PDB: 47902 件ウェブページステータス検索Chemie searchBIRD

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6DC5	RSV prefusion F in complex with AM22 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Jones, H.G, McLellan, J.S. 登録日 2018-05-04 公開日 2019-07-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
4MUI	Crystal structure of pantothenate synthetase in complex with 2-(5-methoxy-2-(4-methoxyphenylsulfonylcarbamoyl)-1H-indol-1-yl)acetic acid 分子名称: (5-methoxy-2-{[(4-methoxyphenyl)sulfonyl]carbamoyl}-1H-indol-1-yl)acetic acid, 1,2-ETHANEDIOL, ETHANOL, ... 著者 Silvestre, H.L, Blundell, T.L. 登録日 2013-09-22 公開日 2014-08-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Optimization of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase Based on Group Efficiency Analysis. Chemmedchem, 11, 2016
6DIC	D276G DNA polymerase beta substrate complex with templating cytosine and incoming Fapy-dGTP analog 分子名称: 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, CHLORIDE ION, ... 著者 Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. 登録日 2018-05-23 公開日 2019-01-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
7NS0	Bacilladnavirus capsid structure 分子名称: Capsid protein VP2 著者 Munke, A, Okamoto, K. 登録日 2021-03-05 公開日 2022-07-20 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Primordial Capsid and Spooled ssDNA Genome Structures Unravel Ancestral Events of Eukaryotic Viruses. Mbio, 13, 2022
4N9O	Probing the N-terminal beta-sheet conversion in the crystal structure of the human prion protein bound to a Nanobody 分子名称: Major prion protein, Nanobody Nb484 著者 Abskharon, R.N.N, Giachin, G, Wohlkonig, A, Soror, S.H, Pardon, E, Legname, G, Steyaert, J. 登録日 2013-10-21 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Probing the N-Terminal beta-Sheet Conversion in the Crystal Structure of the Human Prion Protein Bound to a Nanobody. J.Am.Chem.Soc., 136, 2014
4MV6	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with Phosphonoacetamide 分子名称: 1,2-ETHANEDIOL, Biotin carboxylase, PHOSPHONOACETAMIDE 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. 登録日 2013-09-23 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
7NWE	CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC BRANCHED-CHAIN AMINOTRANSFERASE (BCAT1) IN COMPLEX WITH PLP AND INHIBITOR COMPOUND 10 分子名称: 4-[2,4-bis(oxidanylidene)-6-(trifluoromethyl)-1H-pyrimidin-3-yl]-5-methyl-2-(2-methylphenoxy)benzenecarbonitrile, Branched-chain-amino-acid aminotransferase, cytosolic, ... 著者 Hillig, R.C. 登録日 2021-03-16 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 BAY-069, a Novel (Trifluoromethyl)pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe. J.Med.Chem., 65, 2022
7QHO	Cytochrome bcc-aa3 supercomplex (respiratory supercomplex III2/IV2) from Corynebacterium glutamicum (as isolated) 分子名称: (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... 著者 Kao, W.-C, Hunte, C. 登録日 2021-12-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for safe and efficient energy conversion in a respiratory supercomplex Nature Communications, 13, 2022
8U6C	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 2-chloro-N-(4-chloro-3-(3-chloro-5-cyanophenoxy)phenethyl)acetamide (JLJ732), a non-nucleoside inhibitor 分子名称: 2-chloro-N-{2-[4-chloro-3-(3-chloro-5-cyanophenoxy)phenyl]ethyl}acetamide, Reverse transcriptase/ribonuclease H, p51 RT 著者 Hollander, K, Henry, S, Jorgensen, W.L, Anderson, K.S. 登録日 2023-09-13 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Covalent and noncovalent strategies for targeting Lys102 in HIV-1 reverse transcriptase. Eur.J.Med.Chem., 262, 2023
6DJB	Structure of human Volume Regulated Anion Channel composed of SWELL1 (LRRC8A) 分子名称: Volume-regulated anion channel subunit LRRC8A 著者 Kefauver, J.M, Saotome, K, Pallesen, J, Cottrell, C.A, Ward, A.B, Patapoutian, A. 登録日 2018-05-24 公開日 2018-08-15 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structure of the human volume regulated anion channel. Elife, 7, 2018
4MWQ	Anhui N9-oseltamivir carboxylate 分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Wu, Y, Qi, J.X, Gao, F, Gao, G.F. 登録日 2013-09-25 公開日 2013-11-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses Cell Res., 23, 2013
7QHM	Cytochrome bcc-aa3 supercomplex (respiratory supercomplex III2/IV2) from Corynebacterium glutamicum (stigmatellin and azide bound) 分子名称: (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, AZIDE ION, ... 著者 Kao, W.-C, Hunte, C. 登録日 2021-12-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for safe and efficient energy conversion in a respiratory supercomplex. Nat Commun, 13, 2022
