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5HIU
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BU of 5hiu by Molmil
Structure of the TSC2 N-terminus
分子名称: GTPase activator-like protein
著者Zech, R, Kiontke, S, Kummel, D.
登録日2016-01-12
公開日2016-08-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis.
J.Biol.Chem., 291, 2016
3C4W
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BU of 3c4w by Molmil
Crystal Structure of G protein coupled receptor kinase 1 bound to ATP and magnesium chloride at 2.7A
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Singh, P, Tesmer, J.J.G.
登録日2008-01-30
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation.
J.Biol.Chem., 283, 2008
2Q0Z
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BU of 2q0z by Molmil
Crystal structure of Q9P172/Sec63 from Homo sapiens. Northeast Structural Genomics Target HR1979.
分子名称: Protein PRO2281
著者Benach, J, Neely, H, Abashidze, M, Edstrom, W.C, Seetharaman, J, Zhao, L, Fang, Y, Cunningham, K, Owens, L, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2007-05-23
公開日2007-06-05
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Q9P172/Sec63 from Homo sapiens.
To be Published
3KA8
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BU of 3ka8 by Molmil
Frog M-ferritin, EQH mutant, with cobalt
分子名称: CHLORIDE ION, COBALT (II) ION, Ferritin, ...
著者Tosha, T, Ng, H.L, Theil, E, Alber, T, Bhattasali, O.
登録日2009-10-19
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Moving Metal Ions through Ferritin-Protein Nanocages from Three-Fold Pores to Catalytic Sites.
J.Am.Chem.Soc., 132, 2010
1OAQ
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BU of 1oaq by Molmil
Free conformation Ab1 of the IgE SPE-7
分子名称: HEAVY CHAIN, LIGHT CHAIN
著者James, L.C, Roversi, P, Tawfik, D.
登録日2003-01-21
公開日2004-01-15
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
3JC9
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BU of 3jc9 by Molmil
Architectural model of the type IVa pilus machine in a non-piliated state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PilA, ...
著者Chang, Y.-W, Rettberg, L.A, Jensen, G.J.
登録日2015-11-24
公開日2016-03-16
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY
主引用文献Architecture of the type IVa pilus machine.
Science, 351, 2016
3JS2
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BU of 3js2 by Molmil
Crystal structure of minimal kinase domain of fibroblast growth factor receptor 1 in complex with 5-(2-thienyl)nicotinic acid
分子名称: 5-(2-thienyl)nicotinic acid, Basic fibroblast growth factor receptor 1, PHOSPHATE ION
著者Bae, J.H, Ravindranathan, K.P, Mandiyan, V, Ekkati, A.R, Schlessinger, J, Jorgensen, W.L.
登録日2009-09-09
公開日2010-02-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening
J.Med.Chem., 53, 2010
5TED
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BU of 5ted by Molmil
Effector binding domain of QuiR in complex with shikimate
分子名称: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, His Tag peptide, Lmo0488 protein
著者Prezioso, S.M, Christendat, D.
登録日2016-09-21
公開日2017-10-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.889 Å)
主引用文献Shikimate Induced Transcriptional Activation of Protocatechuate Biosynthesis Genes by QuiR, a LysR-Type Transcriptional Regulator, in Listeria monocytogenes.
J. Mol. Biol., 430, 2018
5HGM
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BU of 5hgm by Molmil
Hexameric HIV-1 CA in complex with dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Capsid protein P24
著者Jacques, D.A, James, L.C.
登録日2016-01-08
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536, 2016
3J34
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BU of 3j34 by Molmil
Structure of HIV-1 Capsid Protein by Cryo-EM
分子名称: capsid protein
著者Zhao, G, Perilla, J.R, Yufenyuy, E, Meng, X, Chen, B, Ning, J, Ahn, J, Gronenborn, A.M, Schulten, K, Aiken, C, Zhang, P.
登録日2013-02-23
公開日2013-05-29
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
3BO8
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BU of 3bo8 by Molmil
The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Kumar, P, Vahedi-Faridi, A, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2007-12-17
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity
Protein Sci., 18, 2009
3JSW
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BU of 3jsw by Molmil
Human PDE9 in complex with selective inhibitor
分子名称: 6-[(3S,4S)-1-benzyl-4-methylpyrrolidin-3-yl]-1-(1-methylethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ...
著者Liu, S.
登録日2009-09-11
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy.
