PDB: 47902 件ウェブページステータス検索Chemie searchBIRD

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3W6E	Crystal structure of catalytic domain of chitinase from Ralstonia sp. A-471 (E162Q) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Lysozyme-like chitinolytic enzyme 著者 Arimori, T, Kawamoto, N, Okazaki, N, Nakazawa, M, Miyatake, K, Fukamizo, T, Ueda, M, Tamada, T. 登録日 2013-02-14 公開日 2013-05-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structures of the Catalytic Domain of a Novel Glycohydrolase Family 23 Chitinase from Ralstonia sp. A-471 Reveals a Unique Arrangement of the Catalytic Residues for Inverting Chitin Hydrolysis J.Biol.Chem., 288, 2013
7P4S	BROMODOMAIN OF HUMAN TAF1 (2) WITH naphthyridinone compound 分子名称: 8-[[1-(3-azanylpropyl)piperidin-4-yl]amino]-5-[5-(hydroxymethyl)pyridin-3-yl]-3-methyl-1~{H}-1,7-naphthyridin-2-one, Isoform 2a of Transcription initiation factor TFIID subunit 1 著者 Chung, C. 登録日 2021-07-13 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Optimization of Naphthyridones into Selective TATA-Binding Protein Associated Factor 1 (TAF1) Bromodomain Inhibitors. Acs Med.Chem.Lett., 12, 2021
8TOP	Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP glycoprotein gp41, ... 著者 Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D. 登録日 2023-08-03 公開日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide To Be Published
7PA4	Crystal structure of CD73 in complex with CMP in the open form 分子名称: 5'-nucleotidase, CALCIUM ION, CHLORIDE ION, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-07-28 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
6GTD	Transient state structure of CRISPR-Cpf1 (Cas12a) I2 conformation 分子名称: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*GP*T)-3'), DNA (5'-D(P*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ... 著者 Montoya, G, Mesa, P. 登録日 2018-06-18 公開日 2018-12-19 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. Cell, 175, 2018
3W9R	Crystal structure of the high-affinity abscisic acid receptor PYL9/RCAR9 bound to ABA 分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL9, HEXAETHYLENE GLYCOL 著者 Nakagawa, M, Hirano, Y, Kagiyama, M, Shibata, N, Hakoshima, T. 登録日 2013-04-13 公開日 2014-04-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanism of high-affinity abscisic acid binding to PYL9/RCAR1. Genes Cells, 19, 2014
7OWY	Crystal structure of human mitochondrial ferritin (hMTF) Fe(II)-loaded for 3 minutes showing a peroxide anion as bridging species of iron ions in the ferroxidase site 分子名称: CHLORIDE ION, FE (II) ION, Ferritin, ... 著者 Pozzi, C, Ciambellotti, S, Tassone, G, Turano, P, Mangani, S. 登録日 2021-06-21 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin. Chemistry, 27, 2021
7PBB	Crystal structure of CD73 in complex with caffeine in the open form 分子名称: 5'-nucleotidase, CAFFEINE, CALCIUM ION, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-08-01 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
4LF2	Hexameric Form II RuBisCO from Rhodopseudomonas palustris, activated and complexed with sulfate and magnesium 分子名称: CARBONATE ION, MAGNESIUM ION, Ribulose bisphosphate carboxylase, ... 著者 Chan, S, Satagopan, S, Sawaya, M.R, Eisenberg, D, Tabita, F.R, Perry, L.J. 登録日 2013-06-26 公開日 2014-06-25 最終更新日 2016-07-20 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Structure-function studies with the unique hexameric form II ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from Rhodopseudomonas palustris. J.Biol.Chem., 289, 2014
7Q57	Single Particle Cryo-EM structure of photosynthetic A10B10 glyceraldehyde-3-phospahte dehydrogenase from Spinacia oleracea. 分子名称: Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic,Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic, ... 著者 Marotta, R, Fermani, S, Sparla, F, Trost, P, Del Giudice, A. 登録日 2021-11-02 公開日 2022-11-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (13 Å) 主引用文献 Unravelling the regulation pathway of photosynthetic AB-GAPDH. Acta Crystallogr D Struct Biol, 78, 2022
7OKQ	Cryo-EM Structure of the DDB1-DCAF1-CUL4A-RBX1 Complex 分子名称: Cullin-4A, DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, ... 著者 Mohamed, W.I, Schenk, A.D, Kempf, G, Cavadini, S, Thoma, N.H. 登録日 2021-05-18 公開日 2021-10-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (8.4 Å) 主引用文献 The CRL4 DCAF1 cullin-RING ubiquitin ligase is activated following a switch in oligomerization state. Embo J., 40, 2021
