PDB: 47902 件ウェブページステータス検索Chemie searchBIRD

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6B7D	Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 3-(4-chlorophenyl)-6-methoxy-4,5-dimethylpyridazine 分子名称: 3-(4-chlorophenyl)-6-methoxy-4,5-dimethylpyridazine, DIMETHYL SULFOXIDE, POTASSIUM ION, ... 著者 Proudfoot, A.W, Bussiere, D, Lingel, A. 登録日 2017-10-03 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
3FB8	KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion 分子名称: RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... 著者 Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. 登録日 2008-11-18 公開日 2010-05-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion TO BE PUBLISHED
2VA6	X-ray crystal structure of beta secretase complexed with compound 24 分子名称: (6S)-2-amino-6-(3'-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one, BETA SECRETASE 1, IODIDE ION 著者 Edwards, P.D, Albert, J.S, Sylvester, M, Aharony, D, Andisik, D, Callaghan, O, Campbell, J.B, Carr, R.A, Chessari, G, Congreve, M, Frederickson, M, Folmer, R.H.A, Geschwindner, S, Koether, G, Kolmodin, K, Krumrine, J, Mauger, R.C, Murray, C.W, Olsson, L.L, Patel, S, Spear, N, Tian, G. 登録日 2007-08-30 公開日 2007-11-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine Beta-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency. J.Med.Chem., 50, 2007
3FBY	The crystal structure of the signature domain of cartilage oligomeric matrix protein. 分子名称: CALCIUM ION, Cartilage oligomeric matrix protein, SULFATE ION, ... 著者 Tan, K, Lawler, J. 登録日 2008-11-20 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 The crystal structure of the signature domain of cartilage oligomeric matrix protein: implications for collagen, glycosaminoglycan and integrin binding. Faseb J., 23, 2009
2FG4	Structure of Human Ferritin L Chain 分子名称: CADMIUM ION, Ferritin light chain 著者 Wang, Z, Li, C, Ellenburg, M, Ruble, J, Ho, J.X, Carter, D.C. 登録日 2005-12-21 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of human ferritin L chain. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
4JCW	Crystal structure of Clavibacter michiganensis expansin in complex with cellopentaose 分子名称: beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, cellulose binding protein 著者 Yennawar, N.H, Yennawar, H.P, Georgelis, N, Cosgrove, D.J. 登録日 2013-02-22 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of wild type and D78N mutant Clavibacter michiganensis expansin, in apo form and in complex with oligosaccharides To be Published
2V2R	Mutant (E53,56,57,60Q and R59M) recombinant horse spleen apoferritin cocrystallized with haemin in basic conditions 分子名称: CADMIUM ION, FERRITIN LIGHT CHAIN, GLYCEROL, ... 著者 De Val, N, Declercq, J.P. 登録日 2007-06-06 公開日 2008-06-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Analysis of Haemin Demetallation by L-Chain Apoferritins J.Inorg.Biochem., 112, 2012
2VEI	Structure-based enzyme engineering efforts with an inactive monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties 分子名称: GLYCOSOMAL TRIOSEPHOSPHATE ISOMERASE, SULFATE ION 著者 Alahuhta, M, Salin, M, Casteleijn, M.G, Kemmer, C, El-Sayed, I, Augustyns, K, Neubauer, P, Wierenga, R.K. 登録日 2007-10-24 公開日 2008-02-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structure-Based Protein Engineering Efforts with a Monomeric Tim Variant: The Importance of a Single Point Mutation for Generating an Active Site with Suitable Binding Properties. Protein Eng.Des.Sel., 21, 2008
2VJX	Structural and biochemical evidence for a boat-like transition state in beta-mannosidases 分子名称: (3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE, 1,2-ETHANEDIOL, BETA-MANNOSIDASE, ... 著者 Tailford, L.E, Offen, W.A, Smith, N.L, Dumon, C, Moreland, C, Gratien, J, Heck, M.P, Stick, R.V, Bleriot, Y, Vasella, A, Gilbert, H.J, Davies, G.J. 登録日 2007-12-14 公開日 2008-04-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases. Nat.Chem.Biol., 4, 2008
2FJG	Structure of the G6 Fab, a phage derived Fab fragment, in complex with VEGF 分子名称: Fab heavy chain, Fab light chain, SULFATE ION, ... 著者 Wiesmann, C. 登録日 2006-01-02 公開日 2006-02-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab. J.Biol.Chem., 281, 2006
4JEP	Crystal structure of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) 分子名称: Nucleoside-triphosphatase 2 著者 Krug, U, Totzauer, R, Strater, N. 登録日 2013-02-27 公開日 2013-04-10 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The crystal structure of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 represents a conformational intermediate in the reductive activation mechanism of the tetrameric enzyme. Proteins, 81, 2013
