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2X9N
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BU of 2x9n by Molmil
High resolution structure of TbPTR1 in complex with cyromazine
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, ACETATE ION, DITHIANE DIOL, ...
著者Dawson, A, Tulloch, L.B, Barrack, K.L, Hunter, W.N.
登録日2010-03-23
公開日2010-06-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献High-Resolution Structures of Trypanosoma Brucei Pteridine Reductase Ligand Complexes Inform on the Placement of New Molecular Entities in the Active Site of a Potential Drug Target
Acta Crystallogr.,Sect.D, 66, 2010
2X9V
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High resolution structure of TbPTR1 with trimetrexate
分子名称: ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE, ...
著者Dawson, A, Tulloch, L.B, Barrack, K.L, Hunter, W.N.
登録日2010-03-24
公開日2010-06-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献High-Resolution Structures of Trypanosoma Brucei Pteridine Reductase Ligand Complexes Inform on the Placement of New Molecular Entities in the Active Site of a Potential Drug Target
Acta Crystallogr.,Sect.D, 66, 2010
8RDW
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BU of 8rdw by Molmil
Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon and EF-Tu(GDP) (structure 3).
分子名称: 16S rRNA, 23S rRNA, 5S rRNA, ...
著者Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V.
登録日2023-12-08
公開日2024-02-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
8RD8
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BU of 8rd8 by Molmil
Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factors Balon and RaiA (structure 1).
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S30, ...
著者Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V.
登録日2023-12-07
公開日2024-02-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
8RDV
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BU of 8rdv by Molmil
Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon, mRNA and P-site tRNA (structure 2).
分子名称: 16S rRNA, 23S rRNA, 5S rRNA, ...
著者Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V.
登録日2023-12-08
公開日2024-02-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
7UYN
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BU of 7uyn by Molmil
Crystal structure of B-form alien DNA 5'-CTTBPPBBSSZZSAAG in a host-guest complex with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase
分子名称: DNA (5'-D(*CP*TP*TP*(IGU)P*(1WA)P*(1WA)P*(IGU)P*(IGU))-3'), DNA (5'-D(P*(JSP)P*(JSP)P*(1W5)P*(1W5)P*(JSP)P*AP*AP*G)-3'), reverse transcriptase
著者Georgiadis, M.M.
登録日2022-05-06
公開日2023-05-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of 'ALternative Isoinformational ENgineered' DNA in B-form.
Philos.Trans.R.Soc.Lond.B Biol.Sci., 378, 2023
6CMN
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BU of 6cmn by Molmil
Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7
分子名称: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element
著者Belashov, I.A, Wedekind, J.E.
登録日2018-03-05
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription.
Nucleic Acids Res., 46, 2018
4M38
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BU of 4m38 by Molmil
Crystal structure of Trypanosoma brucei protein arginine methyltransferase 7 complex with AdoHcy and histone H4 peptide
分子名称: Histone H4, Protein arginine N-methyltransferase 7, S-ADENOSYL-L-HOMOCYSTEINE
著者Wang, C, Zhu, Y, Shi, Y.
登録日2013-08-06
公開日2014-04-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
Structure, 22, 2014
4M36
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BU of 4m36 by Molmil
Crystal structure of Trypanosoma brucei protein arginine methyltransferase 7
分子名称: Protein arginine N-methyltransferase 7
著者Wang, C, Zhu, Y, Shi, Y.
登録日2013-08-06
公開日2014-04-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.042 Å)
主引用文献Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
Structure, 22, 2014
1SJR
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BU of 1sjr by Molmil
NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
分子名称: Polypyrimidine tract-binding protein 1
著者Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J.
登録日2004-03-04
公開日2004-09-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and RNA Interactions of the N-Terminal RRM Domains of PTB
Structure, 12, 2004
6RX6
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BU of 6rx6 by Molmil
Trypanosoma brucei PTR1 (TbPTR1) in complex with inhibitor 4 (NMT-C0026)
分子名称: ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pteridine reductase, ...
著者Landi, G, Pozzi, C, Mangani, S.
登録日2019-06-07
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
J.Med.Chem., 65, 2022
4M37
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BU of 4m37 by Molmil
Crystal structure of Trypanosoma brucei protein arginine methyltransferase 7 complex with AdoHcy
分子名称: Protein arginine N-methyltransferase 7, S-ADENOSYL-L-HOMOCYSTEINE
著者Wang, C, Zhu, Y, Shi, Y.
登録日2013-08-06
公開日2014-04-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.
Structure, 22, 2014
2QRY
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BU of 2qry by Molmil
Periplasmic thiamin binding protein
分子名称: THIAMIN PHOSPHATE, Thiamine-binding periplasmic protein
著者Ealick, S.E, Soriano, E.V.
登録日2007-07-30
公開日2008-02-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Similarities between Thiamin-Binding Protein and Thiaminase-I Suggest a Common Ancestor
Biochemistry, 47, 2008
1SJQ
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BU of 1sjq by Molmil
NMR Structure of RRM1 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
分子名称: Polypyrimidine tract-binding protein 1
著者Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J.
登録日2004-03-04
公開日2004-09-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and RNA Interactions of the N-Terminal RRM Domains of PTB
Structure, 12, 2004
8BGF
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BU of 8bgf by Molmil
NMR solution structure of the N-terminal RRM and flanking linker regions of Polypyrimidine tract binding protein 1 using the CYANA CONSENSUS method.
分子名称: Polypyrimidine tract-binding protein 1
著者Damberger, F.D, Beusch, I, Allain, F.H.-T.