7O9T	Crystal structure of Human Menin in apo form 分子名称: 1,2-ETHANEDIOL, Menin 著者 Groves, M.R, Gao, K. 登録日 2021-04-17 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.159 Å) 主引用文献 Crystal structure of Human Menin in apo form To Be Published
6GM9	Human Carbonic Anhydrase II in complex with 4-Methylbenzenesulfonamide 分子名称: 4-methylbenzenesulfonamide, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2018-05-24 公開日 2019-06-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.089 Å) 主引用文献 Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors. Acs Chem.Biol., 15, 2020
4NAH	Inhibitors of 4-Phosphopanthetheine Adenylyltransferase (PPAT) 分子名称: 2-[(2-{(1S,2S)-2-[(3,4-dichlorobenzyl)carbamoyl]cyclohexyl}-6-ethylpyrimidin-4-yl)sulfanyl]-1H-imidazole-5-carboxylic acid, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Phosphopantetheine adenylyltransferase 著者 Lahiri, S.D. 登録日 2013-10-22 公開日 2014-03-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Discovery of inhibitors of 4'-phosphopantetheine adenylyltransferase (PPAT) to validate PPAT as a target for antibacterial therapy. Antimicrob.Agents Chemother., 57, 2013
6GMZ	Staphylopine dehydrogenase in complex with Histidine tag and citrate 分子名称: ALA-HIS-HIS-ALA, AMMONIUM ION, CITRIC ACID, ... 著者 Hajjar, C, Arnoux, P. 登録日 2018-05-29 公開日 2019-04-10 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Control by Metals of Staphylopine Dehydrogenase Activity during Metallophore Biosynthesis. J.Am.Chem.Soc., 141, 2019
4MXJ	Thermolysin in complex with UBTLN35 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Krimmer, S.G, Heine, A, Klebe, G. 登録日 2013-09-26 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.349 Å) 主引用文献 Methyl, Ethyl, Propyl, Butyl: Futile But Not for Water, as the Correlation of Structure and Thermodynamic Signature Shows in a Congeneric Series of Thermolysin Inhibitors. Chemmedchem, 4, 2014
6DM6	Structure of DNA polymerase III subunit beta from Rickettsia conorii in complex with a natural product 分子名称: Beta sliding clamp, Natural product peptide 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-06-04 公開日 2019-06-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of DNA polymerase III subunit beta from Rickettsia conorii in complex with a natural product to be published
4MY7	frog M ferritin iron-loaded under anaerobic environment 分子名称: CHLORIDE ION, FE (II) ION, Ferritin, ... 著者 Mangani, S, Di Pisa, F, Pozzi, C, Turano, P, Lalli, D. 登録日 2013-09-27 公開日 2014-09-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Time-lapse anomalous X-ray diffraction shows how Fe(2+) substrate ions move through ferritin protein nanocages to oxidoreductase sites. Acta Crystallogr.,Sect.D, 71, 2015
6DMN	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Soaked in 2 mM Ca2+ and 200 mM K+ at 21 C 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-05 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
4NAZ	Crystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.15 Angstrom Resolution 分子名称: GLYCEROL, Metallothiol transferase FosB, SULFATE ION, ... 著者 Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Cook, P.D, Armstrong, R.N. 登録日 2013-10-22 公開日 2014-02-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry, 53, 2014
8TRG	Structure of full-length LexA bound to a RecA filament 分子名称: DNA (27-MER), LexA repressor, MAGNESIUM ION, ... 著者 Cory, M.B, Li, A, Kohli, R.M. 登録日 2023-08-09 公開日 2023-11-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 The LexA-RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation. Nat.Struct.Mol.Biol., 2024
6GV9	Structure of the type IV pilus from enterohemorrhagic Escherichia coli (EHEC) 分子名称: Prepilin peptidase-dependent protein D 著者 Bardiaux, B, Amorim, G.C, Luna-Rico, A, Zheng, W, Guilvout, I, Jollivet, C, Nilges, M, Egelman, E, Francetic, O, Izadi-Pruneyre, N. 登録日 2018-06-20 公開日 2019-05-15 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus. Structure, 27, 2019
3W3M	Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 2 分子名称: 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... 著者 Tanji, H, Ohto, U, Shimizu, T. 登録日 2012-12-22 公開日 2013-04-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands Science, 339, 2013
6DMW	Calmodulin-bound full-length rbTRPV5 分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5 著者 Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2018-06-05 公開日 2018-10-24 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural insights on TRPV5 gating by endogenous modulators. Nat Commun, 9, 2018

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