltransferase, URIDINE-5'-DIPHOSPHATE | 著者 | Zhao, P, Yun, C.H. | 登録日 | 2019-04-10 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular and Structural Characterization of a Promiscuous C-Glycosyltransferase from Trollius chinensis. Angew.Chem.Int.Ed.Engl., 58, 2019
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7XAM
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6SB5
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6SGC
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![BU of 6sgc by Molmil](/molmil-images/mine/6sgc) | Rabbit 80S ribosome stalled on a poly(A) tail | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2019-08-03 | 公開日 | 2019-12-04 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of ribosome stalling during translation of a poly(A) tail. Nat.Struct.Mol.Biol., 26, 2019
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5VZ2
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6HBL
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![BU of 6hbl by Molmil](/molmil-images/mine/6hbl) | Echovirus 18 Open particle without three pentamers | 分子名称: | Echovirus 18 capsid protein 1, Echovirus 18 capsid protein 2, Echovirus 18 capsid protein 3 | 著者 | Buchta, D, Fuzik, T, Hrebik, D, Levdansky, Y, Moravcova, J, Plevka, P. | 登録日 | 2018-08-10 | 公開日 | 2019-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Enterovirus particles expel capsid pentamers to enable genome release. Nat Commun, 10, 2019
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6SPG
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![BU of 6spg by Molmil](/molmil-images/mine/6spg) | Pseudomonas aeruginosa 70s ribosome from a clinical isolate | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A. | 登録日 | 2019-09-01 | 公開日 | 2019-10-16 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | 主引用文献 | Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate. Proc.Natl.Acad.Sci.USA, 116, 2019
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6HCM
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![BU of 6hcm by Molmil](/molmil-images/mine/6hcm) | Structure of the rabbit collided di-ribosome (stalled monosome) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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6HAY
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![BU of 6hay by Molmil](/molmil-images/mine/6hay) | Crystal structure of PROTAC 1 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB | 分子名称: | (2~{S},4~{R})-~{N}-[[2-[2-[2-[2-[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]ethoxy]ethoxy]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Roy, M, Bader, G, Diers, E, Trainor, N, Farnaby, W, Ciulli, A. | 登録日 | 2018-08-09 | 公開日 | 2019-06-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat.Chem.Biol., 15, 2019
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