4JFE	Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
3FE7	Crystal Structure of HdmX bound to the p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-Trp-Glu-Ac3c-Leu-NH2 at 1.35A 分子名称: Mdm4 protein, p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-Trp-Glu-Ac3c-Leu-NH2 著者 Kallen, J. 登録日 2008-11-28 公開日 2009-01-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes J.Biol.Chem., 284, 2009
4JFW	Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(propylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol 分子名称: (3alpha)-[3-({2-[(2S,3S,4R,5S)-3,4-dihydroxy-5-methylpyrrolidin-2-yl]ethyl}amino)propyl]ferrocene, IMIDAZOLE, SULFATE ION, ... 著者 Wright, D.W, Davies, G.J. 登録日 2013-02-28 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 alpha-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studies. Chemistry, 19, 2013
2FM6	Zinc-beta-lactamase L1 from stenotrophomonas maltophilia (native form) 分子名称: GLYCEROL, Metallo-beta-lactamase L1, SULFATE ION, ... 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-01-07 公開日 2007-01-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
2FHA	HUMAN H CHAIN FERRITIN 分子名称: CALCIUM ION, FERRITIN 著者 Hempstead, P.D, Artymiuk, P.J, Harrison, P.M. 登録日 1997-03-03 公開日 1997-09-04 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Comparison of the three-dimensional structures of recombinant human H and horse L ferritins at high resolution. J.Mol.Biol., 268, 1997
4Z6W	Structure of H200N variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-nitrocatechol at 1.57 Ang resolution 分子名称: 4-NITROCATECHOL, CALCIUM ION, CHLORIDE ION, ... 著者 Kovaleva, E.G, Lipscomb, J.D. 登録日 2015-04-06 公開日 2015-08-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry, 54, 2015
5D0U	Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Tauchert, M.J, Ficner, R. 登録日 2015-08-03 公開日 2016-02-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.919 Å) 主引用文献 Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 72, 2016
2VCV	Glutathione transferase A3-3 in complex with glutathione and delta-4- androstene-3-17-dione 分子名称: 4-ANDROSTENE-3-17-DIONE, GLUTATHIONE, GLUTATHIONE S-TRANSFERASE A3 著者 Tars, K, Olin, B, Mannervik, B. 登録日 2007-09-27 公開日 2008-10-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases. J.Mol.Biol., 397, 2010
1KQZ	Hevamine Mutant D125A/E127A/Y183F in Complex with Tetra-NAG 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hevamine A 著者 Rozeboom, H.J, Dijkstra, B.W. 登録日 2002-01-08 公開日 2002-01-23 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Expression and Characterization of Active Site Mutants of Hevamine, a Chitinase from the Rubber Tree Hevea brasiliensis. Eur.J.Biochem., 269, 2002
5DI1	MAP4K4 in complex with an inhibitor 分子名称: 4-{6-amino-5-[4-(methylsulfonyl)phenyl]pyridin-3-yl}phenol, Mitogen-activated protein kinase kinase kinase kinase 4 著者 Liu, S. 登録日 2015-08-31 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment. Acs Med.Chem.Lett., 6, 2015
3FJM	crystal structure of phosphate bound PEB3 分子名称: Major antigenic peptide PEB3, PHOSPHATE ION 著者 Min, T, Matte, A, Cygler, M. 登録日 2008-12-14 公開日 2009-03-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Specificity of Campylobacter jejuni adhesin PEB3 for phosphates and structural differences among its ligand complexes. Biochemistry, 48, 2009
4JMQ	Crystal structure of pb9: The Dit of bacteriophage T5. 分子名称: Bacteriophage T5 distal tail protein 著者 Flayhan, A, Vellieux, F.M.D, Girard, E, Maury, O, Boulanger, P, Breyton, C. 登録日 2013-03-14 公開日 2013-11-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.895 Å) 主引用文献 Crystal Structure of pb9, the Distal Tail Protein of Bacteriophage T5: a Conserved Structural Motif among All Siphophages. J.Virol., 88, 2014
2EZA	AMINO TERMINAL DOMAIN OF ENZYME I FROM ESCHERICHIA COLI, NMR, RESTRAINED REGULARIZED MEAN STRUCTURE 分子名称: PHOSPHOTRANSFERASE SYSTEM, ENZYME I 著者 Clore, G.M, Tjandra, N, Garrett, D.S, Gronenborn, A.M. 登録日 1997-05-07 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy. Nat.Struct.Biol., 4, 1997
4ZCV	Structure of calcium-bound regulatory domain of the human ATP-Mg/Pi carrier in the P212121 form 分子名称: CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, GLYCEROL, ... 著者 Harborne, S.P.D, Ruprecht, J.J, Kunji, E.R.S. 登録日 2015-04-16 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier. Biochim.Biophys.Acta, 1847, 2015

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