2VNE
| The X-ray structure of Norcoclaurine synthase from Thalictrum flavum | 分子名称: | S-NORCOCLAURINE SYNTHASE | 著者 | Ilari, A, Franceschini, S, Boffi, A, Bonamore, A, Pasquo, A. | 登録日 | 2008-02-04 | 公開日 | 2008-08-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Structural Basis of Enzymatic S-Norcoclaurine Biosynthesis. J.Biol.Chem., 284, 2009
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5ZMP
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5CAL
| EGFR kinase domain mutant "TMLR" with compound 24 | 分子名称: | 2,2-dimethyl-3-[(4-{[2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-yl]amino}pyrimidin-2-yl)amino]propanamide, Epidermal growth factor receptor | 著者 | Eigenbrot, C, Yu, C. | 登録日 | 2015-06-29 | 公開日 | 2015-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. J.Med.Chem., 58, 2015
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4Z88
| SH3-II of Drosophila Rim-binding protein with Aplip1 peptide | 分子名称: | JNK-interacting protein 1, PHOSPHATE ION, RIM-binding protein, ... | 著者 | Driller, J.H, Holton, N, Siebert, M, Boehme, M.A, Wahl, M.C, Sigrist, S.J, Loll, B. | 登録日 | 2015-04-08 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones. Elife, 4, 2015
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5CAX
| CRYSTAL STRUCTURE OF METHANOSARCINA ACETIVORANS METHANOREDOXIN | 分子名称: | ACETIC ACID, CADMIUM ION, Glutaredoxin, ... | 著者 | Yennawar, N.H, Yennawar, H.P, Ferry, G.J. | 登録日 | 2015-06-30 | 公開日 | 2016-02-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | 主引用文献 | Structural and Biochemical Characterizations of Methanoredoxin from Methanosarcina acetivorans, a Glutaredoxin-Like Enzyme with Coenzyme M-Dependent Protein Disulfide Reductase Activity. Biochemistry, 55, 2016
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2G6L
| Structure of rat nNOS heme domain (BH2 bound) complexed with NO | 分子名称: | 7,8-DIHYDROBIOPTERIN, ACETATE ION, ARGININE, ... | 著者 | Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L. | 登録日 | 2006-02-24 | 公開日 | 2006-08-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural studies of constitutive nitric oxide synthases with diatomic ligands bound. J.Biol.Inorg.Chem., 11, 2006
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1K2H
| Three-dimensional Solution Structure of apo-S100A1. | 分子名称: | S-100 protein, alpha chain | 著者 | Rustandi, R.R, Baldisseri, D.M, Inman, K.G, Nizner, P, Hamilton, S.M, Landar, A, Landar, A, Zimmer, D.B, Weber, D.J. | 登録日 | 2001-09-27 | 公開日 | 2002-02-13 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of the calcium-signaling protein apo-S100A1 as determined by NMR. Biochemistry, 41, 2002
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4ZKT
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4Z98
| Crystal Structure of Hen Egg White Lysozyme using Serial X-ray Diffraction Data Collection | 分子名称: | ACETATE ION, Lysozyme C | 著者 | Murray, T.D, Lyubimov, A.Y, Ogata, C.M, Uervirojnangkoorn, M, Brunger, A.T, Berger, J.M. | 登録日 | 2015-04-10 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | A high-transparency, micro-patternable chip for X-ray diffraction analysis of microcrystals under native growth conditions. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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1JFJ
| NMR SOLUTION STRUCTURE OF AN EF-HAND CALCIUM BINDING PROTEIN FROM ENTAMOEBA HISTOLYTICA | 分子名称: | CALCIUM-BINDING PROTEIN | 著者 | Atreya, H.S, Sahu, S.C, Bhattacharya, A, Chary, K.V.R, Govil, G. | 登録日 | 2001-06-20 | 公開日 | 2001-12-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR derived solution structure of an EF-hand calcium-binding protein from Entamoeba Histolytica. Biochemistry, 40, 2001
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2V9Y
| Human aminoimidazole ribonucleotide synthetase | 分子名称: | PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE, SULFATE ION | 著者 | Welin, M, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Herman, M.D, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2007-08-28 | 公開日 | 2007-09-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Studies of Tri-Functional Human Gart. Nucleic Acids Res., 38, 2010
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2FNB
| NMR STRUCTURE OF THE FIBRONECTIN ED-B DOMAIN, NMR, 20 STRUCTURES | 分子名称: | PROTEIN (FIBRONECTIN) | 著者 | Fattorusso, R, Pellecchia, M, Viti, F, Neri, P, Neri, D, Wuthrich, K. | 登録日 | 1998-12-16 | 公開日 | 1998-12-23 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the human oncofoetal fibronectin ED-B domain, a specific marker for angiogenesis. Structure Fold.Des., 7, 1999
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4HXR