登録日2022-10-27
公開日2023-11-08
最終更新日2024-09-04
実験手法SOLUTION NMR
主引用文献N-terminal domain of polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition.
Nucleic Acids Res., 2024
2L15
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BU of 2l15 by Molmil
Solution Structure of Cold Shock Protein CspA Using Combined NMR and CS-Rosetta method
分子名称: Cold shock protein CspA
著者Tang, Y, Schneider, W.M, Shen, Y, Raman, S, Inouye, M, Baker, D, Roth, M.J, Montelione, G.T.
登録日2010-07-22
公開日2010-09-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Fully automated high-quality NMR structure determination of small (2)H-enriched proteins.
J Struct Funct Genomics, 11, 2010
2YMD
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BU of 2ymd by Molmil
Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with serotonin (5-hydroxytryptamine)
分子名称: GLYCEROL, PHOSPHATE ION, SEROTONIN, ...
著者Kesters, D, Thompson, A.J, Brams, M, Elk, R.v, Spurny, R, Geitmann, M, Villalgordo, J.M, Guskov, A, Danielson, U.H, Lummis, S.C.R, Smit, A.B, Ulens, C.
登録日2012-10-09
公開日2012-12-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural Basis of Ligand Recognition in 5-Ht(3) Receptors.
Embo Rep., 14, 2013
2C7V
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BU of 2c7v by Molmil
Structure of Trypanosoma brucei pteridine reductase (PTR1) in ternary complex with cofactor and the antifolate methotrexate
分子名称: ACETATE ION, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Dawson, A, Gibellini, F, Sienkiewicz, N, Fyfe, P.K, McLuskey, K, Fairlamb, A.H, Hunter, W.N.
登録日2005-11-29
公開日2006-09-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and Reactivity of Trypanosoma Brucei Pteridine Reductase: Inhibition by the Archetypal Antifolate Methotrexate
Mol.Microbiol., 61, 2006
2N3O
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BU of 2n3o by Molmil
Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA
分子名称: Polypyrimidine tract-binding protein 1, RNA (5'-R(*GP*GP*GP*AP*CP*CP*UP*GP*GP*UP*CP*UP*UP*UP*CP*CP*AP*GP*GP*UP*CP*CP*C)-3')
著者Maris, C, Jayne, S.F, Damberger, F.F, Ravindranathan, S, Allain, F.H.-T.
登録日2015-06-08
公開日2016-08-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献C-terminal helix folding upon pyrimidine-rich hairpin binding to PTB RRM1. Implications for PTB function in Encephalomyocarditis virus IRES activity.
To be Published
1BRQ
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BU of 1brq by Molmil
CRYSTAL STRUCTURE OF THE TRIGONAL FORM OF HUMAN PLASMA RETINOL-BINDING PROTEIN AT 2.5 ANGSTROMS RESOLUTION
分子名称: RETINOL BINDING PROTEIN
著者Zanotti, G, Monaco, H.L.
登録日1992-07-27
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the trigonal form of human plasma retinol-binding protein at 2.5 A resolution.
J.Mol.Biol., 230, 1993
1BRP
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BU of 1brp by Molmil
CRYSTAL STRUCTURE OF THE TRIGONAL FORM OF HUMAN PLASMA RETINOL-BINDING PROTEIN AT 2.5 ANGSTROMS RESOLUTION
分子名称: RETINOL, RETINOL BINDING PROTEIN
著者Zanotti, G, Monaco, H.L.
登録日1992-07-27
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the trigonal form of human plasma retinol-binding protein at 2.5 A resolution.
J.Mol.Biol., 230, 1993
1AQB
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BU of 1aqb by Molmil
RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA
分子名称: CADMIUM ION, RETINOL, RETINOL-BINDING PROTEIN
著者Zanotti, G, Panzalorto, M, Marcato, A, Malpeli, G, Folli, C, Berni, R.
登録日1997-07-28
公開日1998-01-28
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of pig plasma retinol-binding protein at 1.65 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
1JYJ
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BU of 1jyj by Molmil
Crystal Structure of a Double Variant (W67L/W91H) of Recombinant Human Serum Retinol-binding Protein at 2.0 A Resolution
分子名称: GLYCEROL, PLASMA RETINOL-BINDING PROTEIN
著者Greene, L.H, Chrysina, E.D, Irons, L.I, Papageorgiou, A.C, Acharya, K.R, Brew, K.
登録日2001-09-12
公開日2003-07-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Conserved Residues in Structure and Stability: Tryptophans of Human Serum Retinol-Binding Protein, a Model for the Lipocalin Superfamily
Protein Sci., 10, 2001
1KT3
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BU of 1kt3 by Molmil
Crystal structure of bovine holo-RBP at pH 2.0
分子名称: Plasma retinol-binding protein, RETINOL
著者Calderone, V, Berni, R, Zanotti, G.
登録日2002-01-15
公開日2003-06-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution Structures of Retinol-binding Protein in Complex with Retinol: pH-induced Protein Structural Changes in the Crystal State
J.Mol.Biol., 329, 2003
1KT7
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BU of 1kt7 by Molmil
Crystal structure of bovine holo-RBP at pH 7.0
分子名称: Plasma retinol-binding protein, RETINOL
著者Calderone, V, Berni, R, Zanotti, G.
登録日2002-01-15
公開日2003-06-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.274 Å)
主引用文献High-resolution Structures of Retinol-binding Protein in Complex with Retinol: pH-induced Protein Structural Changes in the Crystal State
J.Mol.Biol., 329, 2003

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