7VR5
| Crystal structure of CmABCB1 W114Y/W161Y/W363Y/W364Y/M391W (4WY/M391W) mutant | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DECYL-BETA-D-MALTOPYRANOSIDE, Probable ATP-dependent transporter ycf16 | 著者 | Inoue, Y, Ogawa, H, Kato, H. | 登録日 | 2021-10-21 | 公開日 | 2022-09-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure-based alteration of tryptophan residues of the multidrug transporter CmABCB1 to assess substrate binding using fluorescence spectroscopy. Protein Sci., 31, 2022
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7V5C
| Cryo-EM structure of the mouse ABCB9 (ADP.BeF3-bound) | 分子名称: | ABC-type oligopeptide transporter ABCB9, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Kim, J.W, Ju, S, Min, D.S, Jin, M.S. | 登録日 | 2021-08-17 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase. Nat Commun, 13, 2022
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7VFI
| Cryo-EM structure of the mouse TAPL (9mer-peptide bound) | 分子名称: | ABC-type oligopeptide transporter ABCB9, ARG-ARG-TYR-GLN-LYS-SER-THR-GLU-LEU, CHOLESTEROL HEMISUCCINATE | 著者 | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Kim, J.W, Ju, S, Min, D.S, Jin, M.S. | 登録日 | 2021-09-13 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase. Nat Commun, 13, 2022
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7V5D
| Cryo-EM structure of the mouse ABCB9 (PG-bound) | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ABC-type oligopeptide transporter ABCB9 | 著者 | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Ju, S, Kim, J.W, Min, D.S, Jin, M.S. | 登録日 | 2021-08-17 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase. Nat Commun, 13, 2022
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6P6I
| Structure of YbtPQ importer | 分子名称: | ABC transporter protein, inner membrane ABC-transporter | 著者 | Wang, Z, Hu, W, Zheng, H. | 登録日 | 2019-06-04 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter. Sci Adv, 6, 2020
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6PAO
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6PAR
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6PZB
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6PZI
| Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8 | 著者 | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | 登録日 | 2019-07-31 | 公開日 | 2019-08-14 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
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6PZA
| Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide | 分子名称: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | 登録日 | 2019-07-31 | 公開日 | 2019-08-14 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
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6Q81
| Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, P-glycoprotein (ABCB1) | 著者 | Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. | 登録日 | 2018-12-13 | 公開日 | 2018-12-26 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution. Bmc Struct.Biol., 18, 2018
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6PZ9
| Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ... | 著者 | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | 登録日 | 2019-07-31 | 公開日 | 2019-08-14 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
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6QV2
| Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM#2 | 分子名称: | ABC transporter, ATP-binding protein, MAGNESIUM ION, ... | 著者 | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | 登録日 | 2019-03-01 | 公開日 | 2019-05-29 | 最終更新日 | 2019-06-05 | 実験手法 | X-RAY DIFFRACTION (4.23 Å) | 主引用文献 | The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
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6QV1
| Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM1 | 分子名称: | ABC transporter, ATP-binding protein, MAGNESIUM ION, ... | 著者 | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | 登録日 | 2019-03-01 | 公開日 | 2019-05-29 | 最終更新日 | 2019-06-05 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
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6QV0
| Structure of ATP-bound outward-facing TM287/288 in complex with sybody Sb_TM35 | 分子名称: | ABC transporter, ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | 登録日 | 2019-03-01 | 公開日 | 2019-05-29 | 最終更新日 | 2019-06-05 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
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6R72
| Crystal structure of BmrA-E504A in an outward-facing conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug exporter ATP-binding cassette | 著者 | Chaptal, V, Zampieri, V, Kilburg, A, Magnard, S, Falson, P. | 登録日 | 2019-03-28 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
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6R81
| Multidrug resistance transporter BmrA mutant E504A bound with ATP and Mg solved by Cryo-EM | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION | 著者 | Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P. | 登録日 | 2019-03-30 | 公開日 | 2020-05-06 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
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6RAN
| Heterodimeric ABC exporter TmrAB in inward-facing wide conformation | 分子名称: | Multidrug resistance ABC transporter ATP-binding and permease protein, Nanobody Nb9F10 | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAG
| Heterodimeric ABC exporter TmrAB in inward-facing wide conformation under turnover conditions | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6QUZ
| Structure of ATPgS-bound outward-facing TM287/288 in complex with sybody Sb_TM35 | 分子名称: | ABC transporter, ATP-binding protein, MAGNESIUM ION, ... | 著者 | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | 登録日 | 2019-03-01 | 公開日 | 2019-05-29 | 最終更新日 | 2019-06-05 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
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6QEX
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6RAH
| Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing open conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAM
| Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation with wider opened intracellular gate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAJ
| Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing open conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAK
| Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing occluded conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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