| Brd4 Bromodomain 1 complex with N-[3-(2-OXO-2,3-DIHYDRO-1,3-THIAZOL-4-YL)PHENYL]THIOPHENE-2-SULFONAMIDE inhibitor | 分子名称: | Bromodomain-containing protein 4, N-[3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)phenyl]thiophene-2-sulfonamide | 著者 | Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. | 登録日 | 2012-11-12 | 公開日 | 2013-04-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
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2VFP
| Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V349L | 分子名称: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN, ... | 著者 | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | 登録日 | 2007-11-05 | 公開日 | 2008-12-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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5C0C
| 1E6 TCR in complex with HLA-A02 carrying RQFGPDWIVA | 分子名称: | 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.974 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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5ZQD
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5C07
| 1E6 TCR in complex with HLA-A02 carrying YQFGPDFPIA | 分子名称: | 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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4ZQC
| Tryptophan Synthase from Salmonella typhimurium in complex with two molecules of N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor in the alpha-site and a single F6F molecule in the beta-site at 1.54 Angstrom resolution. | 分子名称: | 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DIMETHYL SULFOXIDE, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Hilario, E, Caulkins, B.G, Young, R.P, Dunn, M.F, Mueller, L.J, Fan, L. | 登録日 | 2015-05-08 | 公開日 | 2016-02-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water. Biochim.Biophys.Acta, 1864, 2016
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3E4P
| Crystal structure of malonate occupied DctB | 分子名称: | C4-dicarboxylate transport sensor protein dctB, MALONIC ACID, STRONTIUM ION | 著者 | Zhou, Y.F, Nan, J, Nan, B.Y, Liang, Y.H, Panjikar, S, Su, X.D. | 登録日 | 2008-08-12 | 公開日 | 2008-10-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain. J.Mol.Biol., 383, 2008
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5ZM3
| Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AndA with preandiloid B | 分子名称: | (6aS,8aR,12aS,12bR,13aR)-5,6a,9,9,12a,13a-hexamethyl-7,8,8a,9,11,12,12a,12b,13,13a-decahydro-3H-benzo[a]furo[3,4-j]xanthene-3,4,10(1H,6aH)-trione, 2-OXOGLUTARIC ACID, Dioxygenase andA, ... | 著者 | Nakashima, Y, Senda, T. | 登録日 | 2018-04-01 | 公開日 | 2018-07-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural and Computational Bases for Dramatic Skeletal Rearrangement in Anditomin Biosynthesis. J. Am. Chem. Soc., 140, 2018
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2VD7
| Crystal Structure of JMJD2A complexed with inhibitor Pyridine-2,4- dicarboxylic acid | 分子名称: | JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A, NICKEL (II) ION, PYRIDINE-2,4-DICARBOXYLIC ACID, ... | 著者 | Ng, S.S, von Delft, F, Pilka, E.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U. | 登録日 | 2007-10-01 | 公開日 | 2007-11-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases. J. Med. Chem., 51, 2008
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5C22
| Crystal structure of Zn-bound HlyD from E. coli | 分子名称: | Chromosomal hemolysin D, ZINC ION | 著者 | Ha, N.C, Kim, J.S. | 登録日 | 2015-06-15 | 公開日 | 2016-02-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Crystal Structure of a Soluble Fragment of the Membrane Fusion Protein HlyD in a Type I Secretion System of Gram-Negative Bacteria Structure, 24, 2016
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4I7Y
| Crystal Structure of Human Alpha Thrombin in Complex with a 27-mer Aptamer Bound to Exosite II | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, DNA (27-MER), ... | 著者 | Pica, A, Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. | 登録日 | 2012-12-01 | 公開日 | 2013-10-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer. Acta Crystallogr.,Sect.D, 69, 2013
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2FIK
| Structure of a microbial glycosphingolipid bound to mouse CD1d | 分子名称: | (2S,3R)-3-HYDROXY-2-(TETRADECANOYLAMINO)OCTADECYL ALPHA-D-GALACTOPYRANOSIDURONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, D, Zajonc, D.M. | 登録日 | 2005-12-29 | 公開日 | 2006-03-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3E67
| Murine inos dimer with inhibitor 4-MAP bound | 分子名称: | 4-METHYLPYRIDIN-2-AMINE, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ... | 著者 | Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stueh, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D. | 登録日 | 2008-08-14 | 公開日 | 2008-10-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
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