7PBA	Crystal structure of CD73 in complex with IMP in the open form 分子名称: 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-08-01 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
6GWK	The crystal structure of Hfq from Caulobacter crescentus 分子名称: RNA-binding protein Hfq 著者 Santiago-Frangos, A, Frohlich, K.S, Jeliazkov, J.R, Gray, J.R, Luisi, B.F, Woodson, S.A, Hardwick, S.W. 登録日 2018-06-25 公開日 2019-05-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Caulobacter crescentusHfq structure reveals a conserved mechanism of RNA annealing regulation. Proc.Natl.Acad.Sci.USA, 116, 2019
6E3R	Structure of human DNA polymerase beta complexed with 8OA as the template base in a 1-nucleotide gapped DNA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-14 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
7P9N	Crystal structure of CD73 in complex with AMP in the open form 分子名称: 5'-nucleotidase, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-07-27 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
6GWV	Molybdenum storage protein without polymolybdate clusters and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Molybdenum storage protein subunit alpha, ... 著者 Ermler, U, Poppe, J, Bruenle, S. 登録日 2018-06-26 公開日 2018-11-07 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Molybdenum Storage Protein: A soluble ATP hydrolysis-dependent molybdate pump. FEBS J., 285, 2018
7OQP	Crystal structure of the human METTL3-METTL14 complex with compound UOZ113 分子名称: ACETATE ION, N-[[(3R)-1-[6-(1-benzothiophen-4-ylmethylamino)pyrimidin-4-yl]-3-oxidanyl-piperidin-3-yl]methyl]-2-oxidanyl-4-[[(3S)-3-propan-2-yl-2-azaspiro[3.3]heptan-2-yl]methyl]benzamide, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-06-03 公開日 2021-10-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
6GW2	GII.10 human norovirus protruding domain in complex with taurochenodeoxycholate (TCDCA) 分子名称: 1,2-ETHANEDIOL, Capsid protein, TAUROCHENODEOXYCHOLIC ACID 著者 Kilic, T, Hansman, G.S. 登録日 2018-06-21 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Basis for Human Norovirus Capsid Binding to Bile Acids. J. Virol., 93, 2019
6E3V	Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable TTP 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-07-15 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141, 2019
4L9I	Bovine G Protein Coupled Receptor Kinase 1 in Complex with Paroxetine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Paroxetine, ... 著者 Homan, K.T, Tesmer, J.J.G. 登録日 2013-06-18 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog. Mol.Pharmacol., 85, 2014
8TOZ	Class III PreQ1 riboswitch double mutant U8C/A85G 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, Class-III preQ1 riboswitch 著者 Srivastava, Y, Jenkins, J.L, Wedekind, J.E. 登録日 2023-08-04 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 New insights into Class III PreQ1 metabolite binding To Be Published
6GYJ	Mouse thymidylate synthase crystal soaked in phenolphthalein 分子名称: 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, DIMETHYL SULFOXIDE, SULFATE ION, ... 著者 Maj, P, Jarmula, A, Wilk, P, Weiss, M.S, Rode, W. 登録日 2018-06-30 公開日 2019-08-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Thymidylate synthase fragment screening To be published
1ZOP	CD11A I-DOMAIN WITH BOUND MAGNESIUM ION 分子名称: CHLORIDE ION, I-DOMAIN FRAGMENT OF LFA-1, MANGANESE (II) ION 著者 Leahy, D.J, Qu, A. 登録日 1996-06-21 公開日 1996-12-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin. Structure, 4, 1996
8TLG	CDCA7 (Mouse) Binds Non-B-form 34-mer DNA oligo 分子名称: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (34-MER), ... 著者 Horton, J.R, Ren, R, Cheng, X. 登録日 2023-07-26 公開日 2024-08-21 最終更新日 2024-08-28 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA. Biorxiv, 2023
4LBT	Endothiapepsin in complex with 100mM acylhydrazone inhibitor 分子名称: (2S)-2-azanyl-3-(3H-indol-3-yl)-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]propanamide, DIMETHYL SULFOXIDE, Endothiapepsin, ... 著者 Radeva, N, Heine, A, Winquist, J, Klebe, G. 登録日 2013-06-21 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.251 Å) 主引用文献 Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry. Angew.Chem.Int.Ed.Engl., 53, 2014

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