J.Med.Chem., 52, 2009
5HIO
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BU of 5hio by Molmil
Crystal Structure of PQS Response Protein PqsE in Complex with 2-aminobenzoylacetate
分子名称: 3-(2-aminophenyl)-3-oxopropanoic acid, FE (III) ION, PqsE
著者Witzgall, F, Blankenfeldt, W.
登録日2016-01-12
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.
Acs Chem.Biol., 11, 2016
3JT6
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BU of 3jt6 by Molmil
Structure of neuronal nitric oxide synthase heme domain complexed with N~5~-[4-(methylsulfanyl)butanimidoyl]-L-ornithine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, Nitric oxide synthase, ...
著者Li, H, Poulos, T.L.
登録日2009-09-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Heme-coordinating inhibitors of neuronal nitric oxide synthase. Iron-thioether coordination is stabilized by hydrophobic contacts without increased inhibitor potency.
J.Am.Chem.Soc., 132, 2010
3JTL
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BU of 3jtl by Molmil
Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator
分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
著者Stadtmueller, B.M, Whitby, F.G, Hill, C.P.
登録日2009-09-12
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Models for Interactions between the 20S proteasome and its PAN/19S activators.
J.Biol.Chem., 285, 2010
3JVL
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BU of 3jvl by Molmil
Crystal structure of bromodomain 2 of mouse Brd4
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Bromodomain-containing protein 4
著者Vollmuth, F, Blankenfeldt, W, Geyer, M.
登録日2009-09-17
公開日2009-10-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
3BSO
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BU of 3bso by Molmil
Norwalk Virus polymerase bound to cytidine 5'-triphosphate and primer-template RNA
分子名称: CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ...
著者Zamyatkin, D.F, Ng, K.K.S.
登録日2007-12-26
公開日2008-01-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase.
J.Biol.Chem., 283, 2008
1RQ2
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BU of 1rq2 by Molmil
MYCOBACTERIUM TUBERCULOSIS FTSZ IN COMPLEX WITH CITRATE
分子名称: CITRIC ACID, Cell division protein ftsZ
著者Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W.
登録日2003-12-04
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.
J.Mol.Biol., 342, 2004
2NYE
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BU of 2nye by Molmil
Crystal structure of the Bateman2 domain of yeast Snf4
分子名称: Nuclear protein SNF4
著者Rudolph, M.J, Amodeo, G.A, Iram, S, Hong, S, Pirino, G, Carlson, M, Tong, L.
登録日2006-11-20
公開日2006-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.
Structure, 15, 2007
5SV1
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BU of 5sv1 by Molmil
Structure of the ExbB/ExbD complex from E. coli at pH 4.5
分子名称: Biopolymer transport protein ExbB, Biopolymer transport protein ExbD, MERCURY (II) ION
著者Celia, H, Botos, I, Lloubes, R, Buchanan, S.K, Noinaj, N.
登録日2016-08-04
公開日2016-09-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural insight into the role of the Ton complex in energy transduction.
Nature, 538, 2016
2NYM
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BU of 2nym by Molmil
Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit
分子名称: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
著者Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y.
登録日2006-11-21
公開日2006-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006
3JT3
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BU of 3jt3 by Molmil
Structure of neuronal nitric oxide synthase heme domain complexed with N~5~-[2-(methylsulfanyl)ethanimidoyl]-L-ornithine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, Nitric oxide synthase, ...
著者Li, H, Poulos, T.L.
登録日2009-09-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Heme-coordinating inhibitors of neuronal nitric oxide synthase. Iron-thioether coordination is stabilized by hydrophobic contacts without increased inhibitor potency.
J.Am.Chem.Soc., 132, 2010
1RMO
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BU of 1rmo by Molmil
Probing the Role of Tryptophans in Aequorea Victoria Green Fluorescent Proteins with an Expanded Genetic Code
分子名称: wunen-nonfunctional GFP fusion protein
著者Budisa, N, Pal, P.P, Alefelder, S, Birle, P, Krywcun, T, Rubini, M, Wenger, W, Bae, J.H, Steiner, T.
登録日2003-11-28
公開日2004-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code
Biol.Chem., 385, 2004
5SXM
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BU of 5sxm by Molmil
WDR5 in complex with MLL Win motif peptidomimetic
分子名称: ACE-ALA-ARG-THR-GLU-VAL-TYR-NH2, WD repeat-containing protein 5
著者Alicea-Velazquez, N.L, Shinsky, S.A, Cosgrove, M.S.
登録日2016-08-09
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.
J.Biol.Chem., 291, 2016
5EF3
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BU of 5ef3 by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 25.0 MGy
分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
著者Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
登録日2015-10-23
